Curriculum Vitaes
Profile Information
- Affiliation
- Professor, Faculty of Veterinary Science, School of Veterinary Medicine, Nippon Veterinary and Life Science University
- Degree
- (BLANK)
- J-GLOBAL ID
- 200901042480063069
- researchmap Member ID
- 1000093613
Research Interests
6Research Areas
1Education
2Committee Memberships
2-
- Present
Papers
76-
Veterinary medicine and science, 10(3) e1456, May, 2024BACKGROUND: Few epidemiological studies on respiratory medicine and the relationship between clinical signs and various respiratory diseases in cats have been reported. OBJECTIVES: This retrospective study aimed to investigate the prevalence and breed predisposition to feline respiratory diseases in Japan and determine the association between clinical signs, duration and type of respiratory diseases. METHODS: The medical records of cats with feline respiratory diseases were examined to obtain information on age, sex, breed, final diagnosis, clinical signs and duration. The odds ratios (ORs) and 95% confidence intervals were calculated to evaluate breed predispositions. Mann-Whitney U, Kruskal-Wallis and Dunn's tests were used to assess the duration of clinical signs. RESULTS: This study included 540 cats with 615 respiratory diagnoses. The American Shorthair breed was predisposed to bronchopneumonia (BP; OR: 5.0) and pulmonary tumour (PT; OR: 3.6), while the Russian Blue breed exhibited a predisposition to inflammatory lower airway diseases (OR: 3.4), BP (OR: 6.1) and interstitial lung diseases (OR: 11.1). Similarly, the Scottish Fold breed displayed predisposition to PTs (OR: 5.8). The duration of clinical signs among nasal diseases, nasopharyngeal diseases and lower tracheal/bronchial and pulmonary diseases differed significantly (p = 0.001, p = 0.012, p < 0.0001, respectively). CONCLUSIONS: The results suggest that some popular breeds in Japan are predisposed to feline respiratory diseases, especially the American Shorthair, Russian Blue and Scottish Fold breeds. The characteristics of occurrence, clinical signs and duration of each disease will aid in diagnosing, treating, preventing and elucidating the pathophysiology of feline respiratory disease.
-
Journal of Animal Clinical Medicine, 32(4) 152-156, Dec, 2023 Peer-reviewed
-
Veterinary medicine and science, 9(2) 638-644, Oct 17, 2022BACKGROUND: Few studies have investigated the incidence of respiratory diseases based on anatomical sites or the relationship between breed and these diseases. OBJECTIVE: The objective of this study was to investigate the prevalence of canine respiratory diseases among dogs in Japan, with relationship to the breed. METHODS: We retrospectively reviewed the medical records of dogs with respiratory symptoms and calculated the odds ratio (OR) to evaluate the relationship between breed and disease. RESULTS: A total of 1050 dogs with respiratory symptoms were included in this study. Miniature dachshunds were the most common breed affected by respiratory diseases. Among tracheobronchial diseases, there was a significant association between some small breeds and tracheobronchial collapse, miniature dachshunds (OR: 4.44, 8.43, 95% confidence interval [CI]: 3.17-6.22, 4.33-16.0) and chronic bronchitis and bronchiectasis. Among nasal diseases, miniature dachshunds (OR: 27.2, 95% CI: 16.8-44.8) and golden retrievers (OR: 21.0, 95% CI: 6.43-69.3) were the most affected by non-infectious rhinitis and nasal aspergillosis, respectively. Brachycephalic obstructive airway syndrome was the most common disease among pharyngeal and laryngeal diseases, with a relationship with breed being found in some brachycephalic breeds, and Pomeranians (OR: 2.7, 95% CI: 1.42-5.17). CONCLUSIONS: Respiratory diseases in dogs are strongly correlated with popular breeds in Japan. Miniature dachshunds, in particular, are associated with many respiratory diseases, which may differ from international reports. Thus, this result may help in the early detection, prevention, treatment, and elucidation of the pathophysiology of canine respiratory diseases.
