masumori koji

The aim of the present study was to classify the short-term outcomes of local correction of stoma prolapse with a stapler device. The medical records of 11 patients undergoing local correction of stoma prolapse using a stapler device were retrospectively reviewed. No mortality or morbidity was observed after the surgery. Median operative time was 35 min (range 15-75 min), and blood loss was minimal. Median duration of follow-up was 12 months (range 6-55 months). One of the 11 patients had a recurrent stoma prolapse. This technique can be a feasible, safe and minimally invasive correction procedure for stoma prolapse.

When performing anterior resection for rectal cancer, a robotic technique that provides three-dimensional visualization and technical dexterity has been applied to overcome some limitations of conventional laparoscopic surgery. As of the end of March 2013, 56 patients have undergone robotic colorectal surgery at Fujita Health University. We herein introduce our fully-robotic technique with single cart position and report short-term outcomes concerning 43 cases of rectal cancer. The current status and problems regarding robotic surgery for colorectal cancer in the literature are also described. Although robotic surgery for colorectal cancer has been safe and feasible, the long operative time should be shortened by utilizing the learning-curve effect.

We studied the clinicopathological characteristics of colorectal cancer with perforation in comparison with non-perforation cases, and treatment strategy for colorectal cancer with perforation. T4 cancers and cancers with massive venous invasion fell significantly into the perforation than the non-perforation group. Stage IV caner was seen more in cases with perforation than in non-perforation cases (p=0.08). The perforation occurred at the tumor site in 7 patients, at the oral site of cancer in 7, and at the anal site in 1. One-staged curative resection was performed in 5 patients, and two-staged curative resection was performed in 4. The operative time was longer, and blood loss during curative resection was more in the two-staged than in the one-staged resections. Recurrence occurred in 1 patient with stage II cancer, and in 3 patients with stage IIIa cancer. These four patients with recurrence after curative surgery had peritoneal or subcutaneous dissemination, accompanying cancer spread due to large bowel perforation. However, hematogenous or lymphatic recurrence was also seen in 4 patients including one patient who underwent a curability B resection. More lymph node dissections were seen in non-recurrence cases after curative resection (average: 19.8) than in recurrence cases (average: 6.3). It was believed that primary resection and proper lymph node dissection contributed to prevention of hematogenous or lymphatic recurrence and improvement of prognosis for the patients with large bowel perforation related to colorectal cancer.

進行大腸癌化学療法であるXELOX±BV療法の有効性・安全性を確認するための第II相臨床試験を計画した.[方法]主評価項目は奏効率,副次的評価項目は無増悪生存期間,安全性(手足症候群発生割合),治療成功期間とした.本試験では全例に対し医師,看護師,薬剤師によるチームで副作用対策に取り組んだ.この結果,副作用発現率の低下と相対的用量強度の維持に有効であったため報告する.国内I/II相試験であるJO19380試験での手足症候群(HFS)発現率はgrade2/3が17.2%/1.7%であったが当院では13.3%/0%と良好な結果であった.相対的用量強度は6コース時点でL-OHP 89.2%,Xeloda 91.0%で良好であった.またその効果はCR/PR/NC/PD割合がそれぞれ10%/56.7%/16.7%/3.3%で奏効率66.7%,病勢制御率96.7%と満足できる結果であった.[結語]今後も増加するであろう外来での抗癌剤治療では,自宅での管理がより一層重要となる.チームでの取り組みは今後更に必要になると考えられる.(著者抄録)

