Mitsuyasu Itoh

(伊藤光泰)

Profile Information

Affiliation: Professor of Medicine, School of Medicine, Faculty of Medicine, Fujita Health University

Degree: (BLANK)

J-GLOBAL ID: 200901010157792273
researchmap Member ID: 1000049261

Research Interests

Research Areas

Life sciences / Metabolism and endocrinology /

Education

- 1978

Nagoya University
- 1978

Graduate School, Division of Medicine, Nagoya University
- 1974

School of Medicine, Nagoya University
- 1974

Faculty of Medicine, Nagoya University

Awards

Nov, 2011

Miyake Prize, The Japan Thyroid Association

ITOH Mitsuyasu

Papers

Oral alendronate can suppress bone turnover but not fracture in kidney transplantation recipients with hyperparathyroidism and chronic kidney disease

Sakura Yamamoto, Atsushi Suzuki, Hitomi Sasaki, Sahoko Sekiguchi-Ueda, Shogo Asano, Megumi Shibata, Nobuki Hayakawa, Shuji Hashimoto, Kiyotaka Hoshinaga, Mitsuyasu Itoh

JOURNAL OF BONE AND MINERAL METABOLISM, 31(1) 116-122, Jan, 2013 Peer-reviewed
Effects of aripiprazole and clozapine on the treatment of glycolytic carbon in PC12 cells

Akira Ota, Akira Nakashima, Yoko S. Kaneko, Keiji Mori, Hiroshi Nagasaki, Takeshi Takayanagi, Mitsuyasu Itoh, Kazunao Kondo, Toshiharu Nagatsu, Miyuki Ota

JOURNAL OF NEURAL TRANSMISSION, 119(11) 1327-1342, Nov, 2012 Peer-reviewed
Some fine-structural findings on the thyroid gland in Apc (1638T/1638T) mice that express a C-terminus lacking truncated Apc

Atsushi Yokoyama, Ryuji Nomura, Masafumi Kurosumi, Atsushi Shimomura, Takanori Onouchi, Akiko Iizuka-Kogo, Ron Smits, Riccardo Fodde, Mitsuyasu Itoh, Takao Senda

MEDICAL MOLECULAR MORPHOLOGY, 45(3) 161-167, Sep, 2012 Peer-reviewed
Relative Levels of the Inflammatory Cytokine TNF alpha and the Soluble CD40 Ligand Profile in Serum Correlate with the Thyrotoxic Activity of Graves' Disease

Keiko Yamamoto, Mitsuyasu Itoh, Tomoko Okamura, Maiko Kimura, Atsushi Yokoyama, Yasumasa Yoshino, Masaki Makino, Nobuki Hayakawa, Atsushi Suzuki

THYROID, 22(5) 516-521, May, 2012 Peer-reviewed
Use of a new high-sensitivity assay for cardiac troponin T to stratify the risk of cardiovascular disease in outpatients with type-2 diabetes

Shogo Asano, Atsushi Suzuki, Junnichi Ishii, Sahoko Sekiguchi-Ueda, Megumi Shibata, Yasumasa Yoshino, Kazuhiro Nakamura, Yasukazu Akiyama, Fumihiko Kitagawa, Toshiaki Sakuishi, Takashi Fujita, Mitsuyasu Itoh

Diabetology International, 3(1) 29-36, Mar, 2012 Peer-reviewed

Misc.

Changes in cyclic nucleotide phosphodiesterase activity and calmodulin concentration in heart muscle of cardiomyopathic hamsters

R Masunaga, A Nagasaka, Y Sawai, N Hayakawa, A Nakai, K Hotta, Y Kato, H Hishida, H Takahashi, M Naka, Y Shimada, T Tanaka, H Hidaka, M Itoh

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 37(3) 767-774, Sep, 2004
A stable prostacyclin analogue reduces high serum TNF-alpha levels in diabetic patients

K Fujiwara, A Nagasaka, M Nagata, K Yamamoto, S Imamura, N Oda, Y Sawai, N Hayakawa, A Suzuki, M Itoh

EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES, 112(7) 390-394, Jul, 2004
Possible involvement of p38 MAP kinase in prostaglandin E1-induced ALP activity in osteoblast-like cells

A Kakita, A Suzuki, Y Ono, Y Miura, M Itoh, Y Oiso

PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS, 70(5) 469-474, May, 2004
Stimulation of Na-dependent phosphate transport by platelet-derived growth factor in rat aortic smooth muscle cells

A Kakita, A Suzuki, K Nishiwaki, Y Ono, M Kotake, Y Ariyoshi, Y Miura, M Itoh, Y Oiso

