TANAMOTO KEN'ICHI

(棚元憲一)

Profile Information

Affiliation: Faculty of Pharmacy, Department of Pharmaceutical Sciences, Musashino University

Degree: 学士(東京大学)
博士(東京大学)

J-GLOBAL ID: 200901064998242955
researchmap Member ID: 0000041232

Research History

Apr, 2009 - Present

of Pharmaceutical Sciences, Graduate School, Musashino University
Apr, 2009 - Present

Faculty of Pharmacy, Department of Pharmaceutical Sciences, Musashino University
Apr, 2009 - Present

of Pharmaceutical Sciences, Graduate School, Musashino University
Apr, 1999

Manager(Dean)
Apr, 1990

Head

Education

- Mar, 1972

Faculty of Pharmaceutical Science, The University of Tokyo

Committee Memberships

Jun, 1999 - Present

理事, 日本食品衛生学会
Jun, 2011 - Jun, 2013

副会長, 日本食品衛生学会
Jun, 2002 - Jun, 2013

常任理事, 日本食品衛生学会
Apr, 1996 - Mar, 2013

世話人, 日本エンドトキシン研究会
Apr, 2009 - Mar, 2012

編集委員, 日本薬学会

Awards

Apr, 1980

日本細菌学会黒屋奨学賞

Papers

NF-kappa B activation via MyD88-dependent Toll-like receptor signaling is inhibited by trichothecene mycotoxin deoxynivalenol

Kei-ichi Sugiyama, Masashi Muroi, Mawo Kinoshita, Osamu Hamada, Yuji Minai, Yoshiko Sugita-Konishi, Yoichi Kamata, Ken-ichi Tanamoto

JOURNAL OF TOXICOLOGICAL SCIENCES, 41(2) 273-279, Apr, 2016 Peer-reviewed
Zinc- and oxidative property-dependent degradation of pro-caspase-1 and NLRP3 by ziram in mouse macrophages

Masashi Muroi, Ken-ichi Tanamoto

TOXICOLOGY LETTERS, 235(3) 199-205, Jun, 2015 Peer-reviewed
Toll-Like Receptors Required for Dermatophagoides farinae to Activate NF-kappa B

Takaaki Kitajima, Masashi Muroi, Naomi Yamashita, Ken-ichi Tanamoto

BIOLOGICAL & PHARMACEUTICAL BULLETIN, 37(1) 74-80, Jan, 2014 Peer-reviewed
Role of Toll-Like Receptor 4 in Mediating Multiorgan Dysfunction in Mice With Acetaminophen Induced Acute Liver Failure

Naina Shah, Montserrat Montes de Oca, Maria Jover-Cobos, Ken-ichi Tanamoto, Masashi Muroi, Kei-ichi Sugiyama, Nathan A. Davies, Rajeshwar P. Mookerjee, Dipok Kumar Dhar, Rajiv Jalan

LIVER TRANSPLANTATION, 19(7) 751-761, Jul, 2013 Peer-reviewed
Lipid IVa incompletely activates MyD88-independent Toll-like receptor 4 signaling in mouse macrophage cell lines

Norihiko Ogura, Masashi Muroi, Yuka Sugiura, Ken-ichi Tanamoto

PATHOGENS AND DISEASE, 67(3) 199-205, Apr, 2013 Peer-reviewed

Misc.

172

3H-endotoxin の体内分布に及ぼす大量肝切除の影響

白井睦訓, 西岡幹夫, 志賀淳治, 森亘, 吉村吾志夫, 福田一郎, 金ヶ崎士朗

エンドトキシン臨床研究の新しい展開, 125-130, 1987
Structure-activity relationship of lipid A: Comparison of biological activity of natural and synthetic lipid A's with different fatty acid compositions.

