研究者業績

井野 敬子

イノ ケイコ  (INO KEIKO)

基本情報

所属
武蔵野大学 認知行動療法研究所 (客員研究員)
名古屋市立大学 大学院医学研究科 精神・認知・行動医学分野 客員講師

J-GLOBAL ID
201801000097843021
researchmap会員ID
B000333255

トラウマのせいで時間が止まった患者さま、幼い頃の家庭環境が複雑で後遺症としての精神症状をお持ちの患者さまに貢献できるような研究を進めていきたいと思い、PTSDの認知行動療法(持続エクスポージャー療法)の治療研究と実装研究を専門としています。心理療法を受けたくても得られない患者さまに治療を届けることがライフワークの一つです。
 
また摂食障害の治療リソースの不足を目の当たりにし、医療体制が改善しないといけないという問題意識を持ち、摂食障害治療支援センター設置運営事業に携わるようになりました。 


論文

 34
  • Natsuki Ueda, Mingming Lin, Mariko Itoh, Hiroaki Hori, Zui Narita, Madoka Niwa, Keiko Ino, Megumi Narita, Wakako Nakano, Risa Imai, Mie Matsui, Toshiko Kamo, Yoshiharu Kim
    European journal of psychotraumatology 16(1) 2543079-2543079 2025年12月  
    Background/objective: Posttraumatic stress disorder (PTSD) is known to be associated with deficits in working memory (WM). However, findings regarding the relationship of PTSD with non-emotional WM have not necessarily been uniform. This study aimed to clarify the relationship between PTSD and non-emotional WM using the N-back task, a well-established WM task.Method: A total of 111 women with PTSD and 120 healthy control women without trauma were enrolled. Most of the patients developed PTSD after experiencing interpersonal violence. Participants completed 0-back and 2-back tasks using non-emotional stimuli (number), as well as a standardised neuropsychological test battery and self-report questionnaires for PTSD and depression symptoms.Results: The PTSD group showed significantly less accuracy in the 2-back task than the control group, while no significant difference was observed in the accuracy of the 0-back task. The PTSD group showed significantly prolonged reaction time compared to controls in both the 0-back and 2-back tasks. The prolonged reaction time in the 2-back task was significantly correlated with more severe overall symptoms and avoidance symptoms in the PTSD group after controlling for age.Conclusion: Individuals with PTSD exhibited reduced WM capacity. Drawing on a relatively large civilian sample, this study contributes to the accumulating evidence of such deficits. Notably, the observed association between WM dysfunction and avoidance symptoms suggests a symptom-specific cognitive profile in PTSD.
  • 小川 眞太朗, 堀 弘明, 丹羽 まどか, 伊藤 真利子, 林 明明, 吉田 冬子, 井野 敬子, 河西 ひとみ, 成田 恵, 中野 稚子, 今井 理紗, 松井 三枝, 加茂 登志子, 功刀 浩, 服部 功太郎, 金 吉晴
    国立精神・神経医療研究センター精神保健研究所年報 (38) 200-200 2025年9月  
  • Sayo Hamatani, Kazuki Matsumoto, Gerhard Andersson, Yasuhiro Sato, Shin Fukudo, Yusuke Sudo, Yoshiyuki Hirano, Keiko Ino, Tomoaki Ishibashi, Yukiko Tomioka, Hidehiro Umehara, Shusuke Numata, Masayuki Nakamura, Ryoko Otani, Ryoichi Sakuta, Atsushi Sekiguchi, Hirotaka Kosaka, Yoshifumi Mizuno, Rio Kamashita, Tokiko Yoshida, Kanae Matsuura, Shinji Tomari, Misako Funaba, Natsuki Sasaki, Haruka Sako, Shoko Shimada, Takeshi Inoue
    JAMA Network Open 8(8) e2525165-e2525165 2025年8月5日  
    Importance Despite the rising prevalence of bulimia nervosa and the associated risks of chronicity and severe physical and psychological morbidity, access to effective treatment remains poor. The effectiveness and acceptability of internet-based cognitive behavior therapy (ICBT) for women with bulimia nervosa in clinical settings in East Asia remain unclear. Objective To determine the effectiveness and acceptability of a guided ICBT program to treat women with bulimia nervosa in Japan. Design, Setting, and Participants This randomized clinical trial was conducted at 7 university hospitals in Japan between August 2022 and October 2024. This study enrolled female participants aged 13 to 65 years whose symptoms met the Diagnostic and Statistical Manual of Mental Disorders (Fifth Edition) criteria for bulimia nervosa, had a body