ENOMOTO TAKEMI

(榎本武美)

Profile Information

Affiliation: Professor, Musashino University

Degree: 学士(東京大学)
修士(東京大学)
博士(東京大学)

J-GLOBAL ID: 200901056088076439
researchmap Member ID: 1000183964

Research Interests

Research Areas

Life sciences / Molecular biology /

Research History

Education

- 1981

アルバートアインシュタイン医科大学
- 1975

The University of Tokyo
- 1975

Graduate School, Division of Pharmaceutical Sciences, The University of Tokyo
- 1972

The University of Tokyo
- 1972

Graduate School, Division of Pharmaceutical Sciences, The University of Tokyo

Misc.

267

WRNIP1 accumulates at laser light irradiated sites rapidly via its ubiquitin-binding zinc finger domain and independently from its ATPase domain

Hironoshin Nomura, Akari Yoshimura, Takato Edo, Shin-ichiro Kanno, Syusuke Tada, Masayuki Seki, Akira Yasui, Takemi Enomoto

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 417(4) 1145-1150, Jan, 2012
Nucleosome surface containing nucleosomal DNA entry/exit site regulates H3-K36me3 via association with RNA polymerase II and Set2

Hirohito Endo, Yu Nakabayashi, Satoshi Kawashima, Takemi Enomoto, Masayuki Seki, Masami Horikoshi

GENES TO CELLS, 17(1) 65-81, Jan, 2012
Embryonic Lethality in Mice Lacking Mismatch-Specific Thymine DNA Glycosylase Is Partially Prevented by DOPS, a Precursor of Noradrenaline

Yusuke Saito, Tetsuya Ono, Naoki Takeda, Takehiko Nohmi, Masayuki Seki, Takemi Enomoto, Tetsuo Noda, Yoshihiko Uehara

TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE, 226(1) 75-83, Jan, 2012
Roles of histone chaperone CIA/Asf1 in nascent DNA elongation during nucleosome replication

Katsuyuki Ishikawa, Tatsuya Ohsumi, Shusuke Tada, Ryo Natsume, Lena Rani Kundu, Naohito Nozaki, Toshiya Senda, Takemi Enomoto, Masami Horikoshi, Masayuki Seki

GENES TO CELLS, 16(10) 1050-1062, Oct, 2011
Roles of histone chaperone CIA/Asf1 in nascent DNA elongation during nucleosome replication

Katsuyuki Ishikawa, Tatsuya Ohsumi, Shusuke Tada, Ryo Natsume, Lena Rani Kundu, Naohito Nozaki, Toshiya Senda, Takemi Enomoto, Masami Horikoshi, Masayuki Seki

GENES TO CELLS, 16(10) 1050-1062, Oct, 2011

Books and Other Publications

生物系薬学IV 演習編

東京化学同人, Jun, 2011
生物系薬学II 第２版

東京化学同人, Dec, 2010
生物系薬学II 日本薬学会編

東京化学同人

200500
Molecular mechanism of Werner's syndrome edited by Michel Lebel Kluwer Academic

Plenum Publishers, New York,

200400
廣川タンパク質化学第４巻酵素福井哲也、伊藤正樹編

廣川書店

200300

Presentations

601

DNA二本鎖切断修復におけるRecQL4の機能の解析

日本薬学会第126年会仙台市, 2006
BLM の DNA 二重鎖切断部位への迅速な集積

日本薬学会第126年会仙台市, 2006
Systematic genetical analyses for one of the essential subunits of DNA polymerase delta (Pold) in Saccharomyces cerevisiae.

2006
Sgs1-Top3 complex, contributes to sister chromatid cohesion in yeast Saccharomyces cerevisiae.

2006
DNA複製開始制御機構におけるCdt1の生化学的機能解析

第3回東北大学バイオサイエンスシンポジウム仙台国際センター（仙台市）, 2006
DNA組換え修復酵素Rad52のSUMO修飾による制御機構の解析

第3回東北大学バイオサイエンスシンポジウム仙台国際センター（仙台市）, 2006
BLMのDNA二重鎖切断部位への迅速な集積

第3回東北大学バイオサイエンスシンポジウム仙台国際センター（仙台市）, 2006
The INO80 and SWR1 chromatin remodeling complexes are required for the regulation of homologous recombination in Saccharomyces cerevisiae.

20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB congress. Kyoto, Japan, 2006
Possible functions of yeast Saccharomyces cerevisiae Rmi1/Nce4 in DNA repair.

20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB congress., 2006
Most of defective mutants of pol31, S. cerevisiae Pold second subunit, require Mgs1 and Rad18/ Rad5/ Mms2 for their efficient cell growth.

20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB congress. Kyoto, Japan, 2006
Function of Cdt1 in Preventing Rereplication of DNA in Xenopus Egg Extracts.

20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB congress. Kyoto, Japan, 2006
Elg1, suppressor of genome instability, is involved in DSB repair by homologous recombination repair.

20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB congress. Kyoto, Japan, 2006
BLM functions together with XRCC3 for resumption of stalled replication forks.

20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB congress. Kyoto, Japan, 2006
Analysis of biological meaning of sumoylated Rad52 in homologous recombination.