Kanagasaki S, K. Tanamoto, T.Yasuda, J.Y.Homma, M.Matsuura, Y.Kumazawa, T.Shiba, S.Kusumoto

J.Biochem., 99 1203-1210, 1986
Structural requirements of lipid A responsible for the functions: A study with chemically synthesized lipid A and its analogues.

Homma J.Y, M.Matsuura, S.Kanegasaki, Y.Kojima, Y.Kumazawa, A.Yamamoto, K. Tanamoto, T.Yasuda, M.Imoto, H.Yoshimura, S.Kusumoto, T.Shiba

J.Biochem., 98 395-406, 1985
Mitogenic activities of chemically synthesized lipid A analogues and suppression of mitogenicity of lipid A.

Tanamoto K, C.Galanos, O.Luderitz, S.Kusumoto, T.Shiba

Infect. Immun., 44 427-433, 1984
Lipopolysaccharides: Structural principles and biologic activities.

Luderitz O, C.Galanos, G.R.Mckenzie, H.Brade, U.Zahringer, E.Th.Rietschel, S.Kusumoto, T.Shiba

Rev. Infect. Dis., 6 428-432, 1984
Endotoxic properties of chemically synthesized lipid A part structures. Comparison of synthetic lipid A precursor and synthetic analogues with biosynthetic lipid A precursor and free lipid A.

Galanos C, V.Lehman, O.Luderitz, E.Th Rietschel, O.Westphal, H.Brade, M.Freudenberg, T.Hansen-Hagge, G.McKenzie, U.Schade, W.Strittmatter, K. Tanamoto, U.Zahringer, M.Imoto, M.Yamamoto, S.Kusumoto, T.Shiba

Eur. J. Biochem., 140 221-227, 1984
Biological activities of synthetic lipid Aanalogues: Pyrogenisity, lethal toxicity, anticomplementary activity and induction of gelation of Limulus Amoebocyte lysate.

Tanamoto K, U.Zahringer, G.R.McKenzie, C.Galanos, E.Th.Rietschel, O.Luderitz, S.Kusumoto, T.Shiba

Infect.Immun., 44 427-433, 1984
Biological activities of analogues of lipid A based chemically on the revised structural model. Comparison of mediator-inducing immunomodulating and endotoxic activities.

KanegasAki S, Y.Kojima, M.Matsuura, J.Y.Homma, A.Yamamoto, Y.Kumazawa, K. Tanamoto, T.Yasuda, T.Tsumita, M.Imoto, H.Yoshimura, Y.Shimamoto, S.Kusumoto, T.Shiba

Eur. J. Biochem., 143 237-242, 1984
Structural principle of lipopolysaccharides and biological properties of synthetic partial structures

Luderitz O, C.Galanos, O.Westphal, U.Zahringer, E.Th.Rietschel, S.Kusumoto, T.Shiba

Am.Chem.Soc.. Symp.Ser., 231 3-17, 1983
Prostaglandins increase sensitivity of alveolar macrophages towards lipopolysaccharide(endotoxin).

Tanamoto K, U.Schade, E.Th.Rietsche

Immunobiol., 165 363, 1983
Essential regions of the lipopolysaccharide of Pseudomonas aeruginosa responsible for pyrogenicity and activation of t he proclotting enzyme of Horseshoe clabs.

Tanamoto K, J.Y.Homma

J.Biochem., 91 741-746, 1982
Die Rolle der Prostaglandine bei Schwersten Zustanden.

Rietschel E.Th, K. Tanamoto, U.Shade

Munch. Med. Wschr., 124 55-60, 1982
緑膿菌内毒素蛋白部分の構造と生物活性

阿部千代治

日本細菌学会雑誌, 36 565-571, 1981
Regions of the lipopolysaccharide of pseudomonas aeruginosa seencial for antitumor and interferon-inducing activities.

Tanamoto K, C.Abe, J.Y.Homma, Y.Kojima

Eur.J.Biochem., 97 623-629, 1979
Differences of chemical structures of Pseudomonas aeruginosa lipopolysaccharide essential for adjuvamticity and antitumor and interferon-inducing activities.