-
Journal of Animal Clinical Medicine, 31(3) 106-111, Sep, 2022 Peer-reviewed
-
Journal of Feline Medicine and Surgery Open Reports, 8(1) 205511692210742-205511692210742, Jan, 2022<sec><title>Case summary</title> A 4-year-old castrated male domestic shorthair cat with a continuous cough was brought to a private veterinary clinic for detailed examination. Radiography of the thoracic cavity revealed a severe radiopaque region in the caudal lobe of the right lung. At 108 days after the initial visit, CT showed a mass of 27 × 23 × 18 mm in the caudal lobe of the right lung. At that time, no abnormalities in other organs except for the lung were detected on CT and peripheral blood and blood biochemistry tests. The mass in the caudal lobe of the right lung was resected by lobectomy; it had a white surface and was firm. Histopathologically, the mass was non-encapsulated, showing an unclear boundary with surrounding tissues. The mass comprised large, round or polygonal neoplastic cells arranged in a diffuse pattern. Immunohistochemically, neoplastic cells were diffusely positive for CD20, feline leukaemia virus (FeLV) p27 and FeLV glycoprotein 70 but negative for CD3, CD204 and E-cadherin. Based on these findings, diffuse large B-cell lymphoma associated with FeLV infection was diagnosed. Although the cat showed no clinical signs of gastrointestinal or respiratory injury, a routine ultrasonography revealed thickening in the jejunum wall 196 days after lobectomy, and subsequent fine-needle aspiration examination confirmed high-grade lymphoma. </sec><sec><title>Relevance and novel information</title> This is the first report of primary pulmonary diffuse large B-cell lymphoma associated with FeLV infection in a young cat. </sec>
Misc.
96-
獣医麻酔外科学雑誌 = Japanese journal of veterinary anesthesia & surgery, 36 265-266, Jun 20, 2005
-
獣医麻酔外科学雑誌 = Japanese journal of veterinary anesthesia & surgery, 36 263-264, Jun 20, 2005
-
日本獣医畜産大学研究報告, 53 86-87, Dec 1, 2004
-
獣医麻酔外科学雑誌 = Japanese journal of veterinary anesthesia & surgery, 35 203-203, Jun 20, 2004
-
獣医麻酔外科学雑誌 = Japanese journal of veterinary anesthesia & surgery, 35 205-205, Jun 20, 2004
-
獣医麻酔外科学雑誌 = Japanese journal of veterinary anesthesia & surgery, 35 208-208, Jun 20, 2004
-
獣医麻酔外科学雑誌 = Japanese journal of veterinary anesthesia & surgery, 35 206-207, Jun 20, 2004
-
JOURNAL OF SMALL ANIMAL PRACTICE, 45(1) 29-31, Jan, 2004Tracheal narrowing is described in two cats. In both cases, inspiratory radiographs demonstrated tracheal narrowing just cranial to the thoracic inlet; no narrowing was seen on expiratory radiographs. Magnetic resonance imaging revealed suspected nasal tumours in both cases, but no abnormalities were identified in the region of the narrowed trachea. Nasal biopsy confirmed intranasal lymphoma in one cat and nasal adenocarcinoma in the other. The former cat was treated with chemotherapy. The owner of the latter cat declined further treatment. The tracheal narrowing disappeared after the initiation of chemotherapy in the cat with intranasal lymphoma and it is suggested that the narrowing might have been associated with the nasal tumour. A careful evaluation of the airway, especially cranial to the narrowing, is recommended in cases of tracheal narrowing in cats.
-
Japanese Journal of Veterinary Anesthesia & Surgery, 33(2) 25-31, 2002
-
獣医麻酔外科学雑誌 = Japanese journal of veterinary anesthesia & surgery, 32 300-301, Jul 1, 2001
-
獣医麻酔外科学雑誌 = Japanese journal of veterinary anesthesia & surgery, 32 275-277, Jul 1, 2001
-
Japanese journal of veterinary anesthesia & surgery, 30(3) 55-60, Jul 31, 1999
-
獣医麻酔外科学雑誌 = Japanese journal of veterinary anesthesia & surgery, 29 50-50, Oct 10, 1998
-
獣医麻酔外科学雑誌 = Japanese journal of veterinary anesthesia & surgery, 29 51-51, Oct 10, 1998
-
獣医麻酔外科学雑誌 = Japanese journal of veterinary anesthesia & surgery, 27 100-100, Oct 20, 1996
-
Journal of the Japan Veterinary Medical Association, 49(9) 655-657, Sep 20, 1996
-
獣医麻酔外科学雑誌 = Japanese journal of veterinary anesthesia & surgery, 27 78-78, Jun 1, 1996
-
JOURNAL OF VETERINARY MEDICAL SCIENCE, 57(3) 395-399, Jun, 1995Chlormadinone acetate (GS implant(R), CMA) pellet, a synthetic luteal hormone preparation, Was Subcutaneously implanted at 5, 10 and 20 mg/kg in four normal male dogs ranging in age from 3 to 10 years to determine the changes in the prostatic volume, peripheral plasma levels of sex hormones and semen quality. The plasma levels of CMA, LH, testosterone (T) and 5 alpha-dihydrotestosterone (DHT) were measured by radioimmunoassay. The prostatic volume was measured by computed tomography. The semen was collected by digital manipulation. The pellet was removed 26 weeks after implantation. The effects of CMA pellet implantation were examined during implantation and until 22 weeks after removal.:The prostatic volume was reduced to 61+/-3 (mean +/-S.E., n=4), 52+/-5 (n=4) and 53+/-9 (n=4)% of the preimplantation volumes in the 5, 10 and 20 mg/kg groups, respectively. The plasma CMA levels in the 10 mg/kg and 20 mg/kg groups peaked at 2 weeks, but were gradually decreased. At 22 weeks after removal of the pellet, the prostatic volume returned to 74-85% of the preimplantation volumes. The plasma LH levels tended to increase after implantation in all groups. The plasma T and DHT levels were slightly decreased in all groups. In the 10 and 20 mg/kg groups, the number of sperm and motility sperm was reduced, and the rate of abnormal sperm increased. These findings indicated that implantation of a CMA-pellet at a dose of 10 mg/kg or more decreases the prostatic volume to 1/2 the original size and retains its effect for a long time, although it depresses gonadal function. The present study suggested that CMA implantation is useful in treating benign prostatic hyperplasia.
