医学部
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  2. kondo yasuto

kondo yasuto

  (近藤 康人)

Profile Information

Affiliation
Professor, Department of Pediatrics, Fujita Health University School of Medicine, Fujita Health University
副センター長, 総合アレルギーセンター
Degree
博士(医学)(藤田保健衛生大学)
J-GLOBAL ID
200901050027932873
researchmap Member ID
1000360715

Research Areas

 1

Awards

 1

Papers

 179
  • 岡本 薫, 西山 里穂, 杉田 晃, 西本 早希, 河野 透哉, 杉本 えり那, 井上 博貴, 水谷 公美, 森 雄司, 大久保 悠里子, 中島 陽一, 近藤 康人, 吉川 哲史
    日本小児科学会雑誌, 128(2) 205-205, Feb, 2024  
  • 西本 早希, 森 雄司, 杉田 晃, 水谷 公美, 近藤 康人, 河野 透哉, 杉本 えり那, 岡本 薫, 大久保 悠里子, 中島 陽一
    子どもの健康科学, 25(1) 29-37, Jan, 2024  
    【背景・目的】学校では教職員が複数児童の対応を同時に行うため、食物アレルギーに関するインシデントが起きやすい。2014年度に文部科学省から「学校給食における食物アレルギー対応指針」(以下、対応指針)が発表されたが、対応指針発表の前後におけるインシデント発生の背景因子を検証した報告はないため、今回我々は検討した。【方法】2015年度から2019年度に食物アレルギー講習会に参加した教員や保護者へ手渡し、あるいはアレルギー支援ネットワークのホームページのインシデント事例入力サイトや患者会への郵送などを通して、インシデント事例のアンケートを実施した。その中から教育施設に関する事例について対応指針発表前(15件)と発表後(28件)の2群に分けて、原因食品、誘発症状、発症状況、給食の対応レベル、生活管理指導表の提出状況、発症原因を調査した。【結果】インシデント事例の原因食品については鶏卵の割合が減り、発症状況については給食中が最多で変化はなかった。給食の対応レベルで「完全除去」よりも「一部弁当」や「普通食」の報告が増えていた。発症の原因として「完全除去」での「調理中のアレルゲン混入」の報告は減っていたが「配膳ミス」の報告は継続していた。運動誘発による事例が対応指針発表後、新たに報告され、昼食後の体育や遊び時間での発症が多く、重篤な症状も多く報告されていた。【結論】対応指針発表後もインシデントの背景因子として「配膳ミス」が報告されていることから、「配膳ミス」を防ぐ取り組みの推進と、新たな課題として食物依存性運動誘発アナフィラキシーの認知度を教育関係者に高める啓発活動が必要であると考えた。(著者抄録)
  • Chisato Inuo, Hitoshi Ando, Kenichi Tanaka, Yoichi Nakajima, Ikuya Tsuge, Atsuo Urisu, Yasuto Kondo
    International archives of allergy and immunology, 1-6, Oct 18, 2023  
    BACKGROUND: Allergen-specific immunotherapy (AIT), an established treatment for allergic diseases, prevents the development of other allergic manifestations. Although the mechanisms remain unclear, AIT has been shown to reduce basophil activation (BA) against nontarget allergens. OBJECTIVES: The aim of this study was to assess immunological changes in Dermatophagoides farinae (Der f) after Japanese cedar pollen (JCP)-based subcutaneous immunotherapy (SCIT) monotherapy. METHOD: The data of 16 patients (age: 6-37 years) with JCP-induced allergic rhinitis who were sensitive to Der f (serum Der f-specific immunoglobulin E [IgE] level >0.34 kUA/L) and received JCP-based SCIT for 5 years were reviewed retrospectively. BA by Der f and JCP extracts and serum-specific IgE and immunoglobulin G4 (IgG4) levels against these allergens were evaluated before and after completing 5 years of JCP-based SCIT monotherapy. RESULTS: The areas under the dose-response curves of BA by Der f and JCP extracts were significantly reduced (p = 0.02 and p = 0.002, respectively). JCP-specific IgE levels decreased and JCP-specific IgG4 levels increased significantly (p < 0.001 for both), whereas Der f-specific IgE and IgG4 levels did not change significantly. CONCLUSIONS: JCP-based SCIT monotherapy reduced Der f-specific BA. These findings suggest that JCP-based SCIT has the potential to modulate immune response toward nontarget allergens.
  • 森 雄司, 杉田 晃, 河野 透哉, 杉本 えり那, 西本 早希, 岡本 薫, 水谷 公美, 中島 陽一, 近藤 康人
    日本小児アレルギー学会誌, 37(4) 370-370, Oct, 2023  
  • 水谷 公美, 杉田 晃, 河野 透哉, 岡本 薫, 森 雄司, 大久保 悠里子, 田中 健一, 中島 陽一, 宇理須 厚雄, 近藤 康人
    日本小児アレルギー学会誌, 37(4) 394-394, Oct, 2023  
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Misc.