Cho Y, K. Tanamoto, J.Y.Homma, Y.Kojima

FEBS Lett., 105 120-122, 1979
Effectiveness of immunization with single and multi component vaccines prepared from a common antigen(OEP),protease and elastase toxoids of Pseudomonas aeruginosa on protection against hemorrhagic Pneumonia in mink due to P.aeruginosa.

Homma J.Y, C.Abe, K. Tanamoto, Y.Hirao, K.Morihara, H.Tsuzuki, R.Yanagawa, E.Honda, Y.Aoi, Y.Fujimoto, M.Goryo, N.Imazeki, H.noda, A.Goda, S.Takeuchi, T.Ishihara

Japan J. Exp. Med., 48 111-133, 1978
A compound possessing antitumor and interferon -inducing activities.

Tanamoto K, C.Abe, J.Y.Homma, K.Kuretani, A.Hoshi, Y.Kojima

J.Biochem., 83 711-718, 1978
Infection protective property of the common antigen(OEP) of Pseudomonas aeruginosa and its chemical composition.

Abe C, K. Tanamoto, J.Y.Homma

Japan. J. Exp. Med., 47 393-402, 1977
Effects of the common antigen(OEP) and toxoids of protease and elastase from Pseudomonas aeruginosa on protection against hemorrhagic Pneumonia in mink.

Honda E, J.Y.Homma, C.Abe, K. Tanamoto, H.Noda, R.Yanagawa

Zbl. Bact. Hyg., 237 297-309, 1977
The biological properties of endotoxin of Pseudomonas aeruginosa

Homma J.Y, C.Abe, K.Okada, Y.Hirao

Animal, Plant and Microbial Toxins, 1 499-508, 1976
Effect of the common antigen vaccination to protect mink from challenge exposure with Pseudomonas aeruginosa

Shimizu T, J.Y.Homma, C.Abe, K. Tanamoto, Y.Aoyama, Y.Fujimoto, H.Noda, I.Takashima, E.Honda, S.Minamide

Am.J.Vet.Res., 37 1441-1444, 1976
Chemical and biological properties of the protein moiety of endotoxin of Pseudomonas aeruginosa

阿部千代治, 本間遜

蛋白質・核酸・酵素, 283-296, 1976

Books and Other Publications

微生物試験法Q&A 現場の困った！に答える誌上セミナー

（株）じほう, 2016
エンドトキシン試験法

（株）じほう, 2016
TRAF6を介したシグナル伝達とシグナル抑制に必要なIRAK-1の構造領域

室井正志, 棚元憲一 (Role: Joint author)

医学図書出版, 2016
微生物試験法Q&A 現場の困ったに答える誌上セミナー

（株）じほう, 2014
エンドトキシン試験法

じほう, 2013

Presentations

エンドトキシン構造認識における生物種差とエンドトキシン試験法

Jul, 2011 Invited
生物によるエンドトキシン構造の認識

エンドトキシン試験法セミナー, Feb, 2010 Invited

招待講演（2002年以降)棚元憲一
食品添加物行政研究に携わって－安全性確保に向けての取り組み－

食品添加物技術フォーラム, Aug, 2009 Invited

招待講演（2002年以降)棚元憲一
食品添加物公定書の改訂

日本薬学会レギュラトリーサイエンス部会、食品安全フォーラム, Nov, 2007 Invited

招待講演（2002年以降)棚元憲一
食品添加物の現状と問題点

食品開発展２００７記念セミナー, Nov, 2007 Invited

招待講演（2002年以降)棚元憲一

Professional Memberships

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TANAMOTO KEN&#039;ICHI

Profile Information

Research History

Education

Committee Memberships

Awards

Papers

Misc.

Books and Other Publications

Presentations

Professional Memberships

TANAMOTO KEN'ICHI