ATHEROSCLEROSIS, 174(1) 17-24, May, 2004
Tetrahydrobiopterin biosynthesis in white and brown adipose tissues is enhanced following intraperitoneal administration of bacterial lipopolysaccharide

K Fujiwara, K Mori, YS Kaneko, A Nakashima, A Nagasaka, M Itoh, A Ota

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1670(3) 181-198, Feb, 2004
Alteration of urinary sorbitol excretion in WBN-Kob diabetic rats-treatment with an aldose reductase inhibitor.‘jointly worked’

Journal of Endocrinology, 181, 429-435, 2004
Possible role of VEGF in the progression of kidney disease in streptozotocin (STZ)-induced diabetic rats: Effects of an ACE inhibitor and an angiotensin II receptor antagonist.‘jointly worked’

Hormone and Metabolic Research, 36, 453-457, 2004
Expression of erb B receptors mRNA in thyroid tissues.‘jointly worked’

Biochimica et Biophysica Acta, 1673, 194-200, 2004
The rationship between glycemic control and plasma vascular endothelial growth factor and endothelin-1 concentration in diabetic patients.‘jointly worked’

Metabolism, 53(5), 550-555, 2004
Urinary sorbitol measurement and the effect of an aldose reductase inhibitor on its concentration in the diabetic state

Nakano, I, T Tsugawa, R Shinohara, F Watanabe, T Fujita, M Nagata, T Kato, Y Himeno, T Kobayashi, K Fujiwara, M Nagata, M Itoh, A Nagasaka

JOURNAL OF DIABETES AND ITS COMPLICATIONS, 17(6) 337-342, Nov, 2003
Stimulatory effect of prostaglandin F-2 alpha on Na-dependent phosphate transport in osteoblast-like cells

Sato, I, A Suzuki, A Kakita, Y Ono, Y Miura, M Itoh, Y Oiso

PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS, 68(5) 311-315, May, 2003
cGMP inhibits GTP cyclohydrolase I activity and biosynthesis of tetrahydrobiopterin in human umbilical vein endothelial cells.‘jointly worked’

Journal of Pharmacological Sciences, 93, 265-271, 2003
Genetic variations in calpain-10 gene are not a major factor in the occurrence of type 2 diabetes in Japanese

Y Horikawa, N Oda, L Yu, S Imamura, K Fujiwara, M Makino, Y Seino, M Itoh, J Takeda

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 88(1) 244-247, Jan, 2003
Distinctive response of thyroid-infiltrating mononuclear cells to B cell activation through CD40 and interleukin-4 in Graves' patients

M Itoh, K Uchimura, K Yamamoto, M Makino, S Imamura, T Kobayashi, K Fujiwara, T Kato, N Hayakawa, Y Sawai, A Nagasaka, K Iwase, T Nomura, Y Hagino

CYTOKINE, 19(3) 107-114, Aug, 2002
Peripheral injection of resperidone, an atypical antipsychotic, alters the body weight gain of rats.‘jointly worked’

Clinical & Experimental Pharmacology & Physiology, 29(11), 980-989, 2002
Changes of endothelin in streptozotocin-induced diabetic rats: effects of an angiotensin converting enzyme inhibitor, enalapril maleate.‘jointly worked’

Journal of endocrinology, 175(1), 233-239, 2002
A Calcium-Deficient Diet Caused Decreased Bone Mineral Density and Secondary Elevation of Estrogen in Aged Male Rats-Effect of Menatetrenone and Elcatonin.‘jointly worked’

Metabolism, 51(10), 1230-1234, 2002
Hormonal regulation of DNA polymerase β activity and expression in rat adrenal glands and testes.‘jointly worked’

Molecular and Cellular Endocrinology, 192, 127-132, 2002
Lung Cancer Associated with Hypercalcemia Induced by Concurrently Elevated Parathyroid Hormone and Parathyroid Hormone-Related Protein Levels.‘jointly worked’

Metabolism, 51(7), 871-875, 2002
The effects of CD40- and interleukin (IL-4)-activated CD23+ cells on the production of IL-10 by mononuclear cells in Graves' disease: the role of CD8+ cells.‘jointly worked’

Clinical & Experimental Immunology, 128, 308-312, 2002
CAMP inhibits cytokine-induced biosynthesis of tetrahydrobiopterin in human umbilical vein endothelial cells ‘jointly worked’

Life Sciences, 70, 2187-2198, 2002
Alteration of Endothelin-1 concentration in STZ-induced Diabetic Rat Nephropathy‘jointly worked’