20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB congress. Kyoto, Japan, 2006
過度のDNA複製ライセンス化活性に起因する過剰なDNA複製

第65回日本癌学会学術総会パシフィコ横浜, 2006
ヒストンH3点突然変異体の機能の解析

第45回日本薬学会東北支部大会山形大学, 2006
RecQL1 siRNAの処理によるがん細胞死

第45回日本薬学会東北支部大会山形大学, 2006
DNA二本鎖切断修復におけるRecQL4の機能の解析

第45回日本薬学会東北支部大会山形大学, 2006
Cdc6過剰添加によるDNA複製開始の抑制

DNA複製・分配ワークショップ静岡県熱海市・KKRホテル熱海, 2006
Rad52のSUMO修飾による制御

組換え、染色体再編ワークショップ兵庫県淡路島夢舞台国際会議場, 2006
The importance of Mgs1 and Rad18 for the survival of pol31 defective mutants revealed through systematic domain analyses of Pol31, the second subunit S. cerevisiae Pold.

2006
Rmi1/Nce4, a subunit of the Sgs1-Top3 complex, of Saccharomyces cerevisiae is involved in homologous recombination and establishment of sister chromatid cohesion.

2006
Systematic genetical analyses for one of the essential subunits of DNA polymerase delta (Pold) in Saccharomyces cerevisiae.

2006
Sgs1-Top3 complex, contributes to sister chromatid cohesion in yeast Saccharomyces cerevisiae.

2006
The INO80 and SWR1 chromatin remodeling complexes are required for the regulation of homologous recombination in Saccharomyces cerevisiae.

20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB congress. Kyoto, Japan, 2006
Most of defective mutants of pol31, S. cerevisiae Pold second subunit, require Mgs1 and Rad18/ Rad5/ Mms2 for their efficient cell growth.

20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB congress. Kyoto, Japan, 2006
Function of Cdt1 in Preventing Rereplication of DNA in Xenopus Egg Extracts.

20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB congress. Kyoto, Japan, 2006
Elg1, suppressor of genome instability, is involved in DSB repair by homologous recombination repair.

20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB congress. Kyoto, Japan, 2006
BLM functions together with XRCC3 for resumption of stalled replication forks.

20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB congress. Kyoto, Japan, 2006
Analysis of biological meaning of sumoylated Rad52 in homologous recombination.

20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB congress. Kyoto, Japan, 2006
出芽酵母におけるアクチン関連タンパク質Arp4の機能の解析

第２２回染色体ワークショップ仙台, 2005
真核細胞SMC5/6複合体の機能の解析

日本薬学会第125年会東京, 2005
クロマチン構造変換複合体のDNA修復機構の解析

日本薬学会第125年会東京, 2005
Tap54α の DNA 複製への寄与の解析

日本薬学会第125年会東京, 2005
出芽酵母Dpb11のDNA傷害時における機能の解析

第2回東北大学バイオサイエンスシンポジウム仙台国際センター（仙台市）, 2005
ブルーム症候群原因遺伝子産物の相同組換え修復における機能

第2回東北大学バイオサイエンスシンポジウム仙台国際センター（仙台市）, 2005
DNA複製開始制御機構におけるCdt1とgemininの構造と機能の関係

第2回東北大学バイオサイエンスシンポジウム仙台国際センター（仙台市）, 2005
The UBC9/SUMO modification pathway prevents genomic instability by promoting recovery from intra-S DNA damage (poster).

FASEB meeting on DNA recombination Colorado, USA, 2005
DNA複製開始制御とゲノム倍数性の維持-DNA複製ライセンス化因子Cdt1を中心として-

第7 回日本進化学会東北大学川内キャンパス（仙台市）, 2005
ブルーム症候群原因遺伝子産物の機能の解析

第64回日本癌学会学術総会ロイトン札幌ほか（札幌市）, 2005
複製フォークと SUMO 化修飾

国立遺伝学研究所研究集会国立遺伝学研究所（静岡県三島市）, 2005
BLM acts together with XRCC3 upon damage inductio.

2005
Analysis for suppression of DNA replication caused by an excess Cdt1.

2005
ゲノム安定性維持機構におけるSUMO化修飾の生物学的意義の解析

第44回日本薬学会東北支部大会東北薬科大学（仙台）, 2005
DNA複製開始制御機構におけるCdt1とgemininの構造と機能の関係

第44回日本薬学会東北支部大会東北薬科大学（仙台）, 2005
DNA複製チェックポイント因子RAD17とBLMの解析

第44回日本薬学会東北支部大会東北薬科大学（仙台）, 2005
Systematic analyses of functional domains of the second subunit of S. cerevisiae DNA Polymerase d, Pol31.

The 5th 3R symposium Awaji Yumebutai International conference center, Hyogo, Japan, 2005
Dpb11, the budding yeast homologue of TopBP1, functions with the checkpoint clamp in recombination repair.

The 5th 3R symposium Yumebutai International conference center, Hyogo, Japan, 2005
BLM is an early responder to DNA double strand breaks.

The 5th 3R symposium Awaji Yumebutai International conference center, Hyogo, Japan, 2005
BLM functions in the damage tolerance pathway involving XRCC3.

The 5th 3R symposium Awaji Yumebutai International conference center, Hyogo, Japan, 2005

Professional Memberships

Works

Research Projects

新たなDNA修復、組み換え機構及びその発生学的役割

1995 - 1996
Novel mechanism and developmental roles of repair recombination

1995 - 1996

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