Curriculum Vitaes

yoshida shunji

  (吉田 俊治)

Profile Information

Affiliation
School of Medicine Faculty of Medicine, Fujita Health University
Degree
医学博士(慶應義塾大学)

J-GLOBAL ID
200901069524958170
researchmap Member ID
1000102526

Misc.

 57
  • Ayako Kondo, Kazuo Takahashi, Tomohiro Mizuno, Akihiro Kato, Daisuke Hirano, Naoki Yamamoto, Hiroki Hayashi, Shigehisa Koide, Hiroshi Takahashi, Midori Hasegawa, Yoshiyuki Hiki, Shunji Yoshida, Keiji Miura, Yukio Yuzawa
    PLoS One, 11(10), Oct, 2016  
    Anti-endothelial cell antibodies (AECA) are frequently detected in patients with systemic lupus erythematosus (SLE), but their pathological role remains unclear. We recently developed a solubilized cell surface protein capture enzyme-linked immunosorbent assay (CSPELISA) to detect antibodies against membrane proteins involved in autoimmune reactions. In this study, sera from 51 patients with biopsy-proven lupus nephritis (LN), 25 with SLE without renal involvement (non-LN SLE), 42 disease control (DC) subjects, and 80 healthy control (HC) subjects were tested for IgG-and IgA-AECA for human umbilical vein endothelial cells (HUVEC) and human glomerular EC (HGEC) by using CSP-ELISA. IgG-and IgA-AECA titers were significantly higher in LN and non-LN SLE patients than in the DC or HC (P < 0.001) groups. IgG-and IgA-AECA titers for HUVEC corresponded well with those for HGEC. The IgA-AECA level correlated with the SLE disease activity index and with histological evidence of active lesions (cellular proliferations, hyaline thrombi and wire loops, leukocytic infiltration, and fibrinoid necrosis) in LN patients (P < 0.001). The sensitivity of IgA-AECA as a diagnostic test for histological evidence of active lesions in LN patients was 0.92, with a specificity of 0.70. The significant correlation of IgA-AECA with glomerular hypercellularity indicates that IgA-AECA are associated with endothelial damage in LN.
  • Joji Inamasu, Kiyohito Ishikawa, Motoki Oheda, Shunsuke Nakae, Yuichi Hirose, Shunji Yoshida
    JOURNAL OF INFECTION AND CHEMOTHERAPY, 22(3) 184-186, Mar, 2016  Peer-reviewed
    Infection by bacteria carrying New Delhi metallo-beta-lactamase 1 (NDM-1) is becoming a global health problem. We report a case of meningitis caused by NDM-1-producing Klebsiella pneumoniae, for which intrathecal administration of colistin was curative. A previously healthy 38-year-old Japanese man, who lived in Hyderabad, India, suddenly collapsed and was brought to a local hospital. He was diagnosed with subarachnoid hemorrhage and underwent emergency surgery which included partial skull removal. Approximately 1 month after surgery, he was repatriated to Japan and was admitted to our institution with information that he had been treated for multi-drug resistant Acinetobacter infection with colistin. A week after admission, he developed aspiration pneumonia due to NDM-1-producing K. pneumoniae, which was successfully treated by intravenous (IV) administration of colistin. Subsequently, he underwent a surgical procedure to repair his skull defect. He developed high-grade fever and altered mental status on postoperative day 2. NDM-1-producing K. pneumoniae was identified in the cerebrospinal fluid, establishing the diagnosis of meningitis. Although IV colistin was only partially effective, intrathecal colistin (10 mg daily by lumbar puncture for 14 days) successfully eradicated the meningitis. Because of economic globalization, NDM-1-producing bacteria may be brought to Japan by those who are repatriated after sustaining critical illnesses and being treated in foreign countries. This report may provide useful information on the treatment of central nervous system infection by NDM-1-producing bacteria. (C) 2015, Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.
  • 吉田俊治
    呼吸と循環, 64(5) 30-31, 2016  
  • 吉田俊治
    微研ジャーナル友, 39(4) 3-7, 2016  
  • 加藤賢一, 平野大介, 橋本貴子, 吉田俊治
    腎と透析, 81(3) 333-337, 2016  

Books and Other Publications

 8

Presentations

 87

作成した教科書、教材、参考書

 1
  • 件名(英語)
    内科学書 vol.2
    終了年月日(英語)
    2009
    概要(英語)
    高安動脈炎/p195-197を執筆

その他教育活動上特記すべき事項

 11
  • 件名(英語)
    医学教育ワークショップ
    終了年月日(英語)
    2009/05/18
    概要(英語)
    「PBLテュータ・トレーニング」に参加
  • 件名(英語)
    第23回医学教育ワークショップ
    終了年月日(英語)
    2008/05/17
    概要(英語)
    「CBT試験問題作成」に参加
  • 件名(英語)
    第28回医学教育ワークショップ
    終了年月日(英語)
    2009/05/16
    概要(英語)
    「CBT試験問題作成」に参加
  • 件名(英語)
    第30回医学教育ワークショップ
    終了年月日(英語)
    2009/08/29
    概要(英語)
    「計算問題、多肢選択問題、臨床長文問題」に参加
  • 件名(英語)
    第32回医学教育ワークショップ
    終了年月日(英語)
    2009/12/20
    概要(英語)
    「臨床教育の改善」に参加
  • 件名(英語)
    第33回医学教育ワークショップ
    終了年月日(英語)
    2010/05/15
    概要(英語)
    「CBT試験問題作成」に参加
  • 件名(英語)
    第38回医学教育ワークショップ
    終了年月日(英語)
    2011/04/30
    概要(英語)
    「CBT試験問題作成」に参加
  • 件名(英語)
    教務副委員長
    開始年月日(英語)
    2009/04/01
    概要(英語)
    2009/04~2012/3/31
  • 件名(英語)
    学生指導委員長
    開始年月日(英語)
    2012/04/01
    概要(英語)
    2012/04~2013/3/31
  • 件名(英語)
    第46回医学教育ワークショップ
    終了年月日(英語)
    2013/04/27
    概要(英語)
    CBT試験問題作成・ブラッシュアップワークショップに参加
  • 件名(英語)
    第48回医学教育ワークショップ
    終了年月日(英語)
    2013/08/18
    概要(英語)
    1卒業時、および臨床実習終了時アウトカムの設定に参加