-
獣医麻酔外科学雑誌 = Japanese journal of veterinary anesthesia & surgery, 26 59-59, May 1, 1995
-
獣医麻酔外科学雑誌 = Japanese journal of veterinary anesthesia & surgery, 26 65-65, May 1, 1995
-
獣医麻酔外科学雑誌 = Japanese journal of veterinary anesthesia & surgery, 26 60-60, May 1, 1995
-
VETERINARY RADIOLOGY & ULTRASOUND, 35(2) 79-82, Mar, 1994The biliary opacification characteristics and toxicity of meglumine iotroxate (Biliscopin) were studied in twenty-three normal cats. Intravenous administration of 72 mg/kg of Biliscopin resulted in opacification of the gallbladder and bile duct 20 minutes after administration. Licking and vomiting appeared in ten of twelve cats immediately after administration. These side-effects were abolished by administration of an anti-histaminic agent. Slight elevation in ALT or AST was detected 24 hours after administration of Biliscopin. These findings suggest that Biliscopin can be used safely in the cat.
-
The journal of veterinary medical science, 56(4) 791-794, 1994Computed tomography after myelography (CTM) was performed pre- and postoperatively on four dogs diagnosed as having Cervical intervertebral disc protrusion. The surgery was performed by ventral slot technique in all the cases. The direction of the ventral slot was precisely adjusted according to the location of the protruded discs as seen on CTM. Postoperative values for the transversal area of the spinal cord were greater than those measured preoperatively, suggesting effective decompression of the cord. The prognosis for these patients was excellent. In view of these results, it was considered that preoperative confirmation of the positional relationship between the spinal cord and the protruded disc by CTM was quite useful in planning the surgical technique for disc disease in the dog.
-
The Journal of Veterinary Medical Science., 56(5) 817-822, 1994The clinical usefulness of biodegradable oriented poly-L-lactide (PLLA) screws for experimental Salter-Harris type 4 fracture in the distal femoral condyle of dogs was evaluated. Bony union of the osteotomized fragment of the condyle was almost completed radiographically and histologically within 1 to 2 months after surgery, suggesting that PLLA screws maintained strength long enough to fix the fragment until bone healing. At 4 to 6 months after surgery, minute fissures were histologically confirmed on the surface of the screw thread, suggesting the early stage of biodegradation and absorption of the polymer. During the observational period, no significant difference between the treated femur and the contralateral non-treated femur in either total femoral length or maximum condyle width was observed, indicating no growth disturbance in the treated femur. From these results it was concluded that the PLLA screw might be an ideal implant for the reduction and fixation of epiphyseal plate fractures such as Salter-Harris type 3 or type 4 fractures.
-
JOURNAL OF VETERINARY MEDICAL SCIENCE, 53(6) 1081-1082, Dec, 1991
-
JOURNAL OF VETERINARY MEDICAL SCIENCE, 53(4) 749-751, Aug, 1991
-
JOURNAL OF VETERINARY MEDICAL SCIENCE, 53(1) 123-124, Feb, 1991
-
Japanese journal of veterinary science, 51(3) 646-648, Jun 15, 1989
Books and Other Publications
19Teaching Experience
4Professional Memberships
4Research Projects
5-
Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Apr, 2019 - Mar, 2023
-
科学研究費助成事業, 日本学術振興会, 2004 - 2006