Nao Hirata

(平田直)

Profile Information

Affiliation: Institute for Comprehensive Medical Science, Fujita Health University

J-GLOBAL ID: 201601006928865411
researchmap Member ID: B000267061

Research Interests

バイオイメージング

Research Areas

Nanotechnology/Materials / Biochemistry /

Research History

Aug, 2016 - Present

博士研究員, システム医科学研究部門, 藤田保健衛生大学総合医科学研究所
Jun, 2015 - Jul, 2016

研究補助員, システム医科学研究部門, 藤田保健衛生大学総合医科学研究所
Apr, 2011 - Oct, 2013

博士研究員（最先端・次世代研究）, ケミカルバイオロジー研究室, 京都大学物質‐細胞統合システム拠点
Apr, 2009 - Mar, 2011

Institute for Chemical Research, Kyoto University

Education

Apr, 2006 - Mar, 2009

Kyoto University
Apr, 2004 - Mar, 2006

Kyoto University
Apr, 2000 - Mar, 2004

School of Industrial Chemistry, Faculty of Engineering, Kyoto University

Papers

Selective Elimination of Human Pluripotent Stem Cells by a Marine Natural Product Derivative

Ting-Fang Kuo, Di Mao, Nao Hirata, Bilon Khambu, Yasuhisa Kimura, Eihachiro Kawase, Hiroki Shimogawa, Makoto Ojika, Norio Nakatsuji, Kazumitsu Ueda, Motonari Uesugi

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 136(28) 9798-9801, Jul, 2014 Peer-reviewed
A Chemical Probe that Labels Human Pluripotent Stem Cells

Nao Hirata, Masato Nakagawa, Yuto Fujibayashi, Kaori Yamauchi, Asako Murata, Itsunari Minami, Maiko Tomioka, Takayuki Kondo, Ting-Fang Kuo, Hiroshi Endo, Haruhisa Inoue, Shin-ichi Sato, Shin Ando, Yoshinori Kawazoe, Kazuhiro Aiba, Koh Nagata, Eihachiro Kawase, Young-Tae Chang, Hirofumi Suemori, Koji Eto, Hiromitsu Nakauchi, Shinya Yamanaka, Norio Nakatsuji, Kazumitsu Ueda, Motonari Uesugi

CELL REPORTS, 6(6) 1165-1174, Mar, 2014 Peer-reviewed
Preparation and fluorescence properties of fluorophore-labeled avidin-biotin system immobilized on Fe3O4 nanoparticles through functional indolequinone linker

Nao Hirata, Kazuhito Tanabe, Asako Narita, Kazuo Tanaka, Kensuke Naka, Yoshiki Chujo, Sei-ichi Nishimoto

BIOORGANIC & MEDICINAL CHEMISTRY, 17(11) 3775-3781, Jun, 2009 Peer-reviewed
Radiolytic activation of a cytarabine prodrug possessing a 2-oxoalkyl group: one-electron reduction and cytotoxicity characteristics

Nao Hirata, Yusuke Fujisawa, Kazuhito Tanabe, Hiroshi Harada, Masahiro Hiraoka, Sei-ichi Nishimoto

ORGANIC & BIOMOLECULAR CHEMISTRY, 7(4) 651-654, 2009 Peer-reviewed
Radiolytic one-electron reduction characteristics of tyrosine derivative caged by 2-oxopropyl group

Kazuhito Tanabe, Masahiko Ebihara, Nao Hirata, Sei-ichi Nishimoto

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 18(23) 6126-6129, Dec, 2008 Peer-reviewed
Emission under hypoxia: One-electron reduction and fluorescence characteristics of an indolequinone-coumarin conjugate

Kazuhito Tanabe, Nao Hirata, Hiroshi Harada, Masahiro Hiraoka, Sei-ichi Nishimoto

CHEMBIOCHEM, 9(3) 426-432, Jan, 2008 Peer-reviewed
One-Electron Reduction Characteristics of Indolequinone-Coumarin Conjugate as Hypoxia Imaging Probe

Tanabe, K, Hirata, N, Harada, H, Hiraoka, M, Nishimoto, S

Photomedicine and Photobiology, 29 23-24, 2007
Regulation of DNA Duplex Formation by Hypoxic Irradiation: One-Electron Reduction Characteristics of Oligodeoxynucleotides Possessing 2-Oxoalkyl Functional Group

Tanabe, K, Kanezaki, H, Hirata, N, Goto, M, Nishimoto, S

Nucleic Acids Symposium Series, 50 83-84, 2006

Books and Other Publications

実験医学

竹本尚弘, 平田直, 上杉志成 (Role: Joint author, 細胞治療を助ける小分子合成化合物)

羊土社, 2012
蛍光イメージング/MRIプローブの開発

平田直, 上杉志成 (Role: Joint author, 第16章幹細胞を可視化する蛍光小分子化合物)

シーエムシー出版, 2011

Research Projects

ガンを誘発する未分化iPS細胞を特異的に認識して除去するための分子システムの開発

科学研究費補助金（若手研究B）, Apr, 2011 - Mar, 2013

平田直
Development of a fluorescent small-molecule probe for detecting and removing undifferentiated stem cells

The iCeMS Exploratory Grants, 2011 - 2011

Nao Hirata

Industrial Property Rights

特願61/584,110 Method for sorting of pluripotent cells
特願2007-77036 標的部位で選択的に蛍光強度が強くなる新規化合物および画像診断用組成物

西本清一, 田邉一仁, 平田直, 八田博司

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