Hormone Research, 56, 165-171, 2001
Effect of eicosapentaenoic acid ethyl ester on hypothyroid function‘jointly worked’

Journal of Endocrinology, 171, 259-265, 2001
The therapeutic effect of Lipo PGE, on diabetic nearopathy - changes in endothelin and various angiopathic factors‘jointly worked’

Prostaglandins & Other Lipid Mediators, 66, 221-234, 2001
Polymorphisms of the Insulin Gene Among Japanese Subjects‘jointly worked’

Metabolism, 50(6), 631-634, 2001
Production of IL-10 and IL-12 in CD40 and interleukin 4-activated mononuclear cells from patients with Graves'disease.‘jointly worked’

Cytokine, 12(6) 688-693, 2000
Scavenging effect of nicorandil on free radicals and lipid peroxide in streptozotocin-induced diabetic rats

Toshiki Mano, Rikio Shinohara, Akio Nagasaka, Hifumi Nakagawa, Keiko Uchimura, Ritsuko Hayashi, Itsuko Nakano, Toru Tsugawa, Fumiko Watanabe, Takako Kobayashi, Kentaro Fujiwara, Akira Nakai, Mitsuyasu Itoh

Metabolism: Clinical and Experimental, 49(4) 427-431, 2000
Lipid peroxidation levels in rat cardiac muscle are affected by age and thyroid status‘jointly worked’

Journal of Endocrinology, 164 97-102, 2000
Changes in superoxide dismutase activities and concentrations and myeloperoxidase activities in leukocytes from patients with diabetes mellitus

K Uchimura, A Nagasaka, R Hayashi, M Makino, M Nagata, H Kakizawa, T Kobayashi, K Fujiwara, T Kato, K Iwase, R Shinohara, K Kato, M Itoh

JOURNAL OF DIABETES AND ITS COMPLICATIONS, 13(5-6) 264-270, Sep, 1999
Glucose transporter 2 concentrations in hyper- and hypothyroid rat livers

T Mokuno, K Uchimura, R Hayashi, N Hayakawa, M Makino, M Nagata, H Kakizawa, Y Sawai, M Kotake, N Oda, A Nakai, A Nagasaka, M Itoh

JOURNAL OF ENDOCRINOLOGY, 160(2) 285-289, Feb, 1999
Accelerated conversion of dehydroepiandrosterone sulfate to estrogen in a patient with Crow-Fukase syndrome and diabetes mellitus

T Mano, K Mori, Y Sawai, N Oda, T Tugawa, Nakano, I, F Watanabe, M Hamada, P Nakai, H Yamamoto, N Harada, A Nagasaka, M Itoh

ENDOCRINE RESEARCH, 25(3-4) 371-380, 1999
Increased urinary phosphate excretion in pseudohypoparathyroidism type (]G0002[) with long-term treatment with phosphodiesterase in hibitor‘jointly worked’

Hormone and Metabolic Research, 31 602-605, 1999
Hypersensitivity to regular and intermediate, but not to crystallized, insulin as an aggravation factor for underlying bulimia nervosa in a patient with type 1 diabetes‘jointly worked’

Diabetes Care, 22(7) 1221-1224, 1999
Effects of thyroid hormone on the sorbitol pathway in streptozotocin-induced diabetic rats

R Shinohara, T Mano, A Nagasaka, Y Sawai, K Uchimura, R Hayashi, N Hayakawa, M Nagata, M Makino, H Kakizawa, Y Itoh, A Nakai, M Itoh

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1425(3) 577-586, Nov, 1998
Surface expression and release of soluble forms of CD8 and CD23 in CD40- and IL-4-activated mononuclear cells from patients with Graves' disease (GD)

M Itoh, K Uchimura, N Hayakawa, M Makino, R Hayashi, M Nagata, H Kakizawa, A Nagasaka, H Sakamoto, H Kuzuya

CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 113(2) 309-314, Aug, 1998
Vitamin E and coenzyme Q concentrations in the thyroid tissues of patients with various thyroid disorders

T Mano, K Iwase, R Hayashi, N Hayakawa, K Uchimura, M Makino, M Nagata, Y Sawai, N Oda, M Hamada, T Aono, A Nakai, A Nagasaka, M Itoh

AMERICAN JOURNAL OF THE MEDICAL SCIENCES, 315(4) 230-232, Apr, 1998
Effects of thyroid hormone on catecholamine and its metabolite concentrations in rat cardiac muscle and cerebral cortex

T Mano, H Sakamoto, K Fujita, M Makino, H Kakizawa, M Nagata, M Kotake, M Hamada, K Uchimura, N Hayakawa, R Hayashi, A Nakai, M Itoh, H Kuzuya, A Nagasaka

