研究者業績

櫻井 建成

サクライ タツナリ  (Tatsunari Sakurai)

基本情報

所属
武蔵野大学 工学部 数理工学科 教授
学位
博士(工学)(1998年3月 山口大学)

研究者番号
60353322
J-GLOBAL ID
200901084069851832
researchmap会員ID
1000362262

研究キーワード

 2

論文

 35
  • Hiroyuki Kitahata, Junji Taguchi, Masaharu Nagayama, Tatsunari Sakurai, Yumihiko Ikura, Atsushi Osa, Yutaka Sumino, Masanobu Tanaka, Etsuro Yokoyama, Hidetoshi Miike
    Journal of Physical Chemistry A 126(41) 7557 2022年10月20日  
    I n our original manuscript, the parameter values were incorrectly described in the caption of Figure 5. The parameters should be “au/a = 1 and av/a = 0.1” instead of “αu/α = αv/α = 0.1”. In addition, “au = av = 3.7” was incorrect, and it should be “au = 37 and av = 3.7”. The errors are typographical, and thus, these corrections do not affect the conclusions of this work.
  • Chika Okimura, Misaki Iwanaga, Tatsunari Sakurai, Tasuku Ueno, Yasuteru Urano, Yoshiaki Iwadate
    Proceedings of the National Academy of Sciences of the United States of America 119(18) e2119903119 2022年5月3日  
    Collective cell migration is seen in many developmental and pathological processes, such as morphogenesis, wound closure, and cancer metastasis. When a fish scale is detached and adhered to a substrate, epithelial keratocyte sheets crawl out from it, building a semicircular pattern. All the keratocytes at the leading edge of the sheet have a single lamellipodium, and are interconnected with each other via actomyosin cables. The leading edge of the sheet becomes gradually longer as it crawls out from the scale, regardless of the cell-to-cell connections. In this study, we found leading-edge elongation to be realized by the interruption of follower cells into the leading edge. The follower cell and the two adjacent leader cells are first connected by newly emerging actomyosin cables. Then, the contractile forces along the cables bring the follower cell forward to make it a leader cell. Finally, the original cables between the two leader cells are stretched to tear by the interruption and the lamellipodium extension from the new leader cell. This unique actomyosin-cable reconnection between a follower cell and adjacent leaders offers insights into the mechanisms of collective cell migration.
  • Yuki Koyano, Tatsunari Sakurai, Hiroyuki Kitahata
    PHYSICAL REVIEW E 96(3) 2017年9月  査読有り
  • Tatsunari Sakurai, Tohru Tsujikawa, Daisuke Umeno
    Complexity and Synergetics 227-237 2017年1月1日  
    A concentric pulse by motile cells of Escherichia coli (E. coli) propagates and the cells aggregate to form self-organized patterns.We summarize experimental and numerical results on the self-organized pattern formation of E. coli to elucidate some aspects of its mechanism. Our presentation includes experiments on E. coli patterns, as well as numerical simulations on the basis of a reaction-diffusionchemotaxis model.We find good agreement for one-dimensional propagating fronts in observation and simulation. However, corresponding results for two-dimensional circular bacterial clusters have still not been obtained.
  • Masanobu Horie, Tatsunari Sakurai, Hiroyuki Kitahata
    Physical Review E 93(1) 2016年1月20日  査読有り
    We investigated the phase-response curve of a coupled system of density oscillators with an analytical approach. The behaviors of two-, three-, and four-coupled systems seen in the experiments were reproduced by the model considering the phase-response curve. Especially in a four-coupled system, the clustering state and its incidence rate as functions of the coupling strength are well reproduced with this approach. Moreover, we confirmed that the shape of the phase-response curve we obtained analytically was close to that observed in the experiment where a perturbation is added to a single-density oscillator. We expect that this approach to obtaining the phase-response curve is general in the sense that it could be applied to coupled systems of other oscillators such as electrical-circuit oscillators, metronomes, and so on.

MISC

 20

共同研究・競争的資金等の研究課題

 22