koide yoshikazu

The aim of the present study was to classify the short-term outcomes of local correction of stoma prolapse with a stapler device. The medical records of 11 patients undergoing local correction of stoma prolapse using a stapler device were retrospectively reviewed. No mortality or morbidity was observed after the surgery. Median operative time was 35 min (range 15-75 min), and blood loss was minimal. Median duration of follow-up was 12 months (range 6-55 months). One of the 11 patients had a recurrent stoma prolapse. This technique can be a feasible, safe and minimally invasive correction procedure for stoma prolapse.

When performing anterior resection for rectal cancer, a robotic technique that provides three-dimensional visualization and technical dexterity has been applied to overcome some limitations of conventional laparoscopic surgery. As of the end of March 2013, 56 patients have undergone robotic colorectal surgery at Fujita Health University. We herein introduce our fully-robotic technique with single cart position and report short-term outcomes concerning 43 cases of rectal cancer. The current status and problems regarding robotic surgery for colorectal cancer in the literature are also described. Although robotic surgery for colorectal cancer has been safe and feasible, the long operative time should be shortened by utilizing the learning-curve effect.

We studied the clinicopathological characteristics of colorectal cancer with perforation in comparison with non-perforation cases, and treatment strategy for colorectal cancer with perforation. T4 cancers and cancers with massive venous invasion fell significantly into the perforation than the non-perforation group. Stage IV caner was seen more in cases with perforation than in non-perforation cases (p=0.08). The perforation occurred at the tumor site in 7 patients, at the oral site of cancer in 7, and at the anal site in 1. One-staged curative resection was performed in 5 patients, and two-staged curative resection was performed in 4. The operative time was longer, and blood loss during curative resection was more in the two-staged than in the one-staged resections. Recurrence occurred in 1 patient with stage II cancer, and in 3 patients with stage IIIa cancer. These four patients with recurrence after curative surgery had peritoneal or subcutaneous dissemination, accompanying cancer spread due to large bowel perforation. However, hematogenous or lymphatic recurrence was also seen in 4 patients including one patient who underwent a curability B resection. More lymph node dissections were seen in non-recurrence cases after curative resection (average: 19.8) than in recurrence cases (average: 6.3). It was believed that primary resection and proper lymph node dissection contributed to prevention of hematogenous or lymphatic recurrence and improvement of prognosis for the patients with large bowel perforation related to colorectal cancer.

進行大腸癌化学療法であるXELOX±BV療法の有効性・安全性を確認するための第II相臨床試験を計画した.[方法]主評価項目は奏効率,副次的評価項目は無増悪生存期間,安全性(手足症候群発生割合),治療成功期間とした.本試験では全例に対し医師,看護師,薬剤師によるチームで副作用対策に取り組んだ.この結果,副作用発現率の低下と相対的用量強度の維持に有効であったため報告する.国内I/II相試験であるJO19380試験での手足症候群(HFS)発現率はgrade2/3が17.2%/1.7%であったが当院では13.3%/0%と良好な結果であった.相対的用量強度は6コース時点でL-OHP 89.2%,Xeloda 91.0%で良好であった.またその効果はCR/PR/NC/PD割合がそれぞれ10%/56.7%/16.7%/3.3%で奏効率66.7%,病勢制御率96.7%と満足できる結果であった.[結語]今後も増加するであろう外来での抗癌剤治療では,自宅での管理がより一層重要となる.チームでの取り組みは今後更に必要になると考えられる.(著者抄録)

Stomal prolapse is one of the common complications in transverse colostomy and can be managed conservatively in most cases; however, laparotomy and reconstruction of the stoma may sometimes be required, especially in case of irreducible colostomy prolapse. We have reported a simple local repair with reconstruction of the loop colostomy. We herein report a new more simple technique to avoid laparotomy and allow excision of the irreducible colostomy prolapse and complete closure of the distal limb of loop colostomy when no decompression is required in the distal limb of the stoma. In this procedure, the number of stapler and the time with blood loss for the operation can be saved.

2009年9月に大腸癌に対するda Vinci Surgical Systemを用いたロボット手術を導入し,これまでに20例を経験した.今回は,そのなかで下部直腸癌3例に対して内括約筋切除術(ISR)を施行したので,その手技と手術成績を報告する.術前診断でcT1の2例と,経肛門的腫瘍切除(MITAS)術後の1例であり,いずれも側方郭清の必要のない症例を選択した.平均手術時間は512分,出血量は113gで,術後平均在院日数は9日であった.1例に骨盤内膿瘍を認めたが,保存的治療で軽快した.病理組織検査で,郭清リンパ節は平均17個であり,Surgical Marginも全例negativeであった.Learning curveによる手術時間の短縮とさらなる症例の蓄積によってfeasibilityと安全性を示す必要があると考えられた.(著者抄録)

Solitary fibrous tumors (SFTs) develop most commonly in the pleura, although they have occasionally been reported to arise in the pelvic cavity. We report a case of an SFT presenting as a painless nodule in the pelvis of a 56-year-old woman. Histologically, the tumor was composed of spindle-shaped cells arranged without pattern, with short and narrow fascicles and interspersed bundles of thick collagen, and numerous blood vessels with a focally hemangiopericytoma-like appearance. Immunohistochemically, the tumor cells strongly expressed vimentin, CD34, and bcl-2. The tumor was excised via a trans-sacral approach, without preoperative transcatheter embolization, and the patient remains well more than 2 years after her operation. To our knowledge, this is the first case of an SFT in the pelvis, which was excised completely via a trans-sacral approach.

11年間に経験した40歳未満の大腸癌22例を若年者大腸癌と定義し,非若年者大腸癌(40歳以上85歳未満)と比較し,若年者大腸癌の臨床病理学的特徴と治療成績向上の方策について検討した.若年者群の主訴は排便時出血が多く,平均病悩期間は9.2月であった.若年者群は女性例,リンパ管侵襲高度陽性例,N2以上のリンパ節転移陽性例,stage IIIb症例が非若年者群に比べて有意に高率であった.根治度Aの手術施行率は両群間に差を認めないものの,若年者群の再発率は非若年者群に比べて有意に高率で,stage IIIbでは有意に予後不良であった.再発形式では肺再発が有意に多かった.若年者大腸癌の予後向上のためには,排便時出血を認めた際には早期に受診するよう若年者への啓蒙に努め,できるだけ早期に癌を発見し,病期の早い段階で十分なリンパ節郭清を含めた治癒切除を行うことが重要で,術後は肺再発を意識したサーベイランスを行うことが必要と考えられた.(著者抄録)