研究者業績

太田好次

オオタヨシジ (Yoshiji Ohta)

基本情報

所属: 藤田保健衛生大学医学部一般教育化学教授

学位: 博士(医学)(藤田保健衛生大学)
修士(薬学)(岐阜薬科大学)

J-GLOBAL ID: 200901088910182423
researchmap会員ID: 1000102491

研究分野

2

経歴

8

1993年 - 1999年

藤田保健衛生大学医学部助教授
1993年 - 1999年

藤田医科大学
1984年 - 1993年

藤田学園保健衛生大学医学部講師
1984年 - 1993年

Fujita-Gakuen Health University School of Medicine, Assitant Professor
1973年 - 1984年

名古屋保健衛生大学医学部助手

もっとみる

学歴

4

委員歴

5

MISC

176

Modulating role of endogenous reduced glutathione in t-butyl hydoroperoxide-induced cell injury in isolated rat hepatocytes.（共著）

Free Radical Biology and Medicine 23(3), 453-462 1997年
Comparative study of oral and parenteral administration of Sho-saiko-to (Xiao-Chaihu-Tang) extract on progression of D-galactosamine-induced liver injury in rats.（共著）

American Journal of Chinese Medicine 25(3-4), 333-342 1997年
Preventive action of vitamin E-containing liposomes on cataractogenesis in young adult rats fed a 25% galactose diet.（共著）

Journal of Otular Pharmacology and Therapeutics 13(6), 537-550 1997年
Relationship between changes of active oxygen metabolism and blood flow and formation, progression, and recovery of lesions in gastric mucosa of rats with a single treatment of compound 48/80, a mast cell degranulator.（共著）

Digestive Diseases and Sciences 42(6), 1221-1232 1997年
Preventive effect of Oren-gedoku-to (Huanglian-Jie-Du-Tang) extract on progression of carbon tetrachloride induced acute liver injury in rats.（共著）

American Journal of Chinese Medicine 25(1), 57-68 1997年
Attenuation of disrupted hepatic active oxygen metabolism with the recovery of acute liver injury in rats intoxicated with carbon tetrachloride.（共著）

Research Communications in Molecular Pathology and Pharmcology 95(2), 191-207 1997年
Glycine facilitates γ-glutamylcysteinylethyl ester-mediated increase in liver glutathione level. "jointly worked"

European Journal of Pharmacology 333(2-3), 289-292 1997年
Role of gastric mucosal constitutive and inducible nitric oxide synthases in the development of stress-induced gastric mucosal lesions in rats. "jointly worked"

Biochemical and Biophysical Research Communications 236(2), 275-279 1997年
Involvement of the xanthine-xanthine oxidase system and neutrophils in the development of acute gastric mucosa1 lesions gastric mucosal lesions in rats with water immersion restraint stress. "jointly worked"

Digestion 58(4), 340-351 1997年
Changes in serum L-tryptophan levels following the development and recovery of acute puromycin aminonucleoside nephrosis in rats. "jointly worked"

Amino Acids 12(3-4), 353-361 1997年
Modulating role of endogenous reduced glutathione in t-butyl hydoroperoxide-induced cell injury in isolated rat hepatocytes. "jointly worked"

Free Radical Biology and Medicine 23(3), 453-462 1997年
Comparative study of oral and parenteral administration of Sho-saiko-to (Xiao-Chaihu-Tang) extract on progression of D-galactosamine-induced liver injury in rats. "jointly worked"

American Journal of Chinese Medicine 25(3-4), 333-342 1997年
Preventive action of vitamin E-containing liposomes on cataractogenesis in young adult rats fed a 25% galactose diet. "jointly worked"

Journal of Otular Pharmacology and Therapeutics 13(6), 537-550 1997年
Relationship between changes of active oxygen metabolism and blood flow and formation, progression, and recovery of lesions in gastric mucosa of rats with a single treatment of compound 48/80, a mast cell degranulator. "jointly worked"

Digestive Diseases and Sciences 42(6), 1221-1232 1997年
Preventive effect of Oren-gedoku-to (Huanglian-Jie-Du-Tang) extract on progression of carbon tetrachloride induced acute liver injury in rats. "jointly worked"

American Journal of Chinese Medicine 25(1), 57-68 1997年
Attenuation of disrupted hepatic active oxygen metabolism with the recovery of acute liver injury in rats intoxicated with carbon tetrachloride. "jointly worked"