 606
  • 岡本薫, 加藤えり那, 齋藤彩子, 安田泰明, 水谷公美, 森雄司, 川井学, 藤井里奈, 大久保悠里子, 中島陽一, 近藤康人, 吉川哲史
    日本小児科学会雑誌, 124(2), 2020  
  • 齋藤彩子, 齋藤彩子, 森雄司, 森雄司, 青木祐治, 青木祐治, 長谷川英里香, 長谷川英里香, 河野透哉, 河野透哉, 加藤えり那, 安田泰明, 岡本薫, 岡本薫, 水谷公美, 水谷公美, 川井学, 川井学, 中島陽一, 中島陽一, 中村政志, 中村政志, 松永佳世子, 近藤康人, 近藤康人
    日本小児アレルギー学会誌(Web), 34(4), 2020  
  • 近藤康人, 近藤康人, 森雄司, 森雄司, 湯浅智子
    小児耳鼻咽喉科, 41(2), 2020  
  • 近藤康人, 中島陽一, 森雄司, 安田泰明, 岡崎史子, 成田宏史, 下條尚志, 松永佳世子, 森山達哉
    日本小児アレルギー学会誌(Web), 34(1), 2020  
  • Motohiro Ebisawa, Komei Ito, Takao Fujisawa, Yukoh Aihara, Setsuko Ito, Takanori Imai, Yusei Ohshima, Yukihiro Ohya, Hideo Kaneko, Yasuto Kondo, Naoki Shimojo, Mizuho Nagao, Yasunori Ito, Yuzaburo Inoue, Ikuo Okafuji, Sakura Sato, Yoichi Nakajima, Hajime Nishimoto, Tatsuki Fukuie, Masaki Futamura, Tetsuharu Manabe, Noriyuki Yanagida, Yoshiyuki Yamada, Atsuo Urisu
    Allergology International, 2020  
    © 2020 Japanese Society of Allergology Five years have passed since the Japanese Pediatric Guideline for Food Allergy (JPGFA) was first revised in 2011 from its original version. As many scientific papers related to food allergy have been published during the last 5 years, the second major revision of the JPGFA was carried out in 2016. In this guideline, food allergies are generally classified into four clinical types: (1) neonatal and infantile gastrointestinal allergy, (2) infantile atopic dermatitis associated with food allergy, (3) immediate-type of food allergy (urticaria, anaphylaxis, etc.), and (4) special forms of immediate-type of food allergy such as food-dependent exercise-induced anaphylaxis and oral allergy syndrome (OAS). Much of this guideline covers the immediate-type of food allergy that is seen during childhood to adolescence. Infantile atopic dermatitis associated with food allergy type is especially important as the onset of most food allergies occurs during infancy. We have discussed the neonatal and infantile gastrointestinal allergy and special forms of immediate type food allergy types separately. Diagnostic procedures are highlighted, such as probability curves and component-resolved diagnosis, including the recent advancement utilizing antigen-specific IgE. The oral food challenge using a stepwise approach is recommended to avoid complete elimination of causative foods. Although oral immunotherapy (OIT) has not been approved as a routine treatment by nationwide insurance, we included a chapter for OIT, focusing on efficacy and problems. Prevention of food allergy is currently the focus of interest, and many changes were made based on recent evidence. Finally, the contraindication between adrenaline and antipsychotic drugs in Japan was discussed among related medical societies, and we reached an agreement that the use of adrenaline can be allowed based on the physician's discretion. In conclusion, this guideline encourages physicians to follow the principle to let patients consume causative foods in any way and as early as possible.
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Presentations

 84
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Professional Memberships

 7
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Research Projects

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