研究者業績

幸田光復

コウダコウフク (Kohfuku Kohda)

基本情報

所属: 武蔵野大学薬学研究所教授

学位: 薬学博士
薬学修士

J-GLOBAL ID: 200901008223441849
researchmap会員ID: 1000055199

研究分野

1

ナノテク・材料 / 生体化学 /

学歴

4

受賞

1

1984年

佐藤記念国内賞

MISC

238

Studies on Chemical Carcinogens. XVII. Structure of Carcinogenic 4-Hydroxyminoquinoline 1-Oxide Derivatives

KAWAZOE Y, OGAWA O, HUANG G-F

┣DBTetrahedron(/)-┫DB 36(20/21) 2933-2938 1980年
Studies on Chemical Carcinogens. XVII. Structure of Carcinogenic 4-Hydroxyminoquinoline 1-Oxide Derivatives

┣DBTetrahedron(/)-┫DB 36(20/21) 2933-2938 1980年
Carcinogenicity and Mutagenicity of 4-Nitropyridine 1-Oxide Derivatives

┣DBGann(/)-┫DB 70 799-806 1979年
Interferon Induction by Mismatched Analogues of Polyinsinic Acid. Polycytidilic Acid[(I_x, U)_n. (C)_n]

┣DBNucleic Acid Research(/)-┫DB 7(7) 2003-2014 1979年
5-Substituted Uracil Arabinosides as Potent Antiviral Agents

┣DBJ. Med. Chem.(/)-┫DB 22(3) 316-319 1979年
Synthesis and Antiviral Activities of New 5-Substituted Pyrimidine Nucleoside Analogs

North Holland Biolmedical Press 59-85 1979年
Comparative Study of Potency and Selectivity of Anti-Herpes Compounds

Proceedings of the FEBS Symposium on ”Antimetabolites in Biochemistry, Biology and Medicine”, Pergamon Press 275-285 1979年
Carcinogenicity and Mutagenicity of 4-Nitropyridine 1-Oxide Derivatives

┣DBGann(/)-┫DB 70 799-806 1979年
Interferon Induction by Mismatched Analogues of Polyinsinic Acid. Polycytidilic Acid[(I_x, U)_n. (C)_n]

┣DBNucleic Acid Research(/)-┫DB 7(7) 2003-2014 1979年
5-Substituted Uracil Arabinosides as Potent Antiviral Agents

┣DBJ. Med. Chem.(/)-┫DB 22(3) 316-319 1979年
Synthesis and Antiviral Activities of New 5-Substituted Pyrimidine Nucleoside Analogs

North Holland Biolmedical Press 59-85 1979年
Comparative Study of Potency and Selectivity of Anti-Herpes Compounds

Proceedings of the FEBS Symposium on ”Antimetabolites in Biochemistry, Biology and Medicine”, Pergamon Press 275-285 1979年
5-Nitro-2'-Deoxyuridine 5'-Monophosphate is A Potent Irreversible Inhibitor of ┣DBLactobacillus Caesi(/)-┫DB Thymidilate Synthetase

┣DBBiochem. Biophys. Res. Com.(/)-┫DB 84(4) 1054-1059 1978年
Nitration of Cytosine, 1-Methylcytosine and 2'-Deoxycytidine 5'-Monophosphate by Nitronium Testrafluoroborate in Sulfolane. Preparation of 5-Nitro-I'-Deoxycytidine

┣DBJ. Carbohydrates, Nucleosides, Nucleotides.(/)-┫DB 5 317-327 1978年
5-Nitro-2'-Deoxyuridine and 5-Nitro-2'-Deoxyuridine 5'-Monophosphate : Antiviral Activity and Inhibition of Thymidilate Synthetase in Vivo

┣DBMol. Pharmacol.(/)-┫DB 14 422-430 1978年
5-Nitro-2'-Deoxyuridine 5'-Monophosphate is A Potent Irreversible Inhibitor of ┣DBLactobacillus Caesi(/)-┫DB Thymidilate Synthetase

