Tamio Yamaguchi

(山口太美雄)

Profile Information

Affiliation: Visiting Professor, Fujita Health University

Degree: Ph.D.(Fujita Health University)

Researcher number: 70536292
J-GLOBAL ID: 201901012659725723
researchmap Member ID: B000362979

Research Interests

Polycystic Kidney Disease (PKD), Diabetic Kidney Disease (DKD) in vivo and in vitro model/platform

Research Areas

Life sciences / Experimental pathology / Utilizing extrapolation models of human diseases: Nephrology (Polycystic Kidney Disease, Diabetic Kidney Disease), Molecular and cellular biology, Pharmacology, Organoid

Research History

Committee Memberships

2022 - Present

Board Member, Polycystic Kidney Disease Association of Japan
2020 - Present

Member, Certified Functional Food Consultant Recertification Examination Committee, Japanese Association of Food Science and Risk Analysis
2019 - Present

Committee Member, Chubu Branch, Japanese Association of Food Science and Risk Analysis
2003 - Present

Academic Advisor, PKD Foundation Chapter of Japan
2017 - 2026

Organizer, Tokai Renal Function Assessment Study Group

Awards

Jul, 2021

Outstanding Paper Award, The Research Society for Science of Dietary Habits

Chizuko Hotta, Tamio Yamaguchi
Jun, 2011

Best Presentation Award, The 54th Annual Meeting of the Japanese Society of Nephrology

Atsushi Hoshihara, Hiroki Kurahashi, Miwa Morita, Masanori Kugita, Yoshiyuki Hiki, Harold Aukema, Tamio Yamaguchi, James Calve, Darren Wallace, Shizuko Nagao (Fujita Health University, JAPAN, University of Manitoba, CANADA, University of Kansas Medical Center, U.S,A,)
Feb, 2007

PKD Investigator Award (for Outstanding Contribution of Research and Service), Kansas Interdisciplinary PKD Research Center, Kansas City, KS, U.S.A.

Tamio Yamaguchi, Ph.D., Research Assistant Professor, University of Kansas Medical Center, U.S.A.
Jul, 1999

Biomedical Research Scholar Award, University of Kansas Medical Center Training Program in Biomedical Research, Kansas City, KS, U.S.A.

Tamio Yamaguchi, Ph.D., Post-Doctoral Fellow, University of Kansas Medical Center, U.S.A.
Jul, 1998

Kansas Health Foundation Scholar Award, Kansas Health Foundation Cancer Research and Training Program, State of Kansas, U.S.A.

Tamio Yamaguchi, Ph.D., Post-Doctoral Fellow, University of Kansas Medical Center, U.S.A.

Papers

Intracellular signaling cascades and cell proliferation in polycystic kidney disease

Tamio Yamaguchi, Aya Yoshimura, Masanori Kugita, Shizuko Nagao

Kidney and Dialysis, 100(3) 346-350, Mar, 2026 InvitedLead authorCorresponding author
Current advance in animal models underpinning PKD research

Shizuko Nagao, Masanori Kugita, Aya Yoshimura, Tamio Yamaguchi

Kidney and Dialysis, 100(3) 334-338, Mar, 2026 InvitedLast author
セリノール核酸から合成した抗miR-21オリゴヌクレオチドのヒト,マウス嚢胞性腎疾患モデルに対する改善効果

野田悠平, 加藤規利, 山口太美雄, 長尾静子, 神谷由紀子, 浅沼浩之, 丸山彰一

日本腎臓学会誌, 67(4) 511-511, Jun, 2025
ETA受容体選択的拮抗薬を投与した食塩負荷SDT fattyラットの病理および遺伝子発現解析

福井渓実, 白水貴大, 釘田雅則, 熊本海生航, 山口太美雄, 高橋和男, 吉村文, 長尾静子

日本腎臓学会誌, 67(4) 543-543, Jun, 2025
食塩負荷SDT fattyにおけるMR拮抗薬とETAR拮抗薬の併用による降圧および腎保護作用

白水貴大, 吉村文, 福井渓実, 釘田雅則, 熊本海生航, 八代百合子, 白倉美雨, 大畑敬一, 秋江靖樹, 山口太美雄, 高橋和男, 長尾静子

日本腎臓学会誌, 67(4) 543-543, Jun, 2025

Misc.

