Curriculum Vitaes
Profile Information
- Affiliation
- Radiology Division Theragnostics Centre, Fujita Health University Hospital
- ORCID ID
https://orcid.org/0009-0008-0980-1767- researchmap Member ID
- B000230480
Specializing in in-house production of radiopharmaceuticals, quality control, and system-level workflow design, he focuses on optimizing the entire operational framework of radiopharmaceutical practice, including PET tracer synthesis, QC, supply management, and education systems.
In recent years, his work has emphasized the development of sustainable operational systems in clinical settings by integrating troubleshooting experiences and practical knowledge into structured workflows and educational resources.
After graduating from the Faculty of Engineering at Tottori University, he pursued graduate studies in material and biological informatics at the Graduate School of Human Informatics, Nagoya University. He subsequently engaged in research and technical development in both industry and research institutions, including the National Institute of Advanced Industrial Science and Technology (AIST), the National Center for Geriatrics and Gerontology, and Nagoya University, and obtained a doctoral degree in protein chemistry. He is currently involved in the production and operational management of radiopharmaceuticals at Fujita Health University Hospital.
Major Papers
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RADIOISOTOPES, 75(3) 1-8, Nov 15, 2026 Peer-reviewedLead authorLast authorCorresponding author
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Nuclear Medicine Communications, 47(11), Nov, 2026 Peer-reviewedLead authorCorresponding authorAccepted for publication in Nuclear Medicine Communications (June 2026). Co-first authors: Masanori Watanabe and Hiroshi Yamaguchi.
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Radiochimica Acta, Oct 26, 2026 Peer-reviewedLead authorCorresponding author2026年8月25日 受理（Accepted）
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Nuclear Medicine Communications, Oct 13, 2026 Peer-reviewedLead authorLast authorCorresponding authorPurpose The study aimed to develop and evaluate a practical model for determining cyclotron irradiation time based on planned fluorodeoxyglucose (FDG) supply in a hospital-based production setting. Methods Irradiation time was calculated using a composite coefficient of 2.8 min per GBq of planned clinical demand. The coefficient integrated a facility-specific conversion between required end-of-bombardment activity and irradiation time, a conservative synthesis yield of 55%, quality control activity consumption of 11.1%, radioactive decay during an approximately 30-min processing interval, and an operational safety factor of 1.2. Results During a fixed 24-month evaluation period, the model was applied on 516 consecutive scheduled FDG production days. Sufficient FDG activity was supplied for all scheduled examinations on all 516 days (100%), with no activity shortage attributable to underestimation of the required irradiation time. Conclusion A demand-based irradiation model incorporating conservative yield assumptions, quality control consumption, and handling margins enables reliable FDG supply while maintaining an appropriate activity margin. This approach provides a practical framework for hospital-based radiopharmaceutical production.
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Nuclear Medicine Communications, 47(10) 1218-1219, Oct, 2026 Lead authorLast authorCorresponding author
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74(10), Oct, 2026 Peer-reviewedLast authorCorresponding author
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Nuclear Medicine Communications, Jul 28, 2026 Peer-reviewedLead authorLast authorCorresponding authorThis technical note reports threshold behavior of droplet release in automated [¹⁸F]FDG quality control. During routine operation of an automated QC system, small-volume dispensing showed unstable droplet release, resulting in misplacement on test media. Droplet behavior was sensitive to programmed dispensing volume: 0.011 mL frequently resulted in adhesion to the needle tip, 0.012 mL showed borderline behavior, and 0.013 mL restored stable release. The findings highlight the importance of periodic verification and adaptive adjustment of dispensing parameters in automated radiopharmaceutical quality control.
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Journal of Nuclear Medicine Technology, Jul 21, 2026 Peer-reviewedLead authorLast authorCorresponding authorRoutine maintenance of a radio-HPLC detector system resulted in an unintended shift of the detector energy window from 511 keV to approximately 400 keV, causing substantial signal attenuation during radiopharmaceutical quality control. This report describes the incident, root cause analysis, and the role of technologists and site engineers in identifying and resolving the problem.
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Journal of Nuclear Medicine Technology, Jun 23, 2026 Peer-reviewedLead authorCorresponding author
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Applied Radiation and Isotopes, 231 112496-112496, May, 2026 Peer-reviewedLead authorLast authorCorresponding author
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Applied Radiation and Isotopes, 112563-112563, Mar 21, 2026 Peer-reviewedLead authorLast authorCorresponding author
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Journal of Nuclear Medicine Technology, 54(1), Feb 10, 2026 Peer-reviewedLead authorLast authorCorresponding author
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Journal of Clinical Engineering, In press, 2026 Peer-reviewedLead authorLast authorCorresponding authorAccepted for publication in the October–December 2026 issue of the Journal of Clinical Engineering.
