研究者業績

中島 陽一

ナカジマ ヨウイチ  (Yoichi Nakajima)

基本情報

所属
藤田医科大学 医学部 小児科学 講師
学位
博士(医学)(2008年3月)

J-GLOBAL ID
201501006528825898
researchmap会員ID
7000012842

論文

 61
  • Hikaru Sugita, Hiroki Miura, Kazuhiro Horiba, Yoichi Nakajima, Tetsushi Yoshikawa
    Cureus 2025年2月16日  
  • 岡本 薫, 西山 里穂, 杉田 晃, 西本 早希, 河野 透哉, 杉本 えり那, 井上 博貴, 水谷 公美, 森 雄司, 大久保 悠里子, 中島 陽一, 近藤 康人, 吉川 哲史
    日本小児科学会雑誌 128(2) 205-205 2024年2月  
  • 西本 早希, 森 雄司, 杉田 晃, 水谷 公美, 近藤 康人, 河野 透哉, 杉本 えり那, 岡本 薫, 大久保 悠里子, 中島 陽一
    子どもの健康科学 25(1) 29-37 2024年1月  
  • Chisato Inuo, Hitoshi Ando, Kenichi Tanaka, Yoichi Nakajima, Ikuya Tsuge, Atsuo Urisu, Yasuto Kondo
    International archives of allergy and immunology 1-6 2023年10月18日  
    BACKGROUND: Allergen-specific immunotherapy (AIT), an established treatment for allergic diseases, prevents the development of other allergic manifestations. Although the mechanisms remain unclear, AIT has been shown to reduce basophil activation (BA) against nontarget allergens. OBJECTIVES: The aim of this study was to assess immunological changes in Dermatophagoides farinae (Der f) after Japanese cedar pollen (JCP)-based subcutaneous immunotherapy (SCIT) monotherapy. METHOD: The data of 16 patients (age: 6-37 years) with JCP-induced allergic rhinitis who were sensitive to Der f (serum Der f-specific immunoglobulin E [IgE] level >0.34 kUA/L) and received JCP-based SCIT for 5 years were reviewed retrospectively. BA by Der f and JCP extracts and serum-specific IgE and immunoglobulin G4 (IgG4) levels against these allergens were evaluated before and after completing 5 years of JCP-based SCIT monotherapy. RESULTS: The areas under the dose-response curves of BA by Der f and JCP extracts were significantly reduced (p = 0.02 and p = 0.002, respectively). JCP-specific IgE levels decreased and JCP-specific IgG4 levels increased significantly (p < 0.001 for both), whereas Der f-specific IgE and IgG4 levels did not change significantly. CONCLUSIONS: JCP-based SCIT monotherapy reduced Der f-specific BA. These findings suggest that JCP-based SCIT has the potential to modulate immune response toward nontarget allergens.
  • 森 雄司, 杉田 晃, 河野 透哉, 杉本 えり那, 西本 早希, 岡本 薫, 水谷 公美, 中島 陽一, 近藤 康人
    日本小児アレルギー学会誌 37(4) 370-370 2023年10月  

MISC

 216

書籍等出版物

 1

講演・口頭発表等

 8

共同研究・競争的資金等の研究課題

 2