109

Salt-sensitive genetic background strongly supresses medullary cyst formation in ARPKD rat model

Aya Yoshimura, Takahiro Shirozu, Masanori Kugita, Kanako Kumamoto, Akiko Takizawa, Melinda R. Dwinell, Masumi Hirabayashi, Kazuo Takahashi, Tamio Yamaguchi, Shizuko Nagao

World Congress of Nephrology 2026 (WCN '26), Yokohama, Japan, P520, Mar 30, 2026 Peer-reviewed
Improvement of hypertension, albuminuria, dyslipidemia, and renal impairment in salt-loaded SDT fatty rats by a mineralcorticoid receptor antagonist.

Takahiro Shirozu, Aya Yoshimura, Masanori Kugita, Kanako Kumamoto, Yuriko Yatsushiro, Miu Shirakura, Keiichi Ohata, Yasuki Akie, Tamio Yamaguchi, Kazuo Takahashi, Shizuko Nagao

World Congress of Nephrology 2026 (WCN '26), Yokohama, Japan, P323, Mar 28, 2026 Peer-reviewed
Antihypertensive and renoprotective effects of mineralocorticoid receptor antagonist on salt-loaded SDT fatty rat with diabetic nephropathy

Takahiro Shirozu, Aya Yoshimura, Masanori Kugita, Kanako Kumamoto, Yuriko Yatsushiro, Miu Shirakura, Keiichi Ohata, Yasuki Akie, Tamio Yamaguchi, Kazuo Takahashi, Shizuko Nagao

2025 Asian Pacific Congress of Nephrology (APCN), Taipei, Taiwan, Dec 5, 2025
Additive Antihypertensive and Renoprotective Effects of a Mineralocorticoid Receptor Antagonist Combined with an Endothelin Receptor Type A-Selective Antagonist in Salt-Loaded Spontaneously Diabetic Torii Rats

Takahiro Shirozu, Aya Yoshimura, Masanori Kugita, Kanako Kumamoto, Yuriko Yatsushiro, Miu Shirakura, Keiichi Ohata, Yasuki Akie, Tamio Yamaguchi, Kazuo Takahashi, Shizuko Nagao

American Society of Nephrology (ASN) KIDNEY WEEK 2025, Houston, U.S.A., Nov 8, 2025
ETA受容体選択的拮抗薬を投与した食塩負荷SDT fattyラットの病理および遺伝子発現解析

福井渓実, 白水貴大, 釘田雅則, 熊本海生航, 山口太美雄, 高橋和男, 吉村文, 長尾静子

日本腎臓学会誌(Web), 67(4), 2025
食塩負荷SDT fattyにおけるMR拮抗薬とETAR拮抗薬の併用による降圧および腎保護作用

白水貴大, 吉村文, 福井渓実, 釘田雅則, 熊本海生航, 八代百合子, 白倉美雨, 大畑敬一, 秋江靖樹, 山口太美雄, 高橋和男, 長尾静子

日本腎臓学会誌(Web), 67(4), 2025
セリノール核酸から合成した抗miR-21オリゴヌクレオチドのヒト,マウス嚢胞性腎疾患モデルに対する改善効果

野田悠平, 加藤規利, 山口太美雄, 長尾静子, 神谷由紀子, 浅沼浩之, 丸山彰一

日本腎臓学会誌(Web), 67(4), 2025
食塩負荷を伴う肥満2型糖尿病モデルラットの降圧薬による腎保護作用:リキッドバイオマーカーによる検証

吉村文, 白水貴大, 釘田雅則, 熊本海生航, 八代百合子, 白倉美雨, 大畑敬一, 秋江靖樹, 山口太美雄, 長尾静子

日本実験動物学会総会講演要旨集(Web), 72nd, 2025
Unveiling Renal Disease Progression in Autosomal Recessive Polycystic Kidney Disease with Hypertension: Insights from SS-PCK Rat Model

Aya Yoshimura, Takahiro Shirozu, Masanori Kugita, Kanako Kumamoto, Akiko Takizawa, Melinda R. Dwinell, Masumi Hirabayashi, Kazuo Takahashi, Harold M. Aukema, Tamio Yamaguchi, Shizuko Nagao

American Society of Nephrology, KIDNEY WEEK 2024, San Diego, U.S.A., Oct 26, 2024 Peer-reviewed
Ameliorative Effect of Anti-microRNA-21 Oligonucleotide Synthesized from Serinol nucleic acid on Animal and Human Models of Cystic Kidney Disease.

