Curriculum Vitaes
Profile Information
- Affiliation
- Associate Professor, Faculty of Veterinary Science School of Veterinary Medicine, Nippon Veterinary and Life Science University
- Degree
- 修士(法学)(上智大学)博士(獣医学)(日本獣医生命科学大学)
- J-GLOBAL ID
- 200901067948482741
- researchmap Member ID
- 6000001295
Research Areas
3Education
3Papers
29-
Veterinary Nursing, 28(1) 1-8, 2023 Peer-reviewedCorresponding author
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Veterinary Nursing, 19(2) 15-21, 2014 Peer-reviewedRehabilitation is drawing more and more attention as a therapeutic practice, also in veterinary surgery. In this study, we performed post-operative rehabilitation on a dog which had gone through tibial-plateau-leveling osteotomy(TPLO), and whose treatment had been complicated by cranial cruciate ligament rupture and cauda equina syndrome. We then examined the usefulness of rehabilitation. We performed icing, passive range-of- motion(PROM)exercise, massotherapy, hyperthermia and hydropathy on the dog from the postoperative early stage. The results revealed that the range of joint motion and the muscle mass decreased less than in the control dogs. Time to recovery of walking, analyzed with the force plate, was two months, which was shorter than in the control dogs, which was three months. Collectively, we suggest that the rehabilitation at the early stage is effective in accelerating postoperative recovery. We hope that rehabilitation will become more common in veterinary medicine also in Japan, and it will be helpful for patient animals to become free of paralysis and/or pain, and to reduce the suffering of owners.
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Journal of Artificial Organs, 14 133-139, 2011 Peer-reviewed
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Research in Veterinary Science, 90(3) 396-403, 2011 Peer-reviewedInsulin detemir is the first member of a new class of long-acting soluble insulin analogues capable of maintaining the basal level of insulin in humans. In this preliminary study, we investigated the time-action profiles of insulin detemir in normal and diabetic dogs since the use of insulin detemir in canines has yet to be determined. Eight animals were used in our study (three normal and five insulin dependent diabetic dogs). Time-action profiles of insulin detemir were monitored in normal dogs using an artificial pancreas apparatus under euglycemic condition. Blood sampling was performed at 2. h intervals post feeding, with insulin administration, in insulin dependent diabetic dogs. Time-action profiles of insulin detemir, in normal dogs, demonstrated that insulin detemir is a long-lasting preparation similar to what has been observed in humans. A pronounced peak was detected at 8-10. h while the glucose-lowering effect lasted for over 24. h after insulin injection, thus illustrating its longer prolonged peak activity time. Furthermore, intensive glycemic control was achieved with insulin detemir in insulin dependent diabetic dogs, using a lower dosage than NPH insulin and insulin glargine therapeutic doses. Our results indicate that insulin detemir has a greater effect than either NPH insulin or insulin glargine in canines, requiring a lower dose than either insulin preparation. However, using insulin detemir also carries a higher risk of inducing hypoglycemia as compared to either NPH insulin or insulin glargine. © 2010 Elsevier Ltd.
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Veterinary Research Communication, 34(2) 161-172, 2010 Peer-reviewedIndigestible oligosaccharides have been shown to normalize blood glucose and insulin concentration thereby promoting good health and preventing diseases, such as diabetes. Transglucosidase (TG, a-glucosidase, enzyme code (EC) 3.2.1.20) is an enzyme capable of converting starch to oligosaccharides, such as iso-malto-oligosaccharides from maltose, via the action of amylase. The aim of this study was to evaluate whether oral administration of TG with maltose or dextrin is capable of reducing post-prandial serum glucose concentration in experimentally streptozotocin (STZ)-induced diabetic dogs fed on a high-fiber diet. Five healthy and five STZ-induced diabetic dogs were employed in this study. TG supplementation with dextrin or maltose had no detrimental effect in healthy dogs. In fact, TG and dextrin exhibited a flatlined serum glucose pattern, while reducing mean post-prandial serum insulin and glucose concentration as compared to control diet alone. When TG supplementation was tested in STZ-induced diabetic dogs under the context of a high fiber diet, a 13.8% and 23.9% reduction in mean glucose concentration for TG with maltose and dextrin, respectively was observed. Moreover, TG with dextrin resulted in a 13% lower mean post-prandial glucose concentration than TG with maltose, suggesting that dextrin may be a more efficient substrate than maltose when used at the same concentration (1 g/kg). Our results indicate that TG supplementation with diet can lead to lower postprandial glucose levels versus diet alone. However, the efficacy of TG supplementation may depend on the type of diet it is supplemented with. As such, TG administration may be useful for preventing the progression of diabetes mellitus and in its management in dogs. © 2010 Springer Science+Business Media B.V.
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日本比較臨床医学会誌, 17(2) 102-118, 2009 Peer-reviewedLead authorLast authorCorresponding author
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Journal of Comparative Clinical Medicine, 16(1) 5-8, 2008 Peer-reviewedLead authorLast authorCorresponding author
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日本比較臨床医学会誌, 16(2) 38-46, 2008 Peer-reviewedLead authorLast authorCorresponding author
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Journal of Comparative Clinical Medicine, 15(1) 14-22, 2007 Peer-reviewedLead authorLast authorCorresponding author
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上智法学論集, 48(3・4) 223-241, 2005 Peer-reviewedLead authorLast authorCorresponding author
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Journal of Comparative Clinical Medicine, 12(3) 36-37, 2004 Peer-reviewed
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Journal of Comparative Clinical Medicine, 12(1) 33-35, 2004 Peer-reviewed
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Journal of Comparative Clinical Medicine, 12(1) 18-25, 2004 Peer-reviewedLead authorLast authorCorresponding author
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International Journal of Food Microbiology, 74 87-99, 2002 Peer-reviewed
Misc.
1Books and Other Publications
12Presentations
7Teaching Experience
16-
Sep, 2015 - Present獣医事法規 (日本大学)
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2015 - Present獣医療倫理・動物福祉学 (麻布大学)
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Apr, 2011 - Present獣医学概論 (麻布大学)
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2010 - Present総合獣医学 (麻布大学)
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Apr, 2006 - Present動物保健看護関連法規 (日本獣医生命科学大学)
Research Projects
3-
その他の研究制度, 2000