基本情報
- 所属
- 日本獣医生命科学大学 獣医学部 獣医学科 獣医外科学研究室 准教授
- 学位
- 博士(医学)(京都大学)
- J-GLOBAL ID
- 200901041793340954
- researchmap会員ID
- 5000081047
研究キーワード
10研究分野
1論文
105-
Veterinary and comparative orthopaedics and traumatology : V.C.O.T 2024年8月29日OBJECTIVE: The aim of this study was to identify risk factors for refracture after radial union in small-breed dogs. STUDY DESIGN: In our retrospective study, medical records of radial-ulnar fracture cases in small dogs treated with plates and screws were reviewed. General information and postoperative course (days until confirmed radial fracture healing, with or without ulnar union, time to final follow-up, with or without plate removal and refracture) were recorded. The fracture line location, screw positions, radial thickness and width, and pixel values throughout the postoperative periods were obtained from the radiographs. The affected limbs were classified into non-plate removal (P) and plate removal (R) groups. RESULTS: Refracture occurred in 5 of the 141 limbs at the most distal screw in the P group and 5 of the 40 limbs at the same site as the initial fracture in the R group. Multivariate analysis indicated that refracture was linked to the amount of relative change with growth in the position of the most distal screw in the P group, with pixel value and radial thickness ratios at the same site as the initial fracture in the R group. CONCLUSION: Reducing the screw diameter relative to the radial width to the appropriate extent may be considered in cases where the screw positioned at the most distal end of the radius is expected to be relatively proximal as the distal radius grows; not removing the plate may be considered in cases with a decreased radial thickness or bone mineral density beneath the plate during plate removal.
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Veterinary and comparative orthopaedics and traumatology : V.C.O.T 2024年3月6日OBJECTIVE: The aim of this study was to evaluate the stress changes in the radii beneath the locking plates (LP) of dogs implanted with LP using finite element analysis (FEA). STUDY DESIGN: The study included radii harvested from eight dogs. After computed tomography (CT) scans of the forelimb, the articular surface of the radius was fixed using resin. Material tests were conducted to identify the yield and fracture points and for verification with FEA. The CT data of the radius were imported into FEA software. The radii were classified into three groups based on the placement of the LP (nonplate placement, intact group; 1 mm above the radial surface, LP + 1 mm group; 3 mm above the radial surface, LP + 3 mm group). Equivalent, maximum, and minimum principal stresses and minimum principal strain were measured after FEA at the radial diaphysis beneath the plate. RESULTS: In shell elements, the LP + 1 mm and LP + 3 mm groups showed a significantly lower maximum principal stress compared with the intact group. In solid elements, the LP + 1 mm and LP + 3 mm groups showed a significantly higher equivalent stress and a significantly lower maximum principal stress compared with the intact group. CONCLUSION: When an axial load is applied to the radius, LP placement reduces the tension stress on the cortical bone of the radius beneath the plate, possibly related to implant-induced osteoporosis and bone formation in the cortical bone beneath the plate.
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Journal of Veterinary Medical Science 2024年
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American journal of veterinary research 1-9 2023年5月29日OBJECTIVE: To determine the signalment and musculoskeletal morphology of small-breed dogs affected by medial patellar luxation (MPL) grade IV based on the age of the CT scan. ANIMALS: 40 small-breed dogs (54 limbs) with MPL grade IV. PROCEDURES: Dogs that had undergone corrective surgery for MPL grade IV and had performed CT of the hind limb before surgery were included. Signalment (age, body weight, sex, laterality, and breed) and concomitant cranial cruciate ligament rupture (CrCLR) were recorded. Femoral inclination angle, anatomical lateral distal femoral angle (aLDFA), femoral torsion angle, quadriceps muscle length to femoral length ratio (QML/FL), and patellar ligament length to patellar length were obtained by CT images. The dogs were categorized into 2 groups based on their age at the time of the CT scan, the skeletally immature group and the skeletally matured group. Signalment and group were included in the multiple regression analysis to determine the factors associated with each measurement parameter. A logistic regression analysis was conducted to determine the risk of CrCL concomitant with age. RESULTS: The multiple regression model demonstrated that the group was associated with the value of aLDFA and QML/FL. aLDFA was higher, and QML/FL was lower in group SI than in group SM. CrCLR was present in 5/54 limbs (9.2%), with a mean age of 70.8 months and it was associated with increasing age. CLINICAL RELEVANCE: In Singleton's classification, dogs classified as grade IV can be categorized into 2 groups based on musculoskeletal morphology and pathophysiology: the skeletally immature and skeletally matured types.