Yuhei Noda, Noritoshi Kato, Yuka Sato, Kayaho Maeda, Tamio Yamaguchi, Shizuko Nagao, Tomoki Kosugi, Yukiko Kamiya, Hiroyuki Asanuma, Shoichi Maruyama

American Society of Nephrology, KIDNEY WEEK 2024, San Diego, U.S.A., Oct 24, 2024 Peer-reviewed
Antihypertensive effects of endothelin receptor antagonists on a diabetic nephropathy-induced SDT fatty rat with hypertension

Takahiro Shirozu, Aya Yoshimura, Masanori Kugita, Yuriko Yatsushiro, Yoshiyuki Suzuki, Keiichi Ohata, Yasuki Akie, Tamio Yamaguchi, Kazuo Takahashi, Shizuko Nagao

2024 Asian Pacific Congress of Nephrology (APCN), Seoul, Korea, Jun 13, 2024 Peer-reviewed
Characteristics of a novel rat model of autosomal recessive polycystic kidney disease with salt-sensitive hypertension

Aya Yoshimura, Eriko Matsuyama, Masanori Kugita, Takahiro Shirozu, Akiko Takizawa, Melinda R Dwinell, Masumi Hirabayashi, Kazuo Takahashi, Tamio Yamaguchi, Shizuko Nagao

2024 Asian Pacific Congress of Nephrology (APCN), Seoul, Korea, Jun 13, 2024 Peer-reviewed
高血圧誘発SDT fattyラットにおけるエンドセリンA型受容体選択的拮抗薬による糖尿病性腎症の進行抑制効果

白水貴大, 吉村文, 坂田美和, 熊本海生航, 釘田雅則, 八代百合子, 鈴木慶幸, 大畑敬一, 秋江靖樹, 山口太美雄, 高橋和男, 長尾静子

日本腎臓学会誌, 66(4) 657-657, Jun, 2024 Peer-reviewed
Sox2/CD63-GFP transgenic rat: A novel model for nephrogenic diabetes insipidus

Aya Yoshimura, Takahiro Shirozu, Masanori Kugita, Kanako Kumamoto, Tamio Yamaguchi, Shizuko Nagao

American Society of Nephrology, KIDNEY WEEK 2023, Philadelphia, U.S.A., Nov, 2023 Peer-reviewed
Comparative Transcriptome Analysis of Spontaneously Diabetic Torii Fatty Rat Undergoing Salt Loading Alone or with Unilateral Nephrectomy

American Society of Nephrology, KIDNEY WEEK 2023, Philadelphia, U.S.A. 2023, Nov, 2023 Peer-reviewed
慢性疼痛で学ぶチーム医療（実践）

上條史絵, 丸山淳子, 山口太美雄

医療人の底力実践三重大学出版会, 第4版 199, Mar, 2023
遺伝子技術関連食品

山口太美雄

食の機能と健康の科学（分担執筆）日本食品安全協会編, P30-33, Mar, 2022
Altered cellular signaling pathways identified by proteomics and phospho-proteomics in a rat model of diabetic kidney disease.

Aya Yoshimura, Masanori Kugita, Hisateru Yamaguch, Kazuki Nakajima, Kanako Kumamoto, Tamio Yamaguchi, Kazuo Takahashi, Yukio Yuzawa, Shizuko Nagao

Nov, 2021 Peer-reviewed
Comparison of the effect of calorie matched high saturated-fat and high unsaturated-fat diets on lysosomal renal injury in non-obese, streptozotocin-injected CD-1 mice

Tamio Yamaguchi, Aya Yoshimura, Masanori Kugita, Kanako Kumamoto, Kazuya Shiogama, Shizuko Nagao

American Society of Nephrology, KIDNEY WEEK Reimagined 2020 (remote presentation), Oct, 2020 Peer-reviewedLead author
同一摂取カロリーでラードとスクロースの比率を高めた場合の非肥満糖尿病マウスの血糖動態と腎傷害発現

