現代教養学部
Profile Information
- Affiliation
- Professor, School of Arts and Sciences, Division of Mathematical Sciences, Department of Information and Sciences, Tokyo Woman's Christian University
- Degree
- B.Sc.(The University of Tokyo)理学士(東京大学)M.Sc.(The University of Tokyo)理学修士(東京大学)Ph.D.(The University of Tokyo)博士(理学)(東京大学)
- Researcher number
- 90281641
- J-GLOBAL ID
- 201401055520065170
- researchmap Member ID
- 7000008312
- External link
Research Interests
1Research History
7-
Sep, 2005 - Mar, 2017
-
Apr, 2000 - Aug, 2005
-
Mar, 1996 - Mar, 2000
-
May, 1995 - Feb, 1996
Education
3-
Apr, 1989 - Mar, 1992
-
Apr, 1987 - Mar, 1989
-
Apr, 1983 - Mar, 1987
Committee Memberships
8Papers
80-
Biophysics and Physicobiology, 21 e210007_1-e210007_10, Jan, 2024 Peer-reviewedCorresponding author
-
Chemical Physics, 111883-111883, Mar, 2023 Peer-reviewedLead authorCorresponding author
-
Journal of Computer Chemistry, Japan, 21(4) 94-95, 2022 Peer-reviewedInvitedLast authorCorresponding author
-
Chemistry Letters, 50(7) 1325-1328, Jul 5, 2021 Peer-reviewed
-
Journal of Computational Chemistry, Japan, 19(4) 161-163, Apr 13, 2021 Peer-reviewedInvitedMolecular dynamics (MD) simulations were used to analyze the effect of the odorant molecule eugenol on the olfactory receptor protein mOR-EG and the dynamic correlation between amino acid residues around the binding site due to ligand binding. When eugenol hydrogen-bonded with Ser 113 of mOR-EG, the dynamic correlation with amino acid residues 213-218 on the adjacent α-helix increased within 10 ps. In particular, the correlation between Ser 113 and Leu 217 showed characteristic oscillations between 10 ps and 30 ps. The correlation with Leu 217 shifted toward residues closer to the G protein over time. Correlation with amino acids on the other side of the membrane was also observed, suggesting the contribution of collective protein motion.
Misc.
4-
京都大学学術情報メディアセンター広報・全国共同利用版, 14(2) 8-9, Mar, 2016 Invited
-
Meeting Abstracts of the Physical Society of Japan, 62(2) 346-346, 2007
Books and Other Publications
3Presentations
17-
The 104th CSJ Annual Meeting (2024), Mar 18, 2024
-
The 104th CSJ Annual Meeting (2024), Mar 18, 2024
Teaching Experience
30Professional Memberships
4Research Projects
13-
Apr, 2019 - Mar, 2022
-
Apr, 2014 - Mar, 2019
-
Apr, 2014 - Mar, 2017
-
Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Apr, 2010 - Mar, 2014
-
Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Nov, 2008 - Mar, 2014