Curriculum Vitaes
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Journal of Feline Medicine and Surgery Open Reports, 8(1) 205511692210742-205511692210742, Jan, 2022<sec><title>Case summary</title> A 4-year-old castrated male domestic shorthair cat with a continuous cough was brought to a private veterinary clinic for detailed examination. Radiography of the thoracic cavity revealed a severe radiopaque region in the caudal lobe of the right lung. At 108 days after the initial visit, CT showed a mass of 27 × 23 × 18 mm in the caudal lobe of the right lung. At that time, no abnormalities in other organs except for the lung were detected on CT and peripheral blood and blood biochemistry tests. The mass in the caudal lobe of the right lung was resected by lobectomy; it had a white surface and was firm. Histopathologically, the mass was non-encapsulated, showing an unclear boundary with surrounding tissues. The mass comprised large, round or polygonal neoplastic cells arranged in a diffuse pattern. Immunohistochemically, neoplastic cells were diffusely positive for CD20, feline leukaemia virus (FeLV) p27 and FeLV glycoprotein 70 but negative for CD3, CD204 and E-cadherin. Based on these findings, diffuse large B-cell lymphoma associated with FeLV infection was diagnosed. Although the cat showed no clinical signs of gastrointestinal or respiratory injury, a routine ultrasonography revealed thickening in the jejunum wall 196 days after lobectomy, and subsequent fine-needle aspiration examination confirmed high-grade lymphoma. </sec><sec><title>Relevance and novel information</title> This is the first report of primary pulmonary diffuse large B-cell lymphoma associated with FeLV infection in a young cat. </sec>
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Veterinary pathology, 57(3) 432-436, May, 2020A 10-year-old female Papillon dog that had previously developed a mammary tumor was admitted for treatment of a hypoglycemic attack. Blood examination showed severe hypoglycemia and decreased blood insulin concentration. Computed tomography indicated multiple tumors in the cranial and caudal lobes of the right lung. These tumors were resected surgically and diagnosed as pulmonary adenocarcinomas by histopathologic examination. Hypoglycemia was temporarily improved after the resection, but a hypoglycemic event occurred 2 months after the surgery. Immunohistochemistry of the tumor demonstrated the expression of insulin-like growth factor 2 in tumor cells. Western blot analysis revealed the expression of high-molecular-weight (big)-insulin-like growth factor 2 in the tumor region. Insulin-like growth factor 2 mRNA expression was also confirmed in the tumor using reverse transcription-polymerase chain reaction. These findings indicate the diagnosis of non-islet cell tumor-induced hypoglycemia caused by big-insulin-like growth factor 2 produced by the tumor in the dog. This report provides information on differentiating tumors that cause paraneoplastic hypoglycemia.
Misc.
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動物臨床医学, 25(1) 026-030, Mar, 2016術後創部の異常を早期に発見するためには、創部の疼痛や不快感などが重要な情報となる。しかし、動物看護においては、動物から症状の訴えを得ることは困難である。そのため、客観的な観察から早期に異常を発見することが求められる。そこで今回、外科手術後の看護動物2事例を対象とし、治療経過とともにサーモグラフィを用いた創部の観察を行った。その結果、1事例においては、腫脹・発赤を認めた創部がサーモグラフィ上で周辺部より高温を示し、肉眼的に炎症が消失し治癒が進行するに従い、創周囲との温度差が減少し均一な温度分布となった。また、2事例目では、創部に形成された潰瘍内において、組織が壊死している領域が低温を示し、創状態が悪化していることが確認された。以上、創部に炎症所見を認めた2事例に対して撮影を行うことで、創の状態を継続的にモニタリングすることができ、術後の創傷治癒過程の観察、創部の予後予測にサーモグラフィを用いることができる可能性が示された。(著者抄録)