医療科学部

金子 千之

kaneko chiyuki

基本情報

所属
藤田医科大学 医療科学部 臨床検査学科 形態・細胞検査学 講師
学位
博士(医学)

J-GLOBAL ID
200901009977885332
researchmap会員ID
1000102773

MISC

 103
  • KANEKO Chiyuki, KATO Yoshimitsu, YANAGIDA Takamasa, ABE Masato, KOSUGE Yuuko, IWAI Muneo
    Int J Anal Bio-Sci 3(2) 37-40 2015年6月30日  
  • KANEKO Chiyuki, KATO Yoshimitsu, YANAGIDA Takamasa, ABE Masato, KOSUGE Yuuko, IWAI Muneo
    形態・機能 12(2) 75-78 2014年3月25日  
    Helicobacter pylori (H. pylori) is a very important pathogenic bacteria associated with many upper gastrointestinal diseases including chronic active gastritis, chronic inactive gastritis, gastric and duodenal peptic ulcer disease, gastric MALT lymphoma, and gastric adenocarcinoma. There are no distinct endoscopic patterns of chronic H. pylori gastritis. The diagnosis of H. pylori gastritis is made by pathologic examination of gastric mucosal biopsies or by the detection of urease in mucosal specimens using the CLO test or urea breath test.  H. pylori infection has been diagnosed based on the histological laboratory procedure and indirectly from a background gastric-mucous-membrane view. Alcian Yellow Touidine Blue staining is available and useful as one of the diagnostic methods.
  • KANEKO Chiyuki, KOSUGE Yuuko, IWAI Muneo
    生物試料分析 35(4) 342-346 2012年9月30日  
  • Kiyoshi Hasegawa, Kyoko Kawamura, Rina Kato, Shinichi Komiyama, Chiyuki Kaneko, Yasuhiro Udagawa
    ACTA CYTOLOGICA 56(4) 394-400 2012年  
    Objective: We previously reported that oral administration of the selective cyclooxygenase-2 (COX-2) inhibitor etodolac results in antitumor effects in endometrial cancer tissue. Herein, we investigated whether these antitumor effects could be assessed using endometrial cytological findings. Study Design: Etodolac (400 mg b.i.d. for 2 weeks) was administered preoperatively to 21 endometrial cancer patients: 16 had COX-2-positive disease and 5 had COX-2-negative disease. Twenty-one pairs of pre- and post-etodolac-treatment endometrial cytological samples were collected to review changes in the cytological features. Results: In the COX-2-positive patients, nuclear atypia was slightly decreased in 3 of the 16 cases, while the mitotic index was decreased in all cases. Cellular overlapping and tumor cell cluster outlines were somewhat affected in 6 and 8 cases, respectively. Nuclear/cytoplasmic ratio, anisokaryosis and hyperchromasia were also reduced in 6, 4, and 2 cases, respectively; however, tumor diathesis and nucleoli features were unchanged. In contrast, endometrial cytological features did not appear to be affected in the 5 COX-2-negative patients. Conclusions: We conclude that the antitumor effects observed in endometrial cancer tissues following oral administration of etodolac are reflected in and can be easily assessed by evaluating endometrial cytological features. Copyright (c) 2012 S. Karger AG, Basel
  • Kiyoshi Hasegawa, Kyoko Kawamura, Rina Kato, Shinichi Komiyama, Chiyuki Kaneko, Yasuhiro Udagawa
    ACTA CYTOLOGICA 56(4) 394-400 2012年  査読有り
    Objective: We previously reported that oral administration of the selective cyclooxygenase-2 (COX-2) inhibitor etodolac results in antitumor effects in endometrial cancer tissue. Herein, we investigated whether these antitumor effects could be assessed using endometrial cytological findings. Study Design: Etodolac (400 mg b.i.d. for 2 weeks) was administered preoperatively to 21 endometrial cancer patients: 16 had COX-2-positive disease and 5 had COX-2-negative disease. Twenty-one pairs of pre- and post-etodolac-treatment endometrial cytological samples were collected to review changes in the cytological features. Results: In the COX-2-positive patients, nuclear atypia was slightly decreased in 3 of the 16 cases, while the mitotic index was decreased in all cases. Cellular overlapping and tumor cell cluster outlines were somewhat affected in 6 and 8 cases, respectively. Nuclear/cytoplasmic ratio, anisokaryosis and hyperchromasia were also reduced in 6, 4, and 2 cases, respectively; however, tumor diathesis and nucleoli features were unchanged. In contrast, endometrial cytological features did not appear to be affected in the 5 COX-2-negative patients. Conclusions: We conclude that the antitumor effects observed in endometrial cancer tissues following oral administration of etodolac are reflected in and can be easily assessed by evaluating endometrial cytological features. Copyright (c) 2012 S. Karger AG, Basel

書籍等出版物

 11

講演・口頭発表等

 29

担当経験のある科目(授業)

 3

教育内容・方法の工夫(授業評価等を含む)

 1
  • 件名
    -
    概要
    学生が興味を持てる様に写真や図表を入れる。

作成した教科書、教材、参考書

 2
  • 件名
    臨床細胞病理学実習書
    開始年月日
    2000
    概要
    臨床細胞病理学実習書
  • 件名
    国家試験用写真問題集、国家試験用問題集
    開始年月日
    2006
    概要
    国家試験対策問題集

その他教育活動上特記すべき事項

 1
  • 件名
    -
    概要
    医学部、医療科学部1年生のアセンブリ班に対して発表演奏会を行なった。