mass index (BMI) of 17.5 or greater, had internet access, and had no history of practicing CBT-related techniques within the past 2 years. Interventions Both the control and intervention groups received usual care. The intervention consisted of ICBT with additional guidance from a therapist. The therapy program was tailored to Japanese culture and grounded in a specific cognitive behavior model, and it was performed over a 12-week period. Main Outcomes and Measures Severity of bulimia nervosa, measured by the weekly combined frequency of episodes involving binge eating and compensatory behaviors, was assessed by a blinded, independent rating team at baseline and at the 12-week intervention end point. Intention-to-treat analyses were conducted using a linear mixed model with effect sizes calculated using Cohen d. Results A total of 61 women met the eligibility criteria and were randomized to the intervention group (n = 31) or the control group (n = 30). Participants were predominantly young (mean [SD] age, 27.8 [9.0] years), had normal weight (mean [SD] BMI, 21.1 [3.6]), and had a mean (SD) duration of illness of 9.3 (8.8) years; half (31 [50.8%]) were employed. Intent-to-treat analysis revealed that guided ICBT significantly reduced the weekly combined frequency of episodes involving binge eating and compensatory behaviors (by an adjusted mean difference of 9.84 episodes [95% CI, 2.49-17.18 episodes], P = .01; Cohen d = 0.73 [95% CI, 0.21-1.26]). Sensitivity analyses supported these findings. Conclusions and Relevance In this randomized clinical trial, the intervention group experienced a significant decrease in bulimia symptoms compared with the control group, supporting the effectiveness and acceptability of the therapist-guided ICBT program. These findings suggest that integration of therapist-guided ICBT in usual care has the potential to improve accessibility to efficacious treatment options for women with bulimia nervosa. Trial Registration UMIN Clinical Trials Registry Identifier: UMIN00048732
  • Yuta Yamauchi, Keiko Ino, Masanori Sakaguchi, Keiichi Zempo
    ACM Transactions on Computing for Healthcare 2025年3月19日  査読有り
  • Yuko Toshishige, Michi Nakayama, Mie Sakai, Keiko Ino, Yoshihiko Harada, Tatsuo Akechi
    Psychiatry and Clinical Neurosciences Reports 4(1) 2025年3月2日  
    Abstract Background Subthreshold post‐traumatic stress disorder (PTSD) is associated with nearly the same impairment level as full PTSD. However, the standard treatment for subthreshold PTSD remains unclear. Furthermore, no consensus has been reached on the best way to address grief following the improvement of PTSD symptoms. Case Presentation A single Japanese woman in her 50s experienced sudden fear and insomnia after her only son committed suicide. She visited our hospital 6 months after the death and was diagnosed with depression and subthreshold PTSD. Pharmacotherapy slightly improved her depression and insomnia, but no improvement was observed in her PTSD symptoms, therefore she underwent 13 prolonged exposure (PE) sessions, including grief care in the final two sessions. Through imaginal exposure, she was able to feel her anger toward her deceased son and the feelings he had at the time of the suicide for the first time. Furthermore, as she processed her feelings about her son's suicide, her perception changed, which substantially alleviated her depressive and PTSD symptoms. After her PTSD symptoms improved, she felt sadness for his loss. Consequently, the grieving process was facilitated. Conclusion PE incorporating brief grief care may be effective for the bereaved with suicide‐related PTSD symptoms.

MISC

 19

担当経験のある科目(授業)

 2

所属学協会

 9

共同研究・競争的資金等の研究課題

 8