医学部 歯科・口腔外科学

岡本 美英子

okamoto mieko

基本情報

所属
藤田医科大学 医学部 歯科・口腔外科学講座 助教
学位
博士(医学)(藤田医科大学)

J-GLOBAL ID
201501002356750879
researchmap会員ID
7000013206

論文

 10
  • Mieko Okamoto, Hiroko Tanaka, Shigeru Tamura, Daisuke Kanamori, Miyuki Yokoi, Masanobu Usui, Mitsuyoshi Yoshida
    Gerodontology 2025年8月12日  査読有り筆頭著者
    ABSTRACT Objective We aimed to examine the effects of oral care in patients with terminal cancer approaching death. Background Patients with terminal‐stage cancer often experience symptoms like oral dryness and candidiasis. Previous studies showed that without professional dental care, oral hygiene significantly worsens within 3 weeks before death. Therefore, oral management is essential for patients with terminal cancer. However, the specific effects of oral hygiene in these patients remain unclear. Material and Methods Twenty patients were admitted to two palliative care units at our institution between June 2022 and May 2023 and received oral care multiple times before death. Oral hygiene was assessed using the Oral Health Assessment Tool (OHAT), and oral dryness was evaluated with an oral moisture checker. The Face Rating Scale (FRS) was assessed before and after professional oral care. Results During the week of death, the number of people who were able to speak and follow instructions decreased, while the number who used sedatives and oxygen increased. There was no significant difference in the degree of oral dryness before oral care between the time of hospitalisation and the week of death. However, oral dryness improved significantly after oral care at admission (before: 21.0 ± 8.3, after: 26.7 ± 3.2) and the week of death (before: 16.8 ± 8.4, after: 25.8 ± 3.7). There was no difference in the time taken for oral care or FRS scores at admission and the week of death. Conclusion Continuous oral care in patients with terminal cancer can prevent worsening oral hygiene and maintain moisture.
  • Hitomi Kanie, Mitsuyoshi Yoshida, Miyuki Yokoi, Mieko Okamoto, Hitomi Sasaki, Kazuhiro Ono
    Journal of Oral Rehabilitation 2025年4月17日  
    ABSTRACT Background There is growing interest in the relationship between oral function and lifestyle‐related diseases. Objectives This study aimed to investigate the associations between the results of oral function tests and those of blood tests for lipid abnormalities, glucose metabolism and kidney function. Methods A total of 118 individuals aged ≥ 50 years (80 men and 38 women) who had undergone health check‐ups at our hospital in 2021 and 2023 were examined. Based on the fasting blood glucose (GLU), HbA1c, high‐density lipoproteins (HDL), low‐density lipoproteins (LDL), urea nitrogen (BUN) and estimated glomerular filtration rate (eGFR) values obtained from the health check‐up results; the subjects were divided into two groups: those with test values outside the reference range in 2021 and/or 2023 and those with test values within the reference range. The results of seven oral function tests were compared between the groups using the Mann–Whitney U test. p < 0.05 was considered significant. Results The group with GLU and HbA1c values outside the reference ranges had significantly lower numbers of remaining teeth (RTN) and oral diadochokinesis (OD) values compared to the group within the reference range. The groups with HDL and LDL values outside the standard ranges had a significantly higher tongue coat index (TCI) and significantly lower OD. Significant differences in TCI and OD/ta/ /ka/ were observed between BUN groups within and outside the reference range. Likewise, significant differences in TCI, RTN and OD/ta/ /ka/ were observed between eGFR groups within and outside the reference range. Conclusions Subjects with blood test values outside the reference range exhibited a decline in oral function, indicating that a decline in oral function might increase the risk of lifestyle‐related diseases and facilitate the progression of frailty.
  • Mieko Okamoto, Mitsuyoshi Yoshida, Kazuhiro Tsuga, Koichiro Matsuo, Kazunori Ikebe, Takayuki Ueda, Shunsuke Minakuchi
    Gerodontology 42(1) 52-60 2024年6月14日  査読有り筆頭著者
    Introduction Oral hypofunction comprises seven aspects of oral condition, including oral hygiene, oral dryness, bite strength, tongue‐lip motor function, tongue pressure, masticatory function, and swallowing function. Each of these seven has a single diagnostic criterion; however, the use of a single indicator without consideration of sex, age, or other factors is controversial. The purpose of this study was to evaluate the association between the oral hypofunction test and sex, age, and number of remaining teeth. Methods The study was conducted at 12 facilities by the members of the Japanese Society of Geriatric Dentistry during April to December 2019. The participants comprised 181 healthy older adults aged 65 years and over (56.9% female; age range 65–95 years) who regularly visited these facilities. All tests of oral function and oral status available in Japan were performed on the participants, and the association between these tests and sex, age, and number of remaining teeth was examined. Results Sex differences were observed in masticatory function, bite force, lip closure force, jaw‐opening force, oral diadochokinesis “ka,” and tongue coating index (p < .05). In men, age was weakly (r = 0.20–0.40) associated with masticatory function, jaw‐opening force, maximum tongue pressure, oral diadochokinesis, and swallowing function. In women, the number of remaining teeth, masticatory function, jaw‐opening force, and oral diadochokinesis “ta” and “ka” was also weakly associated with age. Conclusions Performance on the oral hypofunction test differs by sex, age, and number of remaining teeth. This means that the current single criterion for evaluation requires caution in its interpretation.
  • Mieko Okamoto, Mitsuyoshi Yoshida, Daisuke Kanamori, Yoshikazu Kobayashi, Yasumichi Nakajima, Miyo Murai, Masanobu Usui
    Annals of Palliative Medicine 13(1) 42-48 2024年1月  査読有り筆頭著者
  • Koichiro Matsuo, Yu Sekimoto, Mieko Okamoto, Seiko Shibata, Yohei Otaka
    Gerodontology 39(1) 67-73 2021年8月26日  査読有り
    Abstract Background Stroke patients often suffer from dysphagia during their recovery. We hypothesised that subacute stroke patients with dysphagia had more deteriorated oral health status including muscle strength and motor function. Objective Quantitatively investigate oral health status and identify associations with oral feeding status in stroke patients admitted to a convalescent rehabilitation unit. Methods We prospectively recruited 187 stroke patients admitted to a convalescent rehabilitation unit. Oral feeding status was examined using the Functional Oral Intake Scale (FOIS), and the cohort was divided into three groups based on FOIS score as non‐oral feeding (FOIS‐123; 22 patients), dysphagic diet (FOIS‐45; 74 patients), and regular diet (FOIS‐67; 91 patients) groups. Activities of daily living (ADL) were assessed with the Functional Independence Measure (FIM). Oral health status was measured quantitatively in six oral function parameters and Oral Health Assessment Tool (OHAT), and differences according to the FOIS, age and FIM were statistically tested. Results In bivariate analysis, two parameters, tongue pressure and tongue‐lip motor functions were significantly higher in the regular diet group than in the other groups (P < .01). Gross OHAT score was also significantly better in the regular diet group than in the other groups (P < .01). These significant associations mostly remained in the multiple model after adjusting for age and FIM. Conclusion This study suggests that, amongst oral health status, tongue strength and motor function, as well as OHAT score, may have strong associations with oral feeding status in subacute stroke patients at convalescent rehabilitation units regardless of ADL levels.

MISC

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講演・口頭発表等

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