研究者業績
基本情報
- 所属
- 藤田医科大学 総合消化器外科 客員講師
- 学位
- 医学博士(新潟大学大学院)
- 研究者番号
- 30757505
- J-GLOBAL ID
- 201801017968110630
- researchmap会員ID
- B000302641
2007年(平成19年)4月より新潟大学医歯学総合病院消化器・一般外科勤務
2015年(平成27年)6月より新潟大学医歯学総合病院光学医療診療部助教
2018年(平成30年)10月より藤田医科大学総合消化器外科講師(国内留学)
2015年(平成27年)6月より新潟大学医歯学総合病院光学医療診療部助教
2018年(平成30年)10月より藤田医科大学総合消化器外科講師(国内留学)
研究分野
1論文
243-
Gan to kagaku ryoho. Cancer & chemotherapy 51(13) 1520-1522 2024年12月A 73-year-old man with a history of perianal abscess and anal fistula for approximately 40 years visited our outpatient clinic because of anal pain. An anal tumor was found at the initial visit. Colonoscopy also revealed a circumferential rectosigmoid tumor located 15 cm from the anal verge. The initial diagnosis was double primary cancer: Stage ⅡB anal fistula cancer(T3N0M0)and cStage Ⅱa rectosigmoid cancer(cT3N0M0). He underwent abdominoperineal resection with curative intent. Histopathological examination revealed that both tumors were moderately differentiated adenocarcinoma. In addition, genetic testing revealed that both tumors were KRAS G12V mutated, BRAFV600E wild, and microsatellite stable. The final diagnosis was metastatic carcinoma of anal fistula caused by implantation from rectal cancer.
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International journal of clinical oncology 29(6) 790-800 2024年6月BACKGROUND: Initial chemotherapy (Initial-C) followed by surgery is a promising treatment strategy for peritoneal lavage cytology-positive gastric cancer (CY1 GC) with no other noncurative factors. The aim of this study was to investigate the survival advantage of Initial-C compared to initial surgery (Initial-S) for this disease according to the macroscopic type, which was associated with prognosis and the efficacy of chemotherapy in GC. METHODS: One hundred eighty-nine patients who were diagnosed with CY1 GC with no other noncurative factors at four institutions from January 2007 to December 2018 were enrolled. The patients were divided into a macroscopic type 4 group (N = 48) and a non-type 4 group (N = 141). The influence of initial treatment on overall survival (OS) in each group was evaluated. RESULTS: In the type 4 group, the 5-year OS rates of Initial-C (N = 35) and Initial-S (N = 13) were 11.6% and 0%, respectively (P = 0.801). The multivariate analysis could not show the survival advantage of Initial-C. In the non-type 4 group, the 5-year OS rates of Initial-C (N = 41) and Initial-S (N = 100) were 48.4% and 29.0%, respectively (P = 0.020). The multivariate analysis revealed that Initial-C was independently associated with prolonged OS (hazard ratio, 0.591; 95% confidence interval, 0.375-0.933: P = 0.023). CONCLUSIONS: Initial-C improves the prognosis of non-type 4 CY1 GC with no other noncurative factors. On the other hand, further development of effective chemotherapeutic regimens and innovative treatment strategies are required for type 4 CY1 GC.
MISC
367-
Journal of the anus, rectum and colon 4(1) 14-24 2020年The number of patients undergoing robotic surgery for rectal cancer has rapidly increased in Japan, since the government approved the procedure for national insurance coverage in April 2018. Robotic surgery has the potential to overcome some limitations of laparoscopic surgery, especially in the narrow pelvis, providing a three-dimensional view, articulated instruments, and a stable camera platform. Although meta-analyses and randomized controlled trials have failed to demonstrate the superiority of robotic surgery over laparoscopic surgery with respect to the short-term clinical outcomes, the published findings suggest that robotic surgery may be potentially beneficial for patients who are obese, male, or patients undergoing sphincter-preserving surgery for rectal cancer. The safety and feasibility of robotic surgery for lateral lymph node dissection, the standard procedure for locally advanced lower rectal cancer in Japan, have been demonstrated in some retrospective studies. However, additional prospective, randomized trials are required to determine the actual benefits of robotic surgery to ameliorate the urogenital and oncological outcomes. The cost of this approach is a long-standing principal concern. A literature search showed that the cost of robotic surgery for rectal cancer was 1.3-2.5 times higher per patient than that for the laparoscopic approach. We herein describe our surgical technique using a da Vinci Surgical System (S/Si/Xi) with 10 years of experience in performing robotic surgery. We also review current evidence regarding short-term clinical and long-term oncological outcomes, lateral lymph node dissection, and the cost of the procedure.
共同研究・競争的資金等の研究課題
10-
日本学術振興会 科学研究費助成事業 2023年4月 - 2026年3月
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日本学術振興会 科学研究費助成事業 2022年6月 - 2025年3月
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日本学術振興会 科学研究費助成事業 2022年4月 - 2025年3月
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日本学術振興会 科学研究費助成事業 2022年4月 - 2025年3月
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日本学術振興会 科学研究費助成事業 2022年4月 - 2025年3月