研究者業績

近藤 司

kondo tsukasa

基本情報

所属
藤田保健衛生大学 医学部 医学科 救急総合内科 准教授
学位
博士(医学)

J-GLOBAL ID
201501002872269745
researchmap会員ID
7000012815

MISC

 2
  • Osuka H, Hitomi S, Oishi T, Miyamoto K, Kondo T, Urata T, Yabata E, Takei H, Funayama Y, Goto M, Koganemaru H
    General Medicine 15(1) 29-33 2014年  
  • Yoko Kurihara, Shigemi Hitomi, Tsuyoshi Oishi, Tsukasa Kondo, Tsugio Ebihara, Yasunori Funayama, Yasushi Kawakami
    JOURNAL OF INFECTION AND CHEMOTHERAPY 19(5) 799-805 2013年10月  
    Although Proteus mirabilis is a common human pathogen, bacteremia caused by the organism, especially strains producing extended-spectrum beta-lactamase (ESBL), has rarely been investigated. We examined 64 cases of P. mirabilis bacteremia identified in the Minami Ibaraki Area, Japan, between 2001 and 2010 and compared the characteristics of cases with ESBL-producing and ESBL-non-producing strains (13 and 51 cases, respectively). All ESBL-producing strains with the gene encoding the CTX-M-2-group were genetically nonidentical. Isolation of ESBL-producing strains was significantly associated with onset in a hospital (p = 0.030), receiving hemodialysis (p = 0.0050), and previous antibiotic use within 1 month (p = 0.036; especially penicillin and/or cephalosporin (p = 0.010) and fluoroquinolone (p = 0.0069)). Isolation was also associated with inappropriate antibiotic therapy on the 1st and 4th days (p = 0.011 and 0.032, respectively) but not with mortality on the 30th day. These findings indicate that, for P. mirabilis bacteremia, isolation of ESBL-producing strains causes delay of initiating appropriate antimicrobial therapy but may not be associated with mortality.

講演・口頭発表等

 12