吉村文, 山口太美雄, 釘田雅則, 熊本海生航, 塩竈和也, 荻津直通, 三浦俊宏, 米田操, 長村洋一, 長尾静子

日本腎臓学会誌, 62(4) 283-283, Jul, 2020
Development and implantation of novel morphometric 3-D capsule device to constrain structural change of polycystic kidney: a feasibility study in a rat model

Kyongtae T. Bae, Kanako Kumamoto, Aya Yoshimura, Masanori Kugita, Shigeo Horie, TamioYamaguchi, Junu Bae, Shizuko Nagao

Nov, 2019 Peer-reviewed
嚢胞性腎疾患モデル動物の腎オキシリピン組成にみる治療法のヒント

山口太美雄, Harold M. Aukema, 長尾静子

第27回嚢胞性腎疾患研究会（東京虎ノ門スカイガーデン）, Oct 5, 2019 Lead author
糖尿病誘発マウス血糖値に対する低炭水化物高脂肪（LCHF）食と低脂肪高炭水化物（LFHC）食の影響

山口太美雄, 釘田雅則, 吉村文, 熊本海生航, 三浦俊宏, 米田操, 荻津直道, 長村洋一, 長尾静子

第89回東海実験動物研究会（名古屋市立大学医学部研究棟）, Jul 14, 2018 Lead author
Low carbohydrate high fat diet exacerbates streptozotocin-induced diabetes compared to calorie matched low fat high carbohydrate diet in ICR mice.

Tamio Yamaguchi, Shizuko Nagao, Masanori Kugita, Kanako Kumamoto, Aya Yoshimura, Naomichi Ogitsu, Toshihiro Miura, Misao Yoneda, Yoichi Nagamura

American Society for Nutrition "NUTRITION 2018" Boston, U.S.A., Jun, 2018 Peer-reviewedLead author
多発性嚢胞腎症モデルPCKラットの腎臓におけるメタボローム解析―グルコース代謝経路について―

釘田雅則, 熊本海生航, 吉村文, 山口太美雄, 長尾静子

日本実験動物学会総会講演要旨集, 65th 215, Apr 27, 2018
Renal and serum oxylipin alterations in the jck mouse, an orthologous model of human nephronophthisis.

Tamio Yamaguchi, Md Monirujjaman, Jessay G Devassy, Melissa Gabbs, Nikhil Sidhu, Masanori Kugita, Arun Surendran, Shizuko Nagao, Amir Ravandi, Harold M Aukema

International Society of Nephrology (ISN) Frontiers Meetings, Tokyo, Japan, Feb, 2018 Peer-reviewedLead author
多発性嚢胞腎症のモデル動物であるPCKラットにおける飲水量増加による病態進行抑制に対する塩分摂取の影響

釘田雅則, 山口太美雄, 長村洋一, Aukema Harold, 長尾静子

生命科学系学会合同年次大会, 2017年度 [2P-1129], Dec, 2017
Altered liver bioactive lipid (oxylipin) profiles in PCK rats with polycystic kidney and liver disease.

Tamio Yamaguchi T, Jessay G Devassy, Aruni Jha, Andrew J Halayko, Masanori Kugita, Shizuko Nagao, Amir Ravandi, Harold M Aukema

American Society of Nephrology KIDNEY WEEK 2017, New Orleans, U.S.A., Nov, 2017 Peer-reviewedLead author
Increased salt intakes have an insignificant effect on amelioration in renal cystic disease progression in PCK rats with high water intakes

KUGITA Masanori, YAMAGUCHI Tamio, NAGAMURA Yoichi, NAGAO Shizuko

日本実験動物学会総会講演要旨集, 64th 192, Apr 28, 2017
ネフロン癆モデルマウス腎組織におけるCOXにより産生されるオキシリピンの増加

山口太美雄, Aukema Harold, Devassy Jessay, Sidhu Nikhil, Gabbs Melissa, Ravandi Amir, 釘田雅則, 長尾静子

日本腎臓学会誌, 59(3) 327-327, Apr, 2017 Peer-reviewedLead author
Bioactive lipid alterations in the jck and pcy mouse models of nephronophthisis

Tamio Yamaguchi, Nikhil Sidhu, Jessay G Devassy, Melissa Gabbs, Amir Ravandi, Masanori Kugita, Shizuko Nagao, Harold M Aukema