Misc.
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Zenodo, Oct 11, 2026 Lead authorCorresponding authorVariation in professional training can reflect appropriate adaptation to learners and local conditions. It can also obscure inconsistent expectations for assessment or unsupervised practice. This perspective proposes a distinction between adaptive teaching variation and uncontrolled variation in essential competency requirements. A training variance log is suggested to help programs identify the decision affected, its potential consequence, and the need for clarification. The proposed pathway from unclear training expectations to inconsistent professional decisions is a hypothesis, not a demonstrated patient safety effect. No retrospective dataset or improvement following standardization is reported. The paper argues for selective agreement on essential criteria while preserving reasonable instructional flexibility. Evaluation should address assessment consistency, learner understanding, and the burden of maintaining shared criteria. This is a conceptual perspective and has not been peer reviewed.
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Zenodo, Oct 4, 2026 Lead authorCorresponding authorInternational clinical training in radiopharmaceutical production requires supervision within time-sensitive workflows involving radiation safety, quality control, and multidisciplinary coordination. This practice-informed perspective examines how a mismatch between institutional training commitments and frontline supervisory capacity may create hidden operational burdens.It discusses trainee preparedness, staged participation, protected supervisory time, clear responsibility allocation, and escalation pathways as elements of sustainable program design. Drawing on experience from a single hospital-based environment, it offers a conceptual framework for supporting both trainees and supervisors while maintaining clinical operations.This preprint has not been peer reviewed. It reports no original participant dataset, quantified supervisory workload, or measured intervention outcomes. The proposed relationships and governance responses have not been empirically validated.
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Zenodo, Oct 4, 2026 Lead authorCorresponding authorProfessional expertise does not by itself establish the ability to teach, assess, and support learners. This conceptual perspective examines educator competency as an organizational responsibility in healthcare professional training. It proposes a governance cycle linking appointment, preparation, instructional expectations, assessment review, and continuing support. Four practical questions guide the framework: who is authorized to teach, what preparation is provided, how learner assessment is reviewed, and how concerns lead to support or corrective action. The proposed cycle is intended as a discussion framework, not a validated accreditation instrument. No original participant dataset, intervention evaluation, or patient outcome analysis is reported. This preprint has not been certified by peer review.
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Operational Protocol for Sustainable FDG Production in Hospital-Based Radiopharmaceutical FacilitiesUnpublished Technical Report (Institutional Document), Apr, 2026 Lead authorLast authorCorresponding authorThis report presents a structured operational protocol for sustainable 18F-FDG production in hospital-based radiopharmaceutical facilities. The protocol integrates routine workflow, troubleshooting processes, and education-driven system design to ensure stable and safe production. Rather than treating operational issues as isolated events, this framework systematically converts troubleshooting experiences into standardized workflows and training resources. This approach enables continuous system improvement and transforms operational variability into structured system resilience in radiopharmaceutical practice.
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Unpublished Technical Report (Institutional Document), Apr, 2026 Lead authorLast authorCorresponding authorThis report presents a structured operational framework for medical supply management in hospital-based radiopharmaceutical production environments without centralized SPD systems. The framework integrates demand forecasting, inventory control (including FEFO principles), supplier dependency assessment, and risk mitigation strategies. It emphasizes the dynamic interaction between procurement constraints, hospital policies, and production requirements. This approach highlights how supply constraints can translate into hidden operational burdens and provides practical strategies to enhance system resilience and continuity in radiopharmaceutical practice.
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Post-Maintenance Verification Protocol for Radio-HPLC Systems in Radiopharmaceutical Quality ControlUnpublished Technical Report (Institutional Document), Apr, 2026 Lead authorLast authorCorresponding authorThis report presents a practice-based verification protocol designed to address the risk of detector configuration drift following maintenance in radio-HPLC systems used for radiopharmaceutical quality control. The protocol aims to strengthen quality assurance in both routine operations and validation processes.
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第101回中部核医学研究会 口演発表, Feb 14, 2026 Peer-reviewedLead authorLast authorCorresponding authorFDGおよびPSMA放射性医薬品製造を支える院内サイクロトロン運用について報告した。製造体制の構築、品質管理、運用上の課題および今後の展望について、中部核医学研究会において発表した。
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BioJapan 2025 口演発表, Oct 9, 2025 Lead authorLast authorCorresponding author次世代セラノスティクスを支える68Ga製造プラットフォームについて報告した。病院内サイクロトロンを用いた68Ga製造技術、臨床実装に向けた運用体制、および地域供給を見据えた将来展望について紹介した。