THYROID, 8(4) 353-358, Apr, 1998
Changes in erythrocyte sorbitol concentrations measured using an improved assay system in patients with diabetic complications and treated with aldose reductase inhibitor

R Hayashi, N Hayakawa, M Makino, M Nagata, H Kakizawa, K Uchimura, M Hamada, T Aono, T Fujita, R Shinohara, A Nagasaka, M Itoh

DIABETES CARE, 21(4) 672-673, Apr, 1998
Utility of measuring serum parathyroid hormone-related protein concentration in leukemic patients with hypercalcemia for assessing disease status(共著)

European Journal of Endocrinology, 139(3) 323-329, 1998
Reduction of Activity, but no Decrease in Concentration, of Erythrocyte Cu, Zn-superoxide Dismutase by Hyperglycaemia in Diabetic Patients (共著)

Diabetic Medicine, 15(8) 668-671, 1998
Relations between surface expression of the interleukin-2 receptor and release of the soluble form of the receptor in cultured mononuclear cells from patients with rheumatoid arthritis or systemic lupus erythematosus

M Itoh, Y Goto, Y Ohta, Y Goto, H Ohashi

CLINICAL RHEUMATOLOGY, 17(1) 26-30, 1998
Recombinant human TSH receptor expressed in E-coli

A Nakai, Y Sawai, K Miura, N Oda, T Mokuno, K Shimazaki, R Kato, N Hayakawa, M Itoh, Y Kurosawa, A Nagasaka

CLINICA CHIMICA ACTA, 263(1) 15-23, Jul, 1997
Increased production of B-cell growth factor by T lymphocytes in Graves' thyroid : Possible role of CD₄⁺CD₂₉⁺ cells‘jointly worked’

THYROID, 7(4) 567-573, 1997
Pulmonary thromboembolism in a patient with idiopathic hypereosinophilic syndrome‘jointly worked’

Japanese Journal of Rheumatology, 7(2) 115-121, 1997
A case of myocarditis associated with IDDM

T Mokuno, Y Sawai, N Oda, T Mano, N Hayakawa, R Kato, Y Itoh, K Shimazaki, M Kotake, A Nakai, S Hiramitsu, M Itoh, S Morimoto, A Nagasaka

DIABETES CARE, 19(4) 375-378, Apr, 1996
Short stature due to growth hormone deficiency associated with Cushing's disease and ulcerative colitis‘jointly worked’

Hormone and Metabolic Research, 28(10) 565-569, 1996
Increased production of B cell growth factor(BCGF) in Sjögren's syndrome‘jointly worked’

Journal of Autoimmunity, 9(4) 545-550, 1996
Decreased secretion of gonadotropins in a patient with Graves' disease

M Hakamata, M Itoh, Y Sudo, E Katada, N Miyata

EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES, 104(1) 85-88, 1996
DEXAMETHASONE-INDUCED CHANGES IN GLUCOSE-TRANSPORTER-4 IN RAT-HEART MUSCLE, SKELETAL-MUSCLE AND ADIPOCYTES

N ODA, A NAKAI, T MOKUNO, Y SAWAI, Y NISHIDA, T MANO, K ASANO, Y ITOH, M KOTAKE, S KATO, R MASUNAGA, K IWASE, T TSUJIMURA, M ITOH, T KAWABE, A NAGASAKA

EUROPEAN JOURNAL OF ENDOCRINOLOGY, 133(1) 121-126, Jul, 1995
EFFECT OF APHIDICOLIN ON DNA-SYNTHESIS IN CULTURED HUMAN THYROID-CELLS

T OKUGAWA, M ITOH, Y MURATA, H SEO

EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES, 103(2) 88-93, 1995

Books and Other Publications

Fructosamine as an Index of Glycemic Control and its Relationships to Diabetic Complications‘jointly worked’

The Organizing Committee : 'Glycated Proteins in Diabetes Mellitus' Symposium 1988, 1990
Iodide potentiates a growth-promoting activity of Epidermal growth factor in human thyroid cells in monolayer culture(共著)

Elsevier Science Publishers "The thyroid 1988", 1988
Lymphoblastogenesis to Specific Antigens and the Role of Monocytes in Diabetes with Positive Islet Cell Surface Antibodies (ICSA) In : Best approach to the ideal therapy of diabetes mellitus‘jointly worked’

Elsevies Science Publishers BV, 1987
Secretion of Glucagon In : The Islets of Langerhans‘jointly worked’

Academic Press, 1981

Professional Memberships

Research Projects

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