┣DBBiochem. Biophys. Res. Com.(/)-┫DB 84(4) 1054-1059 1978年
Nitration of Cytosine, 1-Methylcytosine and 2'-Deoxycytidine 5'-Monophosphate by Nitronium Testrafluoroborate in Sulfolane. Preparation of 5-Nitro-I'-Deoxycytidine

┣DBJ. Carbohydrates, Nucleosides, Nucleotides.(/)-┫DB 5 317-327 1978年
5-Nitro-2'-Deoxyuridine and 5-Nitro-2'-Deoxyuridine 5'-Monophosphate : Antiviral Activity and Inhibition of Thymidilate Synthetase in Vivo

┣DBMol. Pharmacol.(/)-┫DB 14 422-430 1978年
Nitration of Pyrimidine Bases and Nucleotides by Nitronium Tetrafluoroborate. Synthesis of 5-Nitro-2'-Deoxyuridine

┣DBJ. Org. Chem.(/)-┫DB 42(24) 3821-3824 1977年
Biologic Activities of Poly (2-Azaadenylic Acid) and Poly (2-Azainosinic Acid) Erik De Clercq, Guang-Fu Huang, Paul F. Torrence, Toshikazu Fukui, Nobuko Kakiuchi and Morio Ikehara

┣DBNucleic Acids Research(/)-┫DB 4(10) 3643-3653 1977年
Nitration of Pyrimidine Bases and Nucleotides by Nitronium Tetrafluoroborate. Synthesis of 5-Nitro-2'-Deoxyuridine

┣DBJ. Org. Chem.(/)-┫DB 42(24) 3821-3824 1977年
Biologic Activities of Poly (2-Azaadenylic Acid) and Poly (2-Azainosinic Acid) Erik De Clercq, Guang-Fu Huang, Paul F. Torrence, Toshikazu Fukui, Nobuko Kakiuchi and Morio Ikehara

┣DBNucleic Acids Research(/)-┫DB 4(10) 3643-3653 1977年
Mutagenicity of K-region Epoxides of Polycyclic Aromatic Compounds : Structure-Activity Relationship

┣DBMutation Res.(/)-┫DB 37 187-192 1976年
Mutagenicity of K-region Epoxides of Polycyclic Aromatic Compounds : Structure-Activity Relationship

┣DBMutation Res.(/)-┫DB 37 187-192 1976年
Chemical Structure of QAII, One of the Covalently Bound Adducts of Carcinogenic 4-Nitroquinoline 1-Oxide with Nucleic Acid Bases of Cellular Nucleic Acids

川添豊, 荒木美佐子, 岡本敏彦, 多田満彦, 多田万里子

┣DBChem. Pharm. Bull.(/)-┫DB 23(11) 3041-3043 1975年
Studies on Chemical Alterations of Nucleic Acids and Their Components. IX. Synthesis and Reaction of 1-Aminoadenosine and Related Compounds

┣DBTetrahedron(/)-┫DB 31 1363-1367 1975年
Chemical Structure of QAII, One of the Covalently Bound Adducts of Carcinogenic 4-Nitroquinoline 1-Oxide with Nucleic Acid Bases of Cellular Nucleic Acids

YUTAKA KAWAZOE, MISAKO ARAKI, GUANGFU HUANG, TOSHIHIKO OKAMOTO, MITSUHIKO TADA, MARIKO TADA

┣DBChem. Pharm. Bull.(/)-┫DB 23(11) 3041-3043 1975年
Studies on Chemical Alterations of Nucleic Acids and Their Components. IX. Synthesis and Reaction of 1-Aminoadenosine and Related Compounds

┣DBTetrahedron(/)-┫DB 31 1363-1367 1975年
Studies on Chemical Alterations of Nucleic Acids and Their Components. VIII. Alkalaine Rearrangement of 1-Aminoadenosine to 5-Amino-1-β-D-ribofuranosyl-4-(1,2,4-triazol-3-yl) imidazole