Laparoscopic gastrointestinal surgery with lymphadenectomy is rarely performed for multiple gastrointestinal cancers. We report four patients undergoing laparoscopic surgery for synchronous cancer of the stomach and colon. Resection of each organ with lymphadenectomy was performed by each specialist and the region of the lymphadenectomy was determined according to the lesion of cancer and its depth. The selection of gastric anastomosis, whether intracorporeal or extracorporeal, depended on the resecting areas of the large bowel to allow a small incision. All four cases were male with the median age of 69 (range 59-77) years. The median number of trocars used were 6 (range 5-8) and median length of incision was 4.5cm (range 4-4.5cm). The median operative time and blood loss were 495.5 minutes (range 390-605) and 88g (range 36-245), respectively. In all four cases, laparoscopic surgery with a lymphadenectomy on each region was successfully accomplished according to the respective progression stage. Anastomosis was completed with a small incision by using techniques and devices to provide a variation of anastomosis methods and incision positions. Laparoscopic surgery with lymphadenectomy was also undertaken for a patient with gastric remnant cancer and colorectal cancer. The median length of the postoperative hospital stay was 14.5 days (range 12-29). No complications were observed after the surgery. There was no case of recurrence during a median follow-up of 84.3 months (range 54.9-111.5). Laparoscopic surgery was feasible for patients with double cancer of the stomach and colon.

Stomal prolapse is one of the common complications in transverse colostomy and can be managed conservatively in most cases; however, laparotomy and reconstruction of the stoma may sometimes be required, especially in case of irreducible colostomy prolapse. We have reported a simple local repair with reconstruction of the loop colostomy. We herein report a new more simple technique to avoid laparotomy and allow excision of the irreducible colostomy prolapse and complete closure of the distal limb of loop colostomy when no decompression is required in the distal limb of the stoma. In this procedure, the number of stapler and the time with blood loss for the operation can be saved.

2009年9月に大腸癌に対するda Vinci Surgical Systemを用いたロボット手術を導入し,これまでに20例を経験した.今回は,そのなかで下部直腸癌3例に対して内括約筋切除術(ISR)を施行したので,その手技と手術成績を報告する.術前診断でcT1の2例と,経肛門的腫瘍切除(MITAS)術後の1例であり,いずれも側方郭清の必要のない症例を選択した.平均手術時間は512分,出血量は113gで,術後平均在院日数は9日であった.1例に骨盤内膿瘍を認めたが,保存的治療で軽快した.病理組織検査で,郭清リンパ節は平均17個であり,Surgical Marginも全例negativeであった.Learning curveによる手術時間の短縮とさらなる症例の蓄積によってfeasibilityと安全性を示す必要があると考えられた.(著者抄録)

Solitary fibrous tumors (SFTs) develop most commonly in the pleura, although they have occasionally been reported to arise in the pelvic cavity. We report a case of an SFT presenting as a painless nodule in the pelvis of a 56-year-old woman. Histologically, the tumor was composed of spindle-shaped cells arranged without pattern, with short and narrow fascicles and interspersed bundles of thick collagen, and numerous blood vessels with a focally hemangiopericytoma-like appearance. Immunohistochemically, the tumor cells strongly expressed vimentin, CD34, and bcl-2. The tumor was excised via a trans-sacral approach, without preoperative transcatheter embolization, and the patient remains well more than 2 years after her operation. To our knowledge, this is the first case of an SFT in the pelvis, which was excised completely via a trans-sacral approach.

[はじめに]直腸脱術後の直腸肛門機能に関する報告はほとんどない。本論文では直腸脱に対する腹腔鏡下直腸固定術前後の直腸肛門機能の変化を検討した。[対象および方法]1996〜2006年までに腹腔鏡下直腸固定術(Well's法)を施行した12例を対象とし、直腸肛門内圧測定はマイクロトランスデューサー法にて施行した。術後の臨床的排便機能評価にはWexner's scoreおよび患者アンケートを用いた。[結果]腹腔鏡下直腸固定術後には、肛門管最大静止圧が有意に(P=0.048)上昇した。その他の値は有意な変化を示さなかった。術後のWexner's scoreは有意に(P=0.037)改善し、患者の満足度も高かった。[結語]腹腔鏡下直腸固定術後には、肛門管最大静止圧が有意に上昇し、臨床的な排便機能にも改善がみられた。(著者抄録)