Annual Meeting of the American Society of Nephrology KIDNEY WEEK 2016, Chicago, U.S.A., Nov, 2016 Peer-reviewedLead author
Early Intervention with Dietary Fish Oil, Flax Oil and Soy Protein in Three Orthologous Rodent Models of Human Hereditary Polycystic Kidney Disease

Jessay Gopuran Devassy, Tamio Yamaguchi, Md Monirujjaman, Melissa Gabbs, Madelaine Morrish, Harold M. Aukema

FASEB JOURNAL, 30, Apr, 2016
Cyclooxygenase (COX) Derived Oxylipins are Elevated in Models of Polycystic Kidney Disease, Indicating Potential for COX Inhibition to Treat Disease

Md Monirujjaman, J. G. Devassy, T. Yamaguchi, Melissa Gabbs, Tanja Winter, A. Ravandi, H. M. Aukema

FASEB JOURNAL, 30, Apr, 2016
Dietary alpha-Linolenic Acid (ALA) Rich Flax Oil Elevates Renal and Hepatic Docsosahexaenoic Acid (DHA) Derived Bioactive Lipids

Jessay Gopuran Devassy, Tamio Yamaguchi, Naser Ibrahim, Melissa Gabbs, Tanja Winter, Amir Ravandi, Harold M. Aukema

FASEB JOURNAL, 30, Apr, 2016
その他の薬剤基礎研究

長尾静子, 山口太美雄

多発性嚢胞腎進化する治療最前線（東原英二編）分担執筆医薬ジャーナル社, P192-197, Aug, 2015 Last author
トルバプタン基礎研究

長尾静子, 山口太美雄

多発性嚢胞腎進化する治療最前線（東原英二編）分担執筆医薬ジャーナル社, P144-150, Aug, 2015 Last author
cAMPによる嚢胞形成

山口太美雄, 長尾静子

多発性嚢胞腎進化する治療最前線（東原英二編）分担執筆医薬ジャーナル社, P45-53, Aug, 2015 Lead author
常染色体劣性多発性嚢胞腎症モデル動物であるPCKラットにおけるGi作動薬の併用治療効果

吉原大輔, 釘田雅則, 西井一宏, 鈴木敦詞, 湯澤由紀夫, 東原英二, 堀江重郎, 山口太美雄, 長尾静子

日本腎臓学会誌, 57(3) 535-535, Apr, 2015
嚢胞性腎疾患モデル動物

長尾静子, 釘田雅則, 吉原大輔, 佐々木麻衣, 山口太美雄

腎臓内科・泌尿器科, 1(2) 180-193, Feb, 2015
多発性嚢胞腎症のモデル動物であるPCKラットにおけるGi作動薬の病態進行抑制効果

釘田雅則, 吉原大輔, 西井一宏, 鈴木敦詞, 湯澤由紀夫, 山口太美雄, 堀江重郎, 東原英二, 長尾静子

日本実験動物学会総会講演要旨集, 62nd, 2015
【病態解析のための動物モデル-何がわかったか】ヒト多発性嚢胞腎症の動物モデル発生病態の解析

長尾静子, 釘田雅則, 吉原大輔, 佐々木麻衣, 山口太美雄

小児外科, 46(6) 644-649, Jun, 2014
テルミサルタンによるヒト常染色体劣性多発性嚢胞腎症オーソログ遺伝子変異モデルにおける病態発現抑制効果

長尾静子, 吉原大輔, 釘田雅則, 佐々木麻衣, 堀江重郎, 中西浩一, 阿部高明, 山口太美雄

日本小児腎臓病学会雑誌, 26(1Suppl.) 213-213, May, 2013
A targeted lipidomic analysis of renal oxylipins in kidney disease reveals differences in the effects of dietary flax compared to fish oil

Jessay Gopuran Devassy, Tamio Yamaguchi, Naser Ibrahim, Amir Ravandi, Harold M. Aukema

FASEB JOURNAL, 27, Apr, 2013
ヒト多発性嚢胞腎症モデル動物の有用性と必要性

長尾静子, 釘田雅則, 吉原大輔, 山口太美雄

日本実験動物学会総会講演要旨集, 60th, 2013
Basic nephrology 分子生物学多発性嚢胞腎発症のメカニズム

長尾静子, 釘田雅則, 吉原大輔, 山口太美雄

Annual Review腎臓, 2013 101-108, Jan, 2013
ラット多発性嚢胞腎におけるPPARγアゴニスト投与の治療効果に関する網羅的遺伝子発現プロファイリング