黄光復, 岡本敏彦, 前田満和, 川添豊

┣DBChem. Pharm. Bull.(/)-┫DB Japan 22(8) 1938-1939 1974年
Studies on Chemical Alterations of Nucleic Acids and Their Components. VIII. Alkalaine Rearrangement of 1-Aminoadenosine to 5-Amino-1-β-D-ribofuranosyl-4-(1,2,4-triazol-3-yl) imidazole

GUANGFU HUANG, TOSHIHIKO OKAMOTO, MITSUAKI MAEDA, YUTAKA KAWAZOE

┣DBChem. Pharm. Bull.(/)-┫DB Japan 22(8) 1938-1939 1974年
Studies on Chemical Alterations of Nucleic Acid and Their Components. VI. N-Amination of Some Nucleic Acid Bases Containing Basic Nitrogen with Hydroxylamine-O-Esters

┣DBTetrahedron Letters(/)-┫DB 4541-4544 1973年
Studies on Chemical Alterations of Nucleic Acid and Their Components. VI. N-Amination of Some Nucleic Acid Bases Containing Basic Nitrogen with Hydroxylamine-O-Esters

┣DBTetrahedron Letters(/)-┫DB 4541-4544 1973年
Chemical Aspects of Carcinogenesis by 4-Nitroquinoline 1-Oxide

University of Tokyo Press 1-13 1972年
Direct C-Amination of Guanine with Hydroxylamine-O-Sulfonic Acid. Simplest Model Reaction Possibly Involved in DNA Damage Leading to Carcinogenesis by N-Arylhydroxylamines

┣DBChem. Pharm. Bull.(/)-┫DB 20 2073-2074 1972年
Chemical Binding of Carcinogenic 4-Nitroquinoline 1-Oxide Derivatives with DNA ┣DBin(/)-┫DB ┣DBvivo(/)-┫DB and ┣DBin(/)-┫DB ┣DBvitro(/)-┫DB

┣DBGANN(/)-┫DB 63 161-166 1972年
Chemical Aspects of Carcinogenesis by 4-Nitroquinoline 1-Oxide

University of Tokyo Press 1-13 1972年
Direct C-Amination of Guanine with Hydroxylamine-O-Sulfonic Acid. Simplest Model Reaction Possibly Involved in DNA Damage Leading to Carcinogenesis by N-Arylhydroxylamines

┣DBChem. Pharm. Bull.(/)-┫DB 20 2073-2074 1972年
Chemical Binding of Carcinogenic 4-Nitroquinoline 1-Oxide Derivatives with DNA ┣DBin(/)-┫DB ┣DBvivo(/)-┫DB and ┣DBin(/)-┫DB ┣DBvitro(/)-┫DB

┣DBGANN(/)-┫DB 63 161-166 1972年

書籍等出版物

14

Miscoding potential of the ┣DBN(/)-┫DB²-ethyl-2'-deoxyguanosine DNA adduct by the exonuclease-free Klenow fragment of ┣DBEscherichia coli(/)-┫DB DNA polymerase (]G0001[)(共著)

┣DBBiochemistry(/)-┫DB 2001年
Miscoding potential of the ┣DBN(/)-┫DB²-ethyl-2'-deoxyguanosine DNA adduct by the exonuclease-free Klenow fragment of ┣DBEscherichia coli(/)-┫DB DNA polymerase (]G0001[)(共著)

┣DBBiochemistry(/)-┫DB 2001年
Syntheses and properties of 1-methyl-3-phenylaminobenzimidazolium salts, models of DNA adducts of N7-arylaminodeoxyguanosinium salt.(共著)

┣DBChem. Res. Toxicol.(/)-┫DB 2000年
┣DBO(/)-┫DB⁶-(Fluorobenzyl)guanine and chloroethylnitrosourea in xenografted rat brain tumor in vivo.(共著)

┣DBActa Oncol.(/)-┫DB 2000年
Reactions of a series of ┣DBN(/)-┫DB-aminobenzimidazoles and ┣DBN(/)-┫DB-aminobenzimidazolium salts with 2, 4-pentanedione.(共著)

┣DBBioorg. Med. Chem.(/)-┫DB 2000年

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所属学協会

3

共同研究・競争的資金等の研究課題

2

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