医学部 内科学(岡崎医療センター)

中村 正克

ナカムラ マサカツ  (Masakatsu Nakamura)

基本情報

所属
藤田医科大学 消化器内科 准教授
金沢医科大学 消化器内科 臨床教授
学位
博士(医学)

研究者番号
90623116
J-GLOBAL ID
202001018194324149
researchmap会員ID
R000013734

研究キーワード

 2

論文

 164
  • Noriyuki Nakajima, Toshihisa Takeuchi, Ryota Hokari, Kazuyuki Narimatsu, Katsunori Iijima, Shigeto Koizumi, Kunio Kasugai, Masahide Ebi, Akihito Nagahara, Tsutomu Takeda, Toshihiko Tomita, Shinichiro Shinzaki, Kazuhiro Mizukami, Kazunari Murakami, Nobuaki Yagi, Rieko Mukai, Toshikatsu Okumura, Hiroki Tanabe, Kazuyuki Tanaka, Junichi Iwamoto, Atsushi Irisawa, Koh Fukushi, Hiromi Kataoka, Hirotada Nishie, Yasuhiro Fujiwara, Koji Otani, Osamu Handa, Yasuhiko Maruyama, Toshio Uraoka, Hiroko Hosaka, Takahisa Furuta, Tomohisa Takagi, Masakatsu Nakamura, Yuya Nyumura, Akitoshi Hakoda, Noriaki Sugawara, Taro Iwatubo, Kazuhiro Ota, Shinpei Kawaguchi, Kazuhide Higuchi, Hiroki Nishikawa
    Journal of clinical biochemistry and nutrition 74(1) 82-89 2024年1月  
    This study investigated the trends in idiopathic peptic ulcers, examined the characteristics of refractory idiopathic peptic ulcer, and identified the optimal treatment. The characteristics of 309 patients with idiopathic peptic ulcer were examined. We allocated idiopathic peptic ulcers that did not heal after 8 weeks' treatment (6 weeks for duodenal ulcers) to the refractory group and those that healed within this period to the healed group. The typical risk factors for idiopathic peptic ulcer (atherosclerosis-related underlying disease or liver cirrhosis complications) were absent in 46.6% of patients. Absence of gastric mucosal atrophy (refractory group: 51.4%, healed group: 28.4%; p = 0.016), and gastric fundic gland polyps (refractory group: 17.6%, healed group: 5.9%; p = 0.045) were significantly more common in the refractory group compared to the healed group. A history of H. pylori eradication (refractory group: 85.3%, healed group: 66.0%; p = 0.016), previous H. pylori infection (i.e., gastric mucosal atrophy or history of H. pylori eradication) (refractory group: 48.5%, healed group: 80.0%; p = 0.001), and potassium-competitive acid blocker treatment (refractory group: 28.6%, healed group, 64.1%; p = 0.001) were significantly more frequent in the healed group compared to the refractory group. Thus, acid hypersecretion may be a major factor underlying the refractoriness of idiopathic peptic ulcer.
  • Tomoyuki Shibata, Keishi Koyama, Hyuga Yamada, Tomohiko Kawamura, Dai Yoshida, Hayato Osaki, Noriyuki Horiguchi, Kohei Funasaka, Ryoji Miyahara, Mitsuo Nagasaka, Yoshihito Nakagawa, Senju Hashimoto, Tomomitsu Tahara, Masakatsu Nakamura, Tomiyasu Arisawa, Yoshiki Hirooka
    Internal medicine (Tokyo, Japan) 2023年1月12日  
    Objective In general, surface ulceration in gastric gastrointestinal stromal tumor (GIST) is considered a malignant feature; however, the mechanism underlying its formation has not been evaluated in detail. In this study, we analyzed the factors involved in ulceration using resected specimens of gastric GIST. Methods A total of 48 samples were retrospectively analyzed. We examined the association of surface ulceration of gastric GIST with the MIB-1 labeling index, mitotic number, tumor size, endoscopic ultrasound (EUS) findings and growth pattern on computed tomography (CT). Results The proportion of men was significantly higher in the ulceration group than in the non-ulceration group (p=0.04146), whereas age was not significantly different between the groups. Tumor was significantly larger in the ulceration group than in the non-ulceration group (p=0.0048). There was no correlation between tumor size and ulcer number. The MIB-1 index was not related to ulceration, nor were EUS findings. The number of mitotic cells tended to be higher in the ulceration group than in the non-ulceration group (p=0.05988). Intraluminal growth pattern was strongly associated with ulceration (p=0.00019). After a multivariate analysis, the growth pattern was the only factor associated with ulceration of gastric GIST. Conclusion Although formation of surface ulceration in gastric GIST was partially associated with the degree of malignancy, the growth pattern was the most important factor associated with ulceration in gastric GIST.
  • Masakatsu Nakamura, Toshimi Otsuka, Motona Kumagai, Tomiyasu Arisawa
    Internal medicine (Tokyo, Japan) 61(2) 267-269 2021年7月10日  
  • Masakatsu Nakamura, Toshimi Otsuka, Ranji Hayashi, Tomoe Horita, Masafumi Ota, Naoko Sakurai, Hikaru Takano, Tasuku Hayashi, Seiko Miura, Nobuhiko Ueda, Hiroyuki Takamura, Tomiyasu Arisawa
    Clinical journal of gastroenterology 14(4) 1255-1262 2021年5月18日  
    We encountered three cases with incidental penetration of a straight Amsterdam-type bile duct plastic stent into the duodenal papilla. All patients had undergone insertion of a biliary plastic stent due to common bile duct stones. However, in all three cases, we observed penetration of the biliary plastic stent into the duodenal papilla just before the elective surgery or at the time of plastic stent replacement. We, therefore, performed stent dissection using a bipolar snare and were able to safely remove the plastic stents in all three cases. We believe that this is the first report of plastic stent dissection using a bipolar snare.
  • Tasuku Hayashi, Tomoyuki Shibata, Masakatsu Nakamura, Naoko Sakurai, Hikaru Takano, Masafumi Ota, Tomoe Nomura-Horita, Ranji Hayashi, Takeo Shimasaki, Toshimi Ostuka, Tomomitsu Tahara, Tomiyasu Arisawa
    GENETIC TESTING ANDMOLECULAR BIOMARKERS 25 255-262 2021年  査読有り

MISC

 193

書籍等出版物

 1

講演・口頭発表等

 125