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Veterinary Surgery 2023年3月7日
MISC
411-
バイオエンジニアリング学術講演会・セミナー講演論文集 2004 81-82 2005年
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生体内環境設計のためのCA法を用いたES細胞-軟骨再生シミュレーションモデル(S02-1 生体組織のマルチスコープメカニクス(1).モデリングとメカニクス,S02 生体組織のマルチスコープメカニクス)年次大会講演論文集 2004 1-2 2004年This paper describes a tissue-regenerating model using a cellular automaton for Bio-environment designing. The model consists of identical cells which mechanically connect with each other. The mechanical relation state of each cell is calculated using FEM. The local rules are "death" which is induced by apoptosis, "birth" and "transition". In this model, each cell means not "cell" but tissue which have the information of an adapted function for the mechanical environment. The morphology and the function constructed by this model were formed autonomically through the way of selection on the mechanical environment. Results of in-vivo testing using ES cell transplantation were used as reference of this model.
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年次大会講演論文集 2004 25-26 2004年
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日本臨床バイオメカニクス学会誌 = Proceedings of ... Annual Meeting of Japanese Society for Clinical Biomechanics and Related Research 24 45-51 2003年11月1日初期細胞接着を向上させる目的でフィブロインスポンジを硫酸化処理し,表面改質を狙い,従来のフィブロインスポンジとの比較検討を行った.硫酸化フィブロインスポンジ内でも,軟骨細胞はその分化能力を失うことなく増殖可能であったが,硫酸化処理による明らかな追加効果は得られず,得られた硝子軟骨様組織は従来のフィブロインと同様に部分的であった.著者等は,フィブロインスポンジ内において,軟骨細胞は分化能力を失うことなく増殖可能である理由を,培養初期には,細胞がフィブロイン表面の一部に接着した状態で培養されることにより細胞数が増加し,その後,細胞周囲に細胞外基質が産生されるに伴い培養条件が三次元の状態に移行し,良好な軟骨様組織を構築したのではないかと考察した
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日本獣医学会学術集会講演要旨集 136回 204-204 2003年9月
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The Journal of Veterinary Medical Science 65(1) 103-107 2003年1月
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日本臨床バイオメカニクス学会誌 = Proceedings of ... Annual Meeting of Japanese Society for Clinical Biomechanics and Related Research 23 13-18 2002年11月1日絹フィブロインを用いて平均pore size 80μmのハイドロゲルスポンジを作製し,ウサギの軟骨細胞を播種,培養して組織学的評価を行った.培養3日目より細胞外基質の産生を認め,7日目には部分的にフィブロインスポンジのpore内に細胞外基質に周囲を取り囲まれた細胞集団を認めた.14日目にはフィブロインスポンジの表面にも3〜5層の軟骨様組織が積層していた.又,細胞播種量は1日目が3個/pore程度であったが,7日目には10個/poreとなった.全ての軟骨様組織で良好なサフラニンO染色性が観察され,トルイジンブルー染色で異染性が確認できた.collagen免疫染色ではtype IIが陽性,type Iは陰性であった.又,Pin-peeling tensile testを行ったところ,培養に伴う強度の上昇を認め,14日目にはコラーゲンゲル播種群と比較して17倍の強度を示した
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The Journal of Veterinary Medical Science 64(10) 933-936 2002年10月
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The Journal of Veterinary Medical Science 64(9) 863-866 2002年9月
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日本バイオマテリアル学会大会予稿集 シンポジウム2000 164-164 2000年11月
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日本臨床バイオメカニクス学会誌 = Proceedings of ... Annual Meeting of Japanese Society for Clinical Biomechanics and Related Research 21 427-432 2000年10月1日
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獣医麻酔外科学雑誌 31(Suppl.1) 116-116 2000年7月
担当経験のある科目(授業)
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共同研究・競争的資金等の研究課題
3-
日本学術振興会 科学研究費助成事業 2012年4月 - 2015年3月