Curriculum Vitaes
Profile Information
- Affiliation
- 准教授, 獣医学部, 日本獣医生命科学大学
- Degree
- 博士(獣医学)(東京大学)
- J-GLOBAL ID
- 201501014744797435
- researchmap Member ID
- B000250308
- External link
Research Interests
23Research Areas
1Research History
6-
Apr, 2016 - Present
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Apr, 2012 - Mar, 2015
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Apr, 2007 - Mar, 2012
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Apr, 2006 - Mar, 2007
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Apr, 2004 - Mar, 2006
Committee Memberships
3-
Sep, 2019 - Present
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Oct, 2017 - Present
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Apr, 2017 - Present
Awards
1-
Apr, 2014
Papers
139-
Journal of Comparative Pathology, 210 8-14, Apr, 2024
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The Canadian veterinary journal = La revue veterinaire canadienne, 65(3) 227-233, Mar, 2024A stray cat, an intact female Japanese domestic shorthair cat of unknown age (suspected to be a young adult), was rescued. The cat was lethargic and thin and had marked skin fragility, delayed wound healing without skin hyperextensibility, and hind limb proprioceptive ataxia and paresis. Survey radiography, computed tomography, and magnetic resonance imaging revealed congenital vertebral anomalies, including thoracolumbar transitional vertebrae, scoliosis resulting from a thoracic lateral wedge-shaped vertebra, and a kinked tail, and a dilated spinal cord central canal. Through nutritional support, the cat's general condition normalized, followed by a gradual and complete improvement of skin features. Whole-genome sequencing was completed; however, no pathogenic genetic variant was identified that could have caused this phenotype, including congenital scoliosis. A skin biopsy obtained 7 y after the rescue revealed no remarkable findings on histopathology or transmission electron microscopy. Based on clinical course and microscopic findings, malnutrition-induced reversible feline skin fragility syndrome (FSFS) was suspected, and nutritional support was considered to have improved the skin condition. Key clinical message: This is the second reported case of presumed malnutrition-induced reversible FSFS and was accompanied by long-term follow-up.
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International Journal of Molecular Sciences, Dec 14, 2023
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Journal of Veterinary Diagnostic Investigation, Oct 2, 2023A 9-y-old male Boxer dog developed a mandibular skin tumor, which histologically had a locally invasive growth pattern composed of bilayered structures of inner eosinophilic cuboidal tumor cells and outer clear polygonal tumor cells with cytoplasm containing glycogen granules. Both cell populations gradually changed from low-grade morphologic features to highly anaplastic ones. Immunohistochemically, the eosinophilic tumor cells were positive for cytokeratin 8, a useful marker for luminal epithelial cells. In contrast, the clear tumor cells expressed several myoepithelial markers, including α-smooth muscle actin, p63, and cytokeratin 14. Based on these histologic and immunohistochemical characteristics, we diagnosed this apocrine sweat gland tumor as a carcinoma-and-malignant myoepithelioma with high-grade transformation of both luminal and myoepithelial cells. Our case may be a helpful reference for the histogenesis of carcinoma-and-malignant myoepithelioma, in which both the luminal epithelial and myoepithelial components are malignant.
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Frontiers in Veterinary Science, 10, Apr, 2023 Peer-reviewed
Misc.
38Books and Other Publications
1Presentations
44Professional Memberships
3Research Projects
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Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Apr, 2022 - Mar, 2025
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Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Apr, 2021 - Mar, 2024
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Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Apr, 2019 - Mar, 2022
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基盤研究(B), Apr, 2015 - Mar, 2018
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Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Apr, 2014 - Mar, 2017