Research Communications in Molecular Pathology and Pharmcology 95(2), 191-207 1997年
Response of endogenous reduced glutathione through hepatic glutathione redox cycle to enhancement of hepatic lipid peroxidation with the development of acute liver injury in mice intoxicated with carbon tetrachloride.（共著）

Research Communications in Molecular Pathology and Pharmacology 93(2), 198-218 1996年
Conversion of γ-glutamylcysteinylethyl ester to glutathione in rat hepatocytes.（共著）

Biochimica Biophysica Acta 1313(1), 47-53 1996年
Role of catalase in retinal antioxidant defence system: Its comparative study among rabbits, guniea pig, and rats.（共著）

Ophthalmic Research 28(6), 336-342 1996年
Role of the prosthetic groups of NADPE-cytochrome P-450 reductase in 3-hydroxyanthranilamide-catalyzed, NADPH-dependent superoxlde anion production.（共著）

Redox Report 2(5), 339-344 1996年
Relationship between the level of serum L-tryptophan and its hepatic uptake and metabolism in rats with carbon tetrachloride-induced liver cirrhosis.（共著）

Amino Acids 10(4), 369-378 1996年
Disruption of gastric mucosal antioxidant defense system and its relation to the development of gastric mucosal 1esions in rats with repeated treatment of compound 48/80, a mast cell degranulator.（共著）

Pathophysiology 3(3) 187-195 1996年
Anticataract action of vitamin E: Its estimation uisng in vitro steroid cataract model.（共著）

Ophthalmic Research 28(Supp1 2), 16-25 1996年
Involvement of oxidative stress in D-xylose-induced cataractogenesis in cultured rat lenses.（共著）

Current Eye Research 15(1), 1-7 1996年
Response of endogenous reduced glutathione through hepatic glutathione redox cycle to enhancement of hepatic lipid peroxidation with the development of acute liver injury in mice intoxicated with carbon tetrachloride. "jointly worked"

Research Communications in Molecular Pathology and Pharmacology 93(2), 198-218 1996年
Conversion of γ-glutamylcysteinylethyl ester to glutathione in rat hepatocytes. "jointly worked"

Biochimica Biophysica Acta 1313(1), 47-53 1996年
Role of catalase in retinal antioxidant defence system: Its comparative study among rabbits, guniea pig, and rats. "jointly worked"

Ophthalmic Research 28(6), 336-342 1996年
Role of the prosthetic groups of NADPE-cytochrome P-450 reductase in 3-hydroxyanthranilamide-catalyzed, NADPH-dependent superoxlde anion production. "jointly worked"

Redox Report 2(5), 339-344 1996年
Relationship between the level of serum L-tryptophan and its hepatic uptake and metabolism in rats with carbon tetrachloride-induced liver cirrhosiAmino Acidss. "jointly worked"

Amino Acids 10(4), 369-378 1996年
Disruption of gastric mucosal antioxidant defense system and its relation to the development of gastric mucosal 1esions in rats with repeated treatment of compound 48/80, a mast cell degranulator. "jointly worked"

Pathophysiology 3(3), 187-195 1996年
Anticataract action of vitamin E: Its estimation uisng in vitro steroid cataract model. "jointly worked"

Ophthalmic Research 28(Supp1 2), 16-25 1996年
Involvement of oxidative stress in D-xylose-induced cataractogenesis in cultured rat lenses. "jointly worked"

Current Eye Research 15(1), 1-7 1996年
Preventive effect of Dai-Saiko-to (Da-Chai-Hu-Tang) extract on disrupted hepatic active oxygen metabolism in rats with carbon tetrachloride-induced liver injury.（共著）

American Journal of Chinese Medicine 23(1), 53-64 1995年
Preventive effect of Dai-Saiko-to (Da-Chai-Hu-Tang) extract on disrupted hepatic active oxygen metabolism in rats with carbon tetrachloride-induced liver injury. "jointly worked"

American Journal of Chinese Medicine 23(1), 53-64 1995年
Facilitating effect of albumin on L-tryptophan transport into isolated rat hepatocytes.（共著）

Journal of Clinical Biochemistry and Nutrition 16(1), 15-26 1994年
Facilitating effect of albumin on L-tryptophan transport into isolated rat hepatocytes. "jointly worked"

