Curriculum Vitaes
Profile Information
- Affiliation
- Fujita Health University
- Degree
- 医学博士(慶應義塾大学)
- Other name(s) (e.g. nickname)
- https://bantane.fujita-hu.ac.jp/department/obstericians.html
- J-GLOBAL ID
- 200901012107446377
- researchmap Member ID
- 5000096026
日本産科婦人科学会 産婦人科専門医
日本産科婦人科学会 産婦人科指導医
日本生殖医学会認定 生殖医療専門医
日本生殖医学会認定 生殖医療指導医
日本婦人科腫瘍学会 婦人科腫瘍専門医
日本婦人科腫瘍学会 婦人科腫瘍指導医
日本がん治療認定医機構 がん治療認定医
日本がん治療認定医機構 暫定教育医
Research Interests
14Research Areas
1Research History
15-
Apr, 2023 - Present
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Apr, 2020 - Mar, 2023
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Mar, 2019 - Mar, 2023
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Oct, 2018 - Mar, 2023
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Apr, 2008 - Mar, 2023
Education
2-
1995 - 1999
Committee Memberships
5-
May, 2012
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2011
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2011
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2009
Awards
5-
2013
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2009
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2008
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2008
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2004
Major Papers
55-
Nature Communications, 5(448) 1-9, Jul 22, 2014 Peer-reviewed
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Proc. Natl. Acad. Sci. USA （PNAS）, 108(49) 19587-92, Dec 6, 2011 Peer-reviewed
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Proc. Natl. Acad. Sci. USA （PNAS）, 106(9) 3095-100, Mar 3, 2009 Peer-reviewed
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Proc. Natl. Acad. Sci. USA （PNAS）, 104(10) 3799-804, Mar 6, 2007 Peer-reviewed
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Science, 295(5552) 124-7, Jan 4, 2002 Peer-reviewed
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Nature cell biology, 4(1) 73-8, Jan, 2002 Peer-reviewedThe Ras-related small GTPase RalA is involved in controlling actin cytoskeletal remodelling and vesicle transport in mammalian cells. We identified the mammalian homologue of Sec5, a subunit of the exocyst complex determining yeast cell polarity, as a specific binding partner for GTP-ligated RalA. Inhibition of RalA binding to Sec5 prevents filopod production by tumor necrosis factor-alpha (TNF-alpha) and interleukin-1 (IL-1) and by activated forms of RalA and Cdc42, signalling intermediates downstream of these inflammatory cytokines. We propose that the RalA-exocyst complex interaction integrates the secretory and cytoskeletal pathways.
Misc.
70-
日本産科婦人科学会雑誌, 64(2) 718-718, Feb, 2012 Peer-reviewed
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GLYCOBIOLOGY, 21(11) 1467-1467, Nov, 2011 Peer-reviewed
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PLACENTA, 32(9) A167-A167, Sep, 2011 Peer-reviewed
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PLACENTA, 32(9) A99-A99, Sep, 2011 Peer-reviewed
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関東連合産科婦人科学会誌, 48(3) 367-367, Aug, 2011 Peer-reviewed
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日本産婦人科感染症研究会学術講演会記録集, (29) 95-95, Jun, 2011
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PLACENTA, 31(9) A154-A154, Sep, 2010 Peer-reviewed
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JOURNAL OF UROLOGY, 183(5) 2102-2102, May, 2010 Peer-reviewed
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日本産科婦人科学会関東連合地方部会誌, 46(3) 264-264, Aug, 2009 Peer-reviewed
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PLACENTA, 28(10) A7-A7, Oct, 2007 Peer-reviewed
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PLACENTA, 28(8-9) A77-A77, Aug, 2007 Peer-reviewed
Books and Other Publications
12Presentations
6Works
4-
2014 Othershttp://www.natureasia.com/ja-jp/ncomms/abstracts/55462
Major Research Projects
22-
基盤研究（C）, Apr, 2023 - Mar, 2026
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基盤研究（B）, Apr, 2019 - Mar, 2023
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AMED橋渡し研究シーズＡ, 2019 - 2020
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挑戦的萌芽研究, Apr, 2015 - Mar, 2018
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基盤研究（B）, Apr, 2015 - Mar, 2018
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基盤研究（B）, Apr, 2012 - Mar, 2015
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挑戦的萌芽研究, Apr, 2012 - Mar, 2015
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基盤研究（B）, Apr, 2011 - Mar, 2014
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知財活用促進ハイウェイ, 科学技術振興機構(JST), Apr, 2012 - Mar, 2013
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Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Apr, 2009 - Mar, 2012
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Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Apr, 2008 - Mar, 2011
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上原記念生命科学財団
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高松宮妃癌研究助成基金
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創薬支援ネットワーク（日本版NIH）→AMED（日本医療研究開発機構）