吉原大輔, 釘田雅則, 倉橋浩樹, 森田美和, 比企能之, 山口太美雄, 豊原敬文, 阿部高明, 長尾枝澄香

日本腎臓学会誌, 54(3) 281-281, Apr, 2012
多発性嚢胞腎症モデル動物の腎臓におけるretinoid X receptor(RXR)の発現と局在

釘田雅則, 吉原大輔, 山口太美雄, 長尾静子

日本実験動物学会総会講演要旨集, 59th, 2012
Animal models for human polycystic kidney disease.

Shizuko Nagao, Masanori Kugita, Daisuke Yoshihara, Tamio Yamaguchi

Experimental animals, 61(5) 477-88, 2012 Last author
ヒト多発性嚢胞腎症のラットモデルにおけるPPAR-γアゴニストの治療効果

吉原大輔, 倉橋浩樹, 森田美和, 釘田雅則, 比企能之, Harold Aukema, 山口太美雄, Calvet James, Darren Wallace, 長尾枝澄香

日本腎臓学会誌, 53(3) 336-336, May, 2011
多発性嚢胞腎症モデルであるjckマウスの特徴

長尾枝澄香(静子), 吉原大輔, 釘田雅則, 森田美和, 山口太美雄, WALLACE Darren

日本実験動物学会総会講演要旨集, 58th, 2011

Presentations

Polycystic Kidney Disease Association Basic Research Session (Chair)

Chair, Tamio Yamaguchi, Speaker: Toshimi Hidaka

Polycystic Kidney Disease Association 3rd PKD Conference (Naha-city, Okinawa), Dec 7, 2025
Polycystic Kidney Disease Association Young Investigator Award– Award Lecture (Chair)

Chairs: Tamio Yamaguchi, Junichi Hoshino, Awardees: Shin-Ichi Mae, Yusuke Ushio

Polycystic Kidney Disease Association 2nd PKD Conference (Juntendo University, Tokyo), Dec 1, 2024 Invited
Symposium: Approaching PKD from the Mechanistic Perspective (Chair)

Chairs: Tamio Yamaguchi, Sumi Hidaka, Invited Speakers: Yoshikatsu Kaneko, Shizuko Nagao, Keiji Shimazu, Koichi Nakanishi

Polycystic Kidney Disease Association 1st PKD Conference (Juntendo University, Tokyo), Nov 12, 2023 Invited
International Exchange and Mutual Lecture on Healthcare Professional Education between Suzuka University of Medical Science and the University of Manitoba

Tamio Yamaguchi, Harold Aukema

International Exchange and Mutual Lecture on Healthcare Professional Education, Nov 1, 2023 Invited
Exploring progression factors of nephropathy in an obesity-associated type 2 diabetes rat model

Shizuko Nagao, Tamio Yamaguchi

University of Manitoba, Canadian Centre for Agri-Food Research in Health and Medicine Seminar, Nov 1, 2023 Invited

Research Projects

Effect of equivalent caloric intake/different PFC balance diets on diabetic nephropathy and cognitive impairment

Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Apr, 2021 - Mar, 2024

Tamio YAMAGUCHI, Aya YOSHIMURA, Shizuko NAGAO
Research on the key factors and signal transduction cascades of the onset of chronic kidney disease (CKD): Application of global omics technologies.

Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Apr, 2018 - Mar, 2021

Shizuko NAGAO, Masanori KUGITA, Tamio YAMAGUCHI
Effects of diet on progression of polycystic kidney disease in animal models with the same genetic mutation as the human disease

CIHR grant, Canadian Institutes of Health Research (CIHR), May, 2011 - Apr, 2014

Harold M Aukenma, Ph.D., Tamio Yamaguchi, Ph.D. (University of Manitoba, Canada)
A novel therapeutic approach for cystic disease:Inhibition of intracellular signal transduction pathways by a nuclear receptor cascade

Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, 2010 - 2012

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Industrial Property Rights

特開特表2022-506800 特表2022-506800 身体器官または腫瘤を包むためのカプセル器具およびその使用

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