Journal of Clinical Biochemistry and Nutrition 16(1), 15-26 1994年
Changes in level of galalctose, N-acetylneuraminic acid-galactose, and N-acetylneur aminic acid in the serum and tissues of rats with experimental diabetes or liver injury.（共著）

Medical Science Research 21, 637-638 1993年
Mechanism of immunological cell injury in isolated rat hepatocytes with anti-rat liver plasma membrane antiserum treatment.（共著）

International Hepatology Communications 1(3), 278-282 1993年
Preventive effect of γ-glutamylcysteinylethyl ester on immunologicalcell injury in isolated rat hepatocytes with anti-rat liver plasma membrane antiserum treatment.（共著）

Research Communications in Chemical Pathology and Pharmacology 82(1), 49-64 1993年
Effect of albumin on the disappearance of L-tryptophan from the perfusate into isolated perfused rat livers.（共著）

e into isolated perfused rat livers. Journal of Clinical Biochemistry and Nutrition 15(3), 185-194 1993年
Inhibitory effets of "group A saponin" and "group B saponin" fraction from soybean hypocotyls on radical-induced lipid peroxidation in mouse liver microsomes.（共著）

Journal of Clinical Biochemistry and Nutrition 15(3), 175-184 1993年
Changes in level of galalctose, N-acetylneuraminic acid-galactose, and N-acetylneur aminic acid in the serum and tissues of rats with experimental diabetes or liver injury. "jointly worked"

Medical Science Research 21, 637-638 1993年
Mechanism of immunological cell injury in isolated rat hepatocytes with anti-rat liver plasma membrane antiserum treatment. "jointly worked"

International Hepatology Communications 1(3), 278-282 1993年
Preventive effect of γ-glutamylcysteinylethyl ester on immunologicalcell injury in isolated rat hepatocytes with anti-rat liver plasma membrane antiserum treatment. "jointly worked"

Research Communications in Chemical Pathology and Pharmacology 82(1), 49-64 1993年
Effect of albumin on the disappearance of L-tryptophan from the perfusate into isolated perfused rat livers. "jointly worked"

Journal of Clinical Biochemistry and Nutrition 15(3), 185-194 1993年
Inhibitory effets of "group A saponin" and "group B saponin" fraction from soybean hypocotyls on radical-induced lipid peroxidation in mouse liver microsomes. "jointly worked"

Journal of Clinical Biochemistry and Nutrition 15(3), 175-184 1993年
Refolding of denatured subtilisins with the aid of an active center mutant pro-subtilisin and synthetic pro-peptide; Sequence-specific effects on refolding by an intermolecular chaperon.（共著）

Biochemistry (Life Science Advance) 11(1), 35-47 1992年
Refolding of denatured subtilisins with the aid of an active center mutant pro-subtilisin and synthetic pro-peptide; Sequence-specific effects on refolding by an intermolecular chaperon. "jointly worked"

Biochemistry (Life Science Advance) 11(1), 35-47 1992年
Characterization of the tryptophan transport system in the liver of growing rats.（共著）

Life Science 49(7), 527-534 1991年
Pro-peptide as an intermolecular chaperone: renaturation of denatured subtilisin E with a synthetic pro-peptide.（共著）

Molecular Microbiology 5(6), 1507-1510 1991年

所属学協会

15

もっとみる

Works(作品等)

8

急性胃粘膜障害に対するプラウノトールの治療効果に関する研究

2001年 - 2002年
Therapeutic effect of plaunotol on acute gastric mucosal lesions

2001年 - 2002年
柴胡桂枝湯エキス剤の肝・胆道疾患に対する抑制効果

1998年 - 1999年
Preventive effect of Saiko-Keishi-to extract on hepatobilirary injury

1998年 - 1999年
テプレノンの胃粘液分泌機序、好中球およびNOとの関連からの検討

1996年

もっとみる

共同研究・競争的資金等の研究課題

6

L-トリプトファンの肝細胞への輸送とその調節

1985年
Transport of L-tryptophan into hepatocytes and its regulation

1985年
白内障の成因と抗白内障薬の開発

1980年
Causative factors of cataract and development of anti-cataract drug

1980年
各種疾患とフリーラジカルとの関連性

1977年

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