Internal Medicine

伊藤 信二

イトウ シンジ  (ito shinji)

基本情報

所属
藤田医科大学 医学部・内科学 臨床教授
学位
博士(医学)(名古屋大学)

J-GLOBAL ID
201501014100305701
researchmap会員ID
7000012806

論文

 17
  • Ito S, Kikuchi K, Ueda A, Nagao R, Maeda T, Murate K, Shima S, Mizutani Y, Niimi Y, Mutoh T
    Frontiers in neurology 9 528-528 2018年  査読有り
  • Yoshiki Niimi, Shinji Ito, Kenichiro Murate, Seiko Hirota, Chika Hikichi, Tomomasa Ishikawa, Toshiki Maeda, Ryunosuke Nagao, Sayuri Shima, Yasuaki Mizutani, Akihiro Ueda, Tatsuro Mutoh
    JOURNAL OF THE NEUROLOGICAL SCIENCES 377 174-178 2017年6月  査読有り
    Background: Although single-photon emission computerized tomography of the dopamine transporter (DATSPECT) is useful for diagnosing parkinsonian syndrome, its applicability toward the early phase of Parkinson's disease remains unknown. Methods: We enrolled 32 patients showing parkinsonism with normal cardiac I-123-metaiodobenzylguanidine (MIBG) uptake and abnormal DAT-SPECT findings among 84 consecutive patients with parkinsonism. We divided these patients into two groups (group 1: Parkinson's disease, group 2: corticobasal degeneration, progressive supranuclear palsy, multiple system atrophy), and compared their clinical characteristics, specific binding ratios, and striatal asymmetry indexes on DAT-SPECT examinations. Results: The striatal asymmetry indexes were significantly lower in group 1 than in group 2 (p < 0.05), but there were no differences in the specific binding ratios between the two groups. Conclusion: The combined use of striatal asymmetry index on DAT-SPEC' and cardiac MIBG scintigraphy might offer useful clues for the differential diagnosis of the early phase Parkinson's disease from other parkinsonian syndromes. (C) 2017 Elsevier B.V. All rights reserved.
  • Tomomasa Ishikawa, Kunihiko Asakura, Yasuaki Mizutani, Akihiro Ueda, Ken-Ichiro Murate, Chika Hikichi, Sayuri Shima, Madoka Kizawa, Masako Komori, Kazuhiro Murayama, Hiroshi Toyama, Shinji Ito, Tatsuro Mutoh
    MUSCLE & NERVE 55(4) 483-489 2017年4月  査読有り
    Introduction: To visualize peripheral nerves in patients with chronic inflammatory demyelinating polyneuropathy (CIDP), we used MR imaging. We also quantified the volumes of the brachial and lumbar plexus and their nerve roots. Methods: Thirteen patients with CIDP and 12 healthy volunteers were enrolled. Whole- body MR neurography based on diffusionweighted whole- body imaging with background body signal suppression ( DWIBS) was performed. Peripheral nerve volumes were calculated from serial axial MR images. Results: The peripheral nervous system was visualized with 3-dimensional reconstruction. Volumes ranged from 8.7 to 49.5 cm(3)/m(2) in the brachial plexus and nerve roots and from 10.2 to 53.5 cm(3)/m(2) in the lumbar plexus and nerve roots. Patients with CIDP had significantly larger volumes than controls ( P < 0.05), and volume was positively correlated with disease duration. Conclusions: MR neurography and the measurement of peripheral nerve volume are useful for diagnosing and assessing CIDP.
  • Shinji Ito, Akihiro Ueda, Kenichiro Murate, Seiko Hirota, Takao Fukui, Tomomasa Ishikawa, Sayuri Shima, Chika Hikichi, Yasuaki Mizutani, Madoka Kizawa, Kunihiko Asakura, Tatsuro Mutoh
    JOURNAL OF THE NEUROLOGICAL SCIENCES 368 344-348 2016年9月  査読有り
    Objective: Acute multifocal embolic infarction (AMEI) is conventionally caused by etiologies such as cardioembolism due to atrial fibrillation (AO, but can also be caused by serious underlying diseases such as cancer. We characterized cancer-related AMEI and identified useful indicators for cancer-associated strokes. Methods: A retrospective analysis was performed on 35 patients with Af-related AMEI and 35 patients with cancer -related AMEI selected from 1235 consecutive patients with acute infarcts. All patients received diffusion weighted magnetic resonance (MR) imaging. Cerebral MR angiography, carotid and cardiac ultrasonography, electrocardiogram-monitoring and whole body computed tomography were also performed on these patients. D-dimer levels were evaluated on admission, and were measured during the sub-acute phase in 19 of the patients with Af and 27 of the patients with cancer. Results: Acute phase D-dimer levels were significantly higher in patients with cancer than in patients with Af alone. The cut-off D-dimer value to identify cancer-associated infarcts was 2.0 mu g/mL. D-dimer levels during the sub-acute phase remained elevated in the cancer patients. Conclusions: We may differentiate cancer-associated AMEI from Af using a D-dimer level >= 2.0 mu g/mL, which does not decrease during the sub-acute phase. (C) 2016 Elsevier B.V. All rights reserved.
  • Fukui T, Ueda A, Murate K-I, Hikichi C, Ito S, Asakura K, Mutoh T
    Neurol Clin Neurosci 4(1) 31-33 2016年  査読有り

MISC

 171

書籍等出版物

 1

講演・口頭発表等

 78