研究者業績

宮村 浩徳

miyamura hironori

基本情報

所属
藤田医科大学 医学部 医学科 産婦人科学 講師
学位
博士(医学)(2013年3月)

J-GLOBAL ID
201501004478802341
researchmap会員ID
7000012956

日本産科婦人科学会・専門医・指導医

日本周産期新生児医学会・周産期(母体・胎児)専門医・指導医

日本人類遺伝学会・臨床遺伝専門医

日本生殖医学会・生殖医療専門医・指導医

日本がん治療認定医機構がん治療認定医

日本産科婦人科内視鏡学会・技術認定医

日本内視鏡外科学会・技術認定医

母体保護法指定医

日本医師会認定産業医


論文

 56
  • Eiji Nishio, Shota Oikawa, Eriko Sakakibara, Miho Ishikawa, Kiriko Kotani, Hikari Yoshizawa, Hironori Miyamura, Takanori Hayashi, Haruki Nishizawa
    Cureus 17(3) e81185 2025年3月  
    BACKGROUND: When using assisted reproductive technology, there are cases where, despite the transfer of a good embryo, sometimes pregnancy may not be the case. Thus, during hormone replacement cycle implantation, it is important to synchronize the number of days of progesterone administration with the degree of embryo maturity. This study aimed to compare the outcomes of the administration of oral dydrogesterone for the duration of progestin use during the hormone replacement cycle for frozen-thawed blastocyst transfer. MATERIAL AND METHODS: The primary outcome of this study was the clinical pregnancy rate. We performed a retrospective cohort study of patients who underwent frozen-thawed blastocyst transfers between January 2017 and December 2024. According to our standard protocol, a vitrified-warmed blastocyst transfer was performed using dydrogesterone, which was administered orally at our center. A total of 554 cases were included in the study. Using the Gardner classification to evaluate the quality of blastocysts, grade AA was classified as the best quality, the AB/BA group as good quality, and the BB group as fair quality. We classified the 554 cases into 317 AA, 163 AB/BA, and 74 BB cases using the Gardner classification. Based on the duration of progestin administration, patients were divided into four groups: 120 hours (120 h), 132 hours (132 h), 144 hours (144 h), and 156 hours (156 h). We used the Shapiro-Wilk method and the Steel-Dwass test to determine whether there were differences in patients' background age and BMI among the four groups (120 h, 132 h, 144 h, and 156 h). We used Fisher's exact test and the Bonferroni method to determine whether there were differences in the final outcome of pregnancy rate between the four groups of 120 h, 132 h, 144 h, and 156 h. RESULTS: In the analysis of all embryos, the pregnancy rate at each timepoint of the primary evaluation was significantly higher in the 144-h group than in the 132-h group. Next, on analyzing the results by embryo grade, there was no difference in the pregnancy rate at each timepoint in the AA group. In the AB/BA group, the pregnancy rate was higher in the 144-h group than in the 132-h group. In the BB group, the pregnancy rate was higher in the 144-h group than in the 132-h group. CONCLUSION: This study clarified two aspects. First, the pregnancy rate in the 144-h group was significantly higher than that in the 132-h group in the analysis of all embryos. Second, the window of implantation may be more important for poor-quality embryos. This study showed that the oral administration of dydrogesterone requires a window of implantation of at least 144 hours.
  • Hironori Miyamura, Kyohei Takada, Akiko Ohwaki, Arata Kobayashi, Mayuko Ito, Hiroyuki Nomura, Eiji Nishio, Haruki Nishizawa
    Asian journal of endoscopic surgery 17(2) e13298 2024年4月  
    INTRODUCTION: The da Vinci SP surgical system is a surgical platform capable of implementing robotic-assisted surgery through a single port and was first introduced in Japan at our hospital. In this paper, we describe our experience of the initial introduction of the da Vinci SP surgical system and its surgical outcomes. This is the first report on the surgical outcomes of using da Vinci SP, and its comparison with the conventional system in Japan. METHODS: After developing an application for a highly difficult new medical technology in-house, we compared the surgical outcomes (median values) of 15 patients who had undergone total hysterectomy at our hospital using the da Vinci SP (1-port) system (SP group) for uterine myoma after March 2023 and of 154 patients who underwent total hysterectomy using the conventional da Vinci Xi (four ports) system (Xi group) for uteri weighing <500 g. RESULTS: The results of the comparison of the characteristics between 15 patients in the SP group and 154 patients in the Xi group were as follows: uterus weight (g): 230 (90-500) versus 222 (55-496) (p = .35); surgical time (minutes): 199 (171-251) versus 198 (88-387) (p = .63); intraoperative blood loss (mL): 13 (5-82) versus 20 (2-384) (p = .17); and rate of surgical complication (%): 0.0 versus 1.3 (p = .66). The data indicated a comparable weight of the resected uterus, surgical time, intraoperative blood loss, and rate of surgical complications between the two groups. CONCLUSION: Robotic-assisted total hysterectomy using the da Vinci SP surgical system allowed clinicians to safely perform surgeries according to the conventional systems.
  • Seira Nishibe-Toyosato, Yosuke Ando, Yutaka Torii, Ryoko Ichikawa, Akiko Owaki, Hironori Miyamura, Eiji Nishio, Hidezo Matsuda, Naho Tsujii-Fujii, Akane Shimato-Isobe, Kotone Mukaiji, Kaori Ito, Takahiro Hayashi, Takuma Fujii, Shigeki Yamada
    In vivo (Athens, Greece) 38(5) 2374-2382 2024年  
    BACKGROUND/AIM: The frequency rate of injection site reactions (ISR) due to fosaprepitant meglumine (Fos APR) has been shown to vary depending on the types of combined anticancer drug. This study aimed to elucidate the impact of Fos APR on ISR in patients receiving paclitaxel and carboplatin, with and without bevacizumab therapy (TC±Bev). PATIENTS AND METHODS: This study focused on patients with gynecologic cancer (n=93) who received TC±Bev administration at Fujita Health University Hospital from March 2016 to February 2020, and monitored up to six cycles. The patients were randomly assigned to the Fos APR group (n=47) and the Aprepitant (APR) group (n=46). Using Visual Infusion Phlebitis (VIP) scores, ISR was evaluated by comparing the VIP scores of all cycles using a linear mixed model. The risk factors that contribute to the occurrence of vascular pain throughout all cycles were also examined. RESULTS: The VIP scores of all cycles showed a near significant intergroup difference (p=0.071). Factors that affected the development of vascular pain included Fos APR and age (p=0.027 and 0.049, respectively). Regarding age, patients aged <65 years had a higher risk. Four patients underwent a switch from the originally assigned neurokinin-1 receptor antagonist; in all of these cases, Fos APR was changed to APR for vascular pain. CONCLUSION: Fos APR may increase the risk for ISR associated with TC±Bev therapy for gynecological cancer.
  • 水野 雄介, 宮村 浩徳, 小谷 燦璃古, 高橋 龍之介, 會田 訓子, 坂部 慶子, 森山 佳則, 西澤 春紀, 関谷 隆夫, 藤井 多久磨
    東海産科婦人科学会雑誌 59 426-426 2023年3月  
  • 森山 佳則, 等々力 彩, 大脇 晶子, 坂部 慶子, 野田 佳照, 宮村 浩徳, 関谷 隆夫, 西澤 春紀
    日本産科婦人科学会雑誌 75(臨増) S-552 2023年2月  

MISC

 27

書籍等出版物

 4